HSPE1

This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3. [provided by RefSeq, Feb 2011]

Description

heat shock 10kDa protein 1 (chaperonin 10)

Protein family

-

Chromosome

2:q33.1 (198364718 - 198368181)

Ensembl ID

ENSG00000115541  (ver. 69.37)

Orthologs

Mouse Hspe1: ENSMUSG00000073676

Human splice variants
Mouse splice variants