Tissue expression
Cell line expression
Protein structure
OCLN
OccludinPPP1R115
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Top validated antibodies |
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Invitrogen Antibodies | 71-1500 | 457 references | Polyclonal |
WB
EL
ICC
IP
IHC
OA |
|
antibodies-online | ABIN395206 | 5 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
|
Boster Biological Technology | A01246-2 | 5 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
|
Novus Biologicals | H00004950-M01 | 2 references | Monoclonal |
WB
EL
ICC
IP |
|
GeneTex | GTX85016 | 1 references | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider