Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358745 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Middle Region
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma.
Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation.
Regulation of the Wnt signaling pathway by disabled-2 (Dab2).
WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.
Tanaka S, Sugimachi K, Kameyama T, Maehara S, Shirabe K, Shimada M, Wands JR, Maehara Y
Hepatology (Baltimore, Md.) 2003 May;37(5):1122-9
Hepatology (Baltimore, Md.) 2003 May;37(5):1122-9
Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation.
Soon LL, Yie TA, Shvarts A, Levine AJ, Su F, Tchou-Wong KM
The Journal of biological chemistry 2003 Mar 28;278(13):11465-70
The Journal of biological chemistry 2003 Mar 28;278(13):11465-70
Regulation of the Wnt signaling pathway by disabled-2 (Dab2).
Hocevar BA, Mou F, Rennolds JL, Morris SM, Cooper JA, Howe PH
The EMBO journal 2003 Jun 16;22(12):3084-94
The EMBO journal 2003 Jun 16;22(12):3084-94
WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Su F, Overholtzer M, Besser D, Levine AJ
Genes & development 2002 Jan 1;16(1):46-57
Genes & development 2002 Jan 1;16(1):46-57
Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.
Xie D, Nakachi K, Wang H, Elashoff R, Koeffler HP
Cancer research 2001 Dec 15;61(24):8917-23
Cancer research 2001 Dec 15;61(24):8917-23
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