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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- NBP2-34758-0.1 mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal MUC5AC Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
- Reactivity
- Human, Mouse, Rat, Bovine, Chicken/Avian, Feline, Porcine, Rabbit, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MUC5AC Antibody (SPM297) - Azide and BSA Free [NBP2-34758] - Paraffin-embedded human Gastric Carcinoma.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: MUC5AC Antibody (SPM297) - Azide and BSA Free [NBP2-34758] - Intracellular flow cytometry of fixed (70% ethanol or 80% methanol) and permeabilized A549 cells using MUC5AC MAb (SPM297) (red) and isotype control (green).
