Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
ITGA2B
Integrin subunit alpha 2bCD41, CD41B, GP2B, PPP1R93
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Top validated antibodies |
|||||
| Proteintech Group |  24552-1-AP |
33 references | Polyclonal |
WB
EL
IP
IHC
|
|
| LSBio | LS-C191835 |
Monoclonal |
WB
EL
IHC
|
||
| antibodies-online | ABIN1724822 |
2 references | Monoclonal |
WB
EL
IHC
FC
|
|
| NSJ Bioreagents | RQ4069 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
||
| GeneTex | GTX76011 |
14 references | Monoclonal |
IP
IHC
FC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider