Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB2659P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Nectin-4/PVRL4 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Nectin-4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, does not cross-react with recombinant human Nectin-1, -2, -3, or recombinant mouse Nectin-4.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells.
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins.
Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis.
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Hiramoto T, Tahara M, Liao J, Soda Y, Miura Y, Kurita R, Hamana H, Inoue K, Kohara H, Miyamoto S, Hijikata Y, Okano S, Yamaguchi Y, Oda Y, Ichiyanagi K, Toh H, Sasaki H, Kishi H, Ryo A, Muraguchi A, Takeda M, Tani K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jan 8;28(1):129-141
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jan 8;28(1):129-141
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins.
Muñoz-Alía MA, Russell SJ
Viruses 2019 Jul 27;11(8)
Viruses 2019 Jul 27;11(8)
Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis.
Gourru-Lesimple G, Mathieu C, Thevenet T, Guillaume-Vasselin V, Jégou JF, Boer CG, Tomczak K, Bloyet LM, Giraud C, Grande S, Goujon C, Cornu C, Horvat B
Journal of dermatological science 2017 May;86(2):97-105
Journal of dermatological science 2017 May;86(2):97-105
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Noyce RS, Bondre DG, Ha MN, Lin LT, Sisson G, Tsao MS, Richardson CD
PLoS pathogens 2011 Aug;7(8):e1002240
PLoS pathogens 2011 Aug;7(8):e1002240
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Nectin-4 in MCF-7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human Nectin-4 PE-conjugated Monoclonal Antibody (Catalog # FAB2659P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.