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ITGA2B
Integrin subunit alpha 2bCD41, CD41B, GP2B, PPP1R93
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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| Proteintech Group |  24552-1-AP |
15 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN1724822 |
2 references | Monoclonal |
WB
EL
IHC
FC
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| GeneTex | GTX76011 |
14 references | Monoclonal |
IP
IHC
FC
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| Biorbyt | orb153450 |
Monoclonal |
WB
EL
ICC
IHC
FC
|
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| Invitrogen Antibodies | PA5-79527 |
2 references | Polyclonal |
WB
IHC
OA
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