PDGFB

gene product
SIS, SSV
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
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190 antibodies from 22 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
6 antibodies
Atlas Antibodies
1 antibody
Santa Cruz Biotechnology
1 antibody
antibodies-online
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Novus Biologicals
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LifeSpan BioSciences, Inc.
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Acris Antibodies GmbH
16 antibodies
Aviva Systems Biology
6 antibodies
Thermo Fisher Scientific Pierce
6 antibodies
GeneTex
5 antibodies
Abbiotec
2 antibodies
Biorbyt
5 antibodies
Abnova Corporation
7 antibodies
Creative Biomart
21 antibodies
GenWay
6 antibodies
EMD Millipore
3 antibodies
Abiocode, Inc.
1 antibody
Bioworld Technology, Inc
1 antibody
Signalway Antibody LLC
1 antibody
Sigma-Aldrich
3 antibodies
United States Biological
3 antibodies
RayBiotech, Inc.
2 antibodies