Tissue expression
Cell line expression
Protein structure
LRRK2
Leucine rich repeat kinase 2DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals | 38 references | Polyclonal |
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| GeneTex | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Enzo Life Sciences | 1 references | Polyclonal |
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