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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB2659P - Provider product page
- Provider
- R&D Systems
- Product name
- Human Nectin-4 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Nectin-4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, does not cross-react with recombinant human Nectin-1, -2, -3, or recombinant mouse Nectin-4.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q96NY8- Isotype
- IgG
- Antibody clone number
- 337516
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis.
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Gourru-Lesimple G, Mathieu C, Thevenet T, Guillaume-Vasselin V, Jégou JF, Boer CG, Tomczak K, Bloyet LM, Giraud C, Grande S, Goujon C, Cornu C, Horvat B
Journal of dermatological science 2017 May;86(2):97-105
Journal of dermatological science 2017 May;86(2):97-105
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Noyce RS, Bondre DG, Ha MN, Lin LT, Sisson G, Tsao MS, Richardson CD
PLoS pathogens 2011 Aug;7(8):e1002240
PLoS pathogens 2011 Aug;7(8):e1002240
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of Nectin-4 in MCF-7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human Nectin-4 PE-conjugated Monoclonal Antibody (Catalog # FAB2659P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.
