13-0519-80

antibody from Invitrogen Antibodies
Targeting: ITGB3 CD61, GP3A, GPIIIa
Provider product page for 13-0519-80

Antibody data

Product number
13-0519-80 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), Biotin, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ~120 kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin. Applications Reported: This 23C6 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 23C6 antibody has been tested by flow cytometric analysis of peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Biotin
Isotype
IgG
Antibody clone number
23C6
Vial size
25 µg
Concentration
0.5 mg/mL
Storage
4° C, store in dark, DO NOT FREEZE!
ITGB3 protein structure - 13-0519-80 shown in red.