Tissue expression
Cell line expression
Protein structure
ORAI1
ORAI calcium release-activated calcium modulator 1CRACM1, FLJ14466, TMEM142A
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
Top validated antibodies |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Novus Biologicals | 3 references | Monoclonal |
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| GeneTex | 3 references | Polyclonal |
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| LSBio | Polyclonal |
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| Proteintech Group | 43 references | Polyclonal |
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