DPABH-21476

antibody from Creative Diagnostics
Targeting: MARCHF1 FLJ20668, MARCH-I, MARCH1, RNF171
Provider product page for DPABH-21476
No application information provided.

Antibody data

Product number
DPABH-21476 - Provider product page
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPABH-21476, RRID:AB_2504610
Product name
Rabbit Anti-Human MARCH1 Polyclonal Antibody
Antibody type
Polyclonal
Description
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]
MARCHF1 protein structure - DPABH-21476 shown in red.