Tissue expression
Cell line expression
Protein structure
CCR1
C-C motif chemokine receptor 1CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA1-41062 | 4 references | Polyclonal |
WB
IHC
FC
OA |
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Novus Biologicals | NB100-56334 | 6 references | Polyclonal |
WB
ICC
IHC
FC |
|
Abnova Corporation | PAB0176 | 2 references | Polyclonal |
WB
IHC
FC
|
|
antibodies-online | ABIN2657065 | Monoclonal |
WB
EL
IHC
FC |
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OriGene | AP31997PU-N | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider