Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 337410 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#337410, RRID:AB_2269088
- Product name
- PE anti-human CD112 (Nectin-2)
- Antibody type
- Monoclonal
- Antigen
- CD112 (Nectin-2)
- Description
- CD112, known as poliovirus receptor related 2 protein (PRR2), Nectin-2, or Hve B, is a type I transmembrane glycoprotein, a member of the Ig gene superfamily. It is primarily found on myelomonocytic cells, megakaryocytes, dendritic cells, mast cells, CD34-positive stem cells, endothelial cells, epithelial cells, and neuronal cells. CD112 functions as a receptor for α-herpes viruses HSV-1 and pseudorabies virus (PRV). CD112 is an adhesion molecule involved in the formation of cell junction and regulation of NK- and T-cells mediated cytotoxicity through interaction with CD226 (DNAM-1) and other nectin family molecules.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- KG1a (human myeloid leukemia cell line) stained with TX31 PE
- Conjugate
- Yellow dye