sc-14939

Nima Aden, Anna Nuttall, Xu Shiwen, Patricia de Winter, Andrew Leask, Carol M Black, Christopher P Denton, David J Abraham, Richard J Stratton
Journal of Investigative Dermatology 2010 May;130(9):2191-2200

Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor.

Masuko K, Murata M, Yudoh K, Shimizu H, Beppu M, Nakamura H, Kato T
BMC research notes 2010 Jan 15;3:5

FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells.

Samarin J, Wessel J, Cicha I, Kroening S, Warnecke C, Goppelt-Struebe M
The Journal of biological chemistry 2010 Feb 12;285(7):4328-36

Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein.

Bohr W, Kupper M, Hoffmann K, Weiskirchen R
PloS one 2010 Dec 30;5(12):e16000

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1.

Kang Q, Chen A
Laboratory investigation; a journal of technical methods and pathology 2009 Nov;89(11):1275-90

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF.

Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Picard D
The EMBO journal 2009 Mar 4;28(5):523-32

Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling.

Tang Y, Zheng S, Chen A
Endocrinology 2009 Jul;150(7):3011-20

The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth.

Bennewith KL, Huang X, Ham CM, Graves EE, Erler JT, Kambham N, Feazell J, Yang GP, Koong A, Giaccia AJ
Cancer research 2009 Feb 1;69(3):775-84

Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress.

Lin J, Zheng S, Chen A
Laboratory investigation; a journal of technical methods and pathology 2009 Dec;89(12):1397-409

Curcumin suppresses expression of low-density lipoprotein (LDL) receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells.

Kang Q, Chen A
British journal of pharmacology 2009 Aug;157(8):1354-67

Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2.

Li MH, Sanchez T, Pappalardo A, Lynch KR, Hla T, Ferrer F
Molecular cancer research : MCR 2008 Oct;6(10):1649-56

Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression.

Bourgier C, Haydont V, Milliat F, François A, Holler V, Lasser P, Bourhis J, Mathé D, Vozenin-Brotons MC
Gut 2005 Mar;54(3):336-43

No comments: Submit comment

Supportive validation

Submitted by: per
Main image
Experimental details: Western blot analysis of antibody specificity using a routine panel composed of IgG/HSA-depleted human plasma and protein lysates from selected human tissues and cell lines.
Validation comment: Band of predicted size in kDa (+/-20%) with additional bands present.
Primary Ab dilution: 1:500
Secondary Ab dilution: 1:2000
Lane 1: Marker [kDa]: 230, 110, 82, 49.3, 32.2, 25.5, 17.6
Lane 2: RT-4
Lane 3: U-251MG sp
Lane 4: Human Plasma
Lane 5: Liver
Lane 6: Tonsil
Theoretical target weight: [kDa] 38

Supportive validation

Submitted by: per
Main image
Experimental details: Immunohistochemical staining of human smooth muscle shows cytoplasmic and nuclear positivity in smooth muscle cells.
Validation comment: Staining pattern partly consistent with experimental and/or bioinformatic data.