C8orf4

gene product
hTC-1, TC-1
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
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64 antibodies from 18 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Novus Biologicals
1 antibody
Invitrogen Antibodies
3 antibodies
antibodies-online
20 antibodies
St John's Laboratory
1 antibody
LifeSpan BioSciences, Inc.
7 antibodies
Biorbyt
7 antibodies
Abnova Corporation
1 antibody
Aviva Systems Biology
1 antibody
OriGene
1 antibody
GeneTex
2 antibodies
Boster Biological Technology
1 antibody
Proteintech Group
1 antibody
United States Biological
12 antibodies
MyBioSource
1 antibody
Sigma-Aldrich
1 antibody
Creative Diagnostics
2 antibodies
Creative Biolabs
1 antibody