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Protein structure
DNM1
Dynamin 1DNM
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA1-660 |
22 references | Polyclonal |
WB
ICC
FC
OA
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| Proteintech Group | 18205-1-AP |
6 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| LSBio | LS-C198893 |
Polyclonal |
WB
EL
IHC
|
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| Boster Biological Technology | A02536-2 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
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| Novus Biologicals | NB110-60491 |
Monoclonal |
WB
EL
IHC
FC
|
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