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Protein structure
ACACA
Acetyl-CoA carboxylase alphaACAC, ACC, ACC1
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  21923-1-AP |
129 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 21923-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| GeneTex | GTX132081 |
2 references | Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C198585 |
Polyclonal |
WB
EL
IHC
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| NovoPro Bioscience Inc. | 107732 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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