MA1-35368

antibody from Invitrogen Antibodies
Targeting: KRT76 HUMCYT2A, KRT2B, KRT2P
Provider product page for MA1-35368
Western blot
Immunohistochemistry

Antibody data

Product number
MA1-35368 - Provider product page
Provider
Invitrogen Antibodies
Product name
Cytokeratin Pan Type II Monoclonal Antibody (AE3)
Antibody type
Monoclonal
Antigen
Other
Description
Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Reactivity
Human, Mouse, Rat, Bovine, Chicken/Avian, Rabbit
Host
Mouse
Isotype
IgG
Antibody clone number
AE3
Vial size
250 µg
Concentration
1 mg/mL
Storage
4° C
KRT76 protein structure - MA1-35368 shown in red.