CCL19

This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]

Description

C-C motif chemokine ligand 19

Tissue specificity

Tissue enriched (lymphoid tissue)

Predicted location

Secreted to blood

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

9 (34689570 - 34691276)

Ensembl ID

ENSG00000172724  (ver. 103.38)

Orthologs

Mouse Ccl19: ENSMUSG00000071005

UniProt

Q99731

neXtProt

NX_Q99731

Human splice variants
Mouse splice variants

Protein structure