Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 14-9001-82 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Cytokeratin Pan Type I Monoclonal Antibody (AE1), eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The monoclonal antibody AE1 recognizes many members of the acidic (Type I) family of cytokeratins. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an alpha-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these cytokeratins, and their expression can help identify the origin of a neoplasm.
- Antibody clone number
- AE1
- Concentration
- 0.5 mg/mL
Submitted references Comparison of Multiplexed Immunofluorescence Imaging to Chromogenic Immunohistochemistry of Skin Biomarkers in Response to Monkeypox Virus Infection.
Analysis of cellular autofluorescence in touch samples by flow cytometry: implications for front end separation of trace mixture evidence.
Flow cytometry dataset for cells collected from touched surfaces.
Sood A, Sui Y, McDonough E, Santamaría-Pang A, Al-Kofahi Y, Pang Z, Jahrling PB, Kuhn JH, Ginty F
Viruses 2020 Jul 23;12(8)
Viruses 2020 Jul 23;12(8)
Analysis of cellular autofluorescence in touch samples by flow cytometry: implications for front end separation of trace mixture evidence.
Katherine Philpott M, Stanciu CE, Kwon YJ, Bustamante EE, Greenspoon SA, Ehrhardt CJ
Analytical and bioanalytical chemistry 2017 Jul;409(17):4167-4179
Analytical and bioanalytical chemistry 2017 Jul;409(17):4167-4179
Flow cytometry dataset for cells collected from touched surfaces.
Kwon YJ, Stanciu CE, Philpott MK, Ehrhardt CJ
F1000Research 2016;5:390
F1000Research 2016;5:390
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- MCF7 cell lysates prepared under reducing conditions were resolved by SDS-PAGE then immunoblotted with 2 µg/mL of Anti-Acidic Cytokeratin Purified.Bands were visualized using Anti-Mouse IgG HRP.
