BS7548

antibody from Bioworld Technology, Inc
Targeting: HJV haemojuvelin, hemojuvelin, HFE2, HFE2A, JH, RGMC
Provider product page for BS7548
Western blot
Immunohistochemistry

Antibody data

Product number
BS7548 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HFE2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HFE2.
Description
The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HJV protein structure - BS7548 shown in red.