Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB3869G - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal Nectin-2/CD112 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse Nectin-2/CD112 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Nectin-2/CD112 or recombinant mouse CD155/PVR is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1.
Du X, de Almeida P, Manieri N, de Almeida Nagata D, Wu TD, Harden Bowles K, Arumugam V, Schartner J, Cubas R, Mittman S, Javinal V, Anderson KR, Warming S, Grogan JL, Chiang EY
Proceedings of the National Academy of Sciences of the United States of America 2018 Dec 11;115(50):E11731-E11740
Proceedings of the National Academy of Sciences of the United States of America 2018 Dec 11;115(50):E11731-E11740
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Detection of Nectin-2/CD112 in C2C12 Mouse Cell Line by Flow Cytometry. C2C12 mouse myoblast cell line was stained with Rat Anti-Mouse Nectin-2/CD112 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB3869G, filled histogram) or isotype control antibody (Catalog # IC006G, open histogram). View our protocol for Staining Membrane-associated Proteins.