Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10403-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10403-1-AP, RRID:AB_2122853
- Product name
- ICT1 antibody
- Antibody type
- Polyclonal
- Description
- ICT1 antibody (Cat. #10403-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome.
The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly.
MPV17L2 is required for ribosome assembly in mitochondria.
Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria.
Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency.
Reyes A, Favia P, Vidoni S, Petruzzella V, Zeviani M
PLoS genetics 2020 Jul;16(7):e1008923
PLoS genetics 2020 Jul;16(7):e1008923
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
Lavdovskaia E, Kolander E, Steube E, Mai MM, Urlaub H, Richter-Dennerlein R
Nucleic acids research 2018 Sep 19;46(16):8471-8482
Nucleic acids research 2018 Sep 19;46(16):8471-8482
The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome.
Rozanska A, Richter-Dennerlein R, Rorbach J, Gao F, Lewis RJ, Chrzanowska-Lightowlers ZM, Lightowlers RN
The Biochemical journal 2017 Jun 13;474(13):2145-2158
The Biochemical journal 2017 Jun 13;474(13):2145-2158
The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly.
Tu YT, Barrientos A
Cell reports 2015 Feb 17;10(6):854-864
Cell reports 2015 Feb 17;10(6):854-864
MPV17L2 is required for ribosome assembly in mitochondria.
Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A
Nucleic acids research 2014 Jul;42(13):8500-15
Nucleic acids research 2014 Jul;42(13):8500-15
Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria.
Dujeancourt L, Richter R, Chrzanowska-Lightowlers ZM, Bonnefoy N, Herbert CJ
Mitochondrion 2013 Nov;13(6):871-80
Mitochondrion 2013 Nov;13(6):871-80
Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency.
Serre V, Rozanska A, Beinat M, Chretien D, Boddaert N, Munnich A, Rötig A, Chrzanowska-Lightowlers ZM
Biochimica et biophysica acta 2013 Aug;1832(8):1304-12
Biochimica et biophysica acta 2013 Aug;1832(8):1304-12
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The ICT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ICT1. This antibody recognizes human, mouse, rat antigen. The ICT1 antibody has been validated for the following applications: ELISA, WB analysis.