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Protein structure
BMP4
Bone morphogenetic protein 4BMP2B
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| Novus Biologicals |  NBP2-52424 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Invitrogen Antibodies | PA5-27288 |
2 references | Polyclonal |
WB
ICC
IHC
OA
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| OriGene | UM500038 |
1 references | Monoclonal |
WB
ICC
IHC
OA
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| Proteintech Group | 12492-1-AP |
13 references | Polyclonal |
WB
EL
IHC
|
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| antibodies-online | ABIN4284902 |
Monoclonal |
WB
EL
ICC
IHC
FC
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