WISP3

gene product
CCN6
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
170 antibodies from 22 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
66 antibodies
Abnova Corporation
3 antibodies
Biorbyt
14 antibodies
LifeSpan BioSciences, Inc.
20 antibodies
Acris Antibodies GmbH
7 antibodies
OriGene
4 antibodies
Aviva Systems Biology
1 antibody
Novus Biologicals
4 antibodies
Invitrogen Antibodies
4 antibodies
GeneTex
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
St John's Laboratory
2 antibodies
Atlas Antibodies
3 antibodies
ProSci
2 antibodies
MyBioSource
1 antibody
United States Biological
13 antibodies
Creative Diagnostics
3 antibodies
Creative Biolabs
2 antibodies
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
1 antibody
Abbexa
3 antibodies