Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 657404 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#657404, RRID:AB_2562670
- Product name
- Alexa Fluor® 488 anti-Tubulin Beta 3 (TUBB3)
- Antibody type
- Monoclonal
- Antigen
- Fusion protein
- Description
- Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Green dye
- Antibody clone number
- AA10
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human lung adenocarcinoma cell line A549 was treated with BioLegendâs Fixation Buffer (Cat. No. 420801) and Permeabilization Wash Buffer (Cat. No. 421002), and then stained with TUBB3 (clone AA10) Alexa Fluor® 488 (filled hisotogram) or mouse IgG2a, κ Alexa Fluor® 488 isotype control (open histogram).
- Conjugate
- Green dye