17-0668-42

antibody from Invitrogen Antibodies
Targeting: CEACAM1 BGP, BGP1, CD66a
Provider product page for 17-0668-42

Antibody data

Product number
17-0668-42 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD66 Monoclonal Antibody (CD66a-B1.1), APC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.
Antibody clone number
CD66a-B1.1
Concentration
5 µL/Test
CEACAM1 protein structure - 17-0668-42 shown in red.