BS8537

antibody from Bioworld Technology, Inc

Targeting: RIOX2 FLJ14393, JMJD10, mdig, MINA, MINA53, NO52

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8537

Provider

Bioworld Technology, Inc

Product name

MINA polyclonal antibody

Antibody type

Polyclonal

Antigen

Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; 60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX; MINA; MDIG; MINA53; NO52

Description

Mina53, also known as MINA (MYC induced nuclear antigen), MDIG or NO52, is a 465 amino acid protein that contains one JmjC domain and localizes to the nucleus. Expressed in placenta, liver, heart, pancreas and skeletal muscle, Mina53 is thought to be involved in ribosome biogenesis, specifically in the assembly of pre-ribosomal particles. Via its involvement in ribosome biogenesis, Mina53 may play an important role in cell growth and survival, as well as overall cellular proliferation events. Mina53 expression is upregulated in esophageal squamous cell carcinoma (ESCC), colon cancer and lung cancer tissues, suggesting that Mina53 may be involved in tumorigenesis. Multiple isoforms of Mina53 exist due to alternative splicing events.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.