17-0668-42

antibody from Invitrogen Antibodies
Targeting: CEACAM1 BGP, BGP1, CD66a
Provider product page for 17-0668-42

Antibody data

Product number
17-0668-42 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD66 Monoclonal Antibody (CD66a-B1.1), APC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically. Applications Reported: This CD66a-B1.1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This CD66a-B1.1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.06 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
CD66a-B1.1
Vial size
100 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
CEACAM1 protein structure - 17-0668-42 shown in red.