Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PB9541 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-CTGF Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for CCN2/CTGF detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CCN2/CTGF information: Molecular Weight: 38091 MW; Subcellular Localization: Secreted, extracellular space, extracellular matrix . Secreted ; Tissue Specificity: Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Inhibition of the histone methyltransferase EZH2 induces vascular stiffness.
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Cathepsin B/NLRP3/GSDMD axis-mediated macrophage pyroptosis induces inflammation and fibrosis in systemic sclerosis.
TH5487, a small molecule inhibitor of OGG1, attenuates pulmonary fibrosis by NEDD4L-mediated OGG1 degradation.
Ubiquitin-specific protease 2 regulates Ang Ⅱ-induced cardiac fibroblasts activation by up-regulating cyclin D1 and stabilizing β-catenin in vitro.
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.
Arl4c promotes the growth and drug resistance of pancreatic cancer by regulating tumor-stromal interactions.
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway.
Protective effects of Notch1 signaling activation against high glucose-induced myocardial cell injury: Analysis of its mechanisms of action.
Molecular responses of radiation-induced liver damage in rats.
Effect of exenatide on the cardiac expression of adiponectin receptor 1 and NADPH oxidase subunits and heart function in streptozotocin-induced diabetic rats.
Resveratrol attenuates diabetic nephropathy via modulating angiogenesis.
Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats.
Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats.
Transplantation of endothelial progenitor cells alleviates renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction.
Ibarrola J, Xiang RR, Sun Z, Lu Q, Hill MA, Jaffe IZ
Clinical science (London, England : 1979) 2024 Mar 6;138(5):251-268
Clinical science (London, England : 1979) 2024 Mar 6;138(5):251-268
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Guo Y, Cui Y, Li Y, Jin X, Wang D, Lei M, Chen F, Liu Y, Xu J, Yao G, Zeng G, Chen X
Cancer communications (London, England) 2023 May;43(5):582-612
Cancer communications (London, England) 2023 May;43(5):582-612
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Cathepsin B/NLRP3/GSDMD axis-mediated macrophage pyroptosis induces inflammation and fibrosis in systemic sclerosis.
Liu C, Tang J, Liu S, Shen C, Zhou X, Lu J, Li M, Zhu L
Journal of dermatological science 2022 Dec;108(3):127-137
Journal of dermatological science 2022 Dec;108(3):127-137
TH5487, a small molecule inhibitor of OGG1, attenuates pulmonary fibrosis by NEDD4L-mediated OGG1 degradation.
Ling H, Song C, Fang Y, Yin Y, Wu Z, Wang Y, Xu Z, Gao S, Li A, Liu G
Chemico-biological interactions 2022 Aug 1;362:109999
Chemico-biological interactions 2022 Aug 1;362:109999
Ubiquitin-specific protease 2 regulates Ang Ⅱ-induced cardiac fibroblasts activation by up-regulating cyclin D1 and stabilizing β-catenin in vitro.
Xu Q, Liu M, Zhang F, Liu X, Ling S, Chen X, Gu J, Ou W, Liu S, Liu N
Journal of cellular and molecular medicine 2021 Jan;25(2):1001-1011
Journal of cellular and molecular medicine 2021 Jan;25(2):1001-1011
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.
Xu P, Yi Y, Luo Y, Liu Z, Xu Y, Cai J, Zeng Z, Liu A
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Arl4c promotes the growth and drug resistance of pancreatic cancer by regulating tumor-stromal interactions.
Chen X, Zhang Y, Qian W, Han L, Li W, Duan W, Wu Z, Wang Z, Ma Q
iScience 2021 Dec 17;24(12):103400
iScience 2021 Dec 17;24(12):103400
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway.
Li A, Xiao X, Feng ZL, Chen X, Liu LJ, Lin LG, Lu JJ, Zhang LL
Toxicology and applied pharmacology 2020 Jan 15;389:114882
Toxicology and applied pharmacology 2020 Jan 15;389:114882
Protective effects of Notch1 signaling activation against high glucose-induced myocardial cell injury: Analysis of its mechanisms of action.
Zhang J, Li B, Zheng Z, Kang T, Zeng M, Liu Y, Xia B
International journal of molecular medicine 2015 Sep;36(3):897-903
International journal of molecular medicine 2015 Sep;36(3):897-903
Molecular responses of radiation-induced liver damage in rats.
Cheng W, Xiao L, Ainiwaer A, Wang Y, Wu G, Mao R, Yang Y, Bao Y
Molecular medicine reports 2015 Apr;11(4):2592-600
Molecular medicine reports 2015 Apr;11(4):2592-600
Effect of exenatide on the cardiac expression of adiponectin receptor 1 and NADPH oxidase subunits and heart function in streptozotocin-induced diabetic rats.
Guo Z, Qi W, Yu Y, Du S, Wu J, Liu J
Diabetology & metabolic syndrome 2014 Feb 28;6(1):29
Diabetology & metabolic syndrome 2014 Feb 28;6(1):29
Resveratrol attenuates diabetic nephropathy via modulating angiogenesis.
Wen D, Huang X, Zhang M, Zhang L, Chen J, Gu Y, Hao CM
PloS one 2013;8(12):e82336
PloS one 2013;8(12):e82336
Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats.
Wang GG, Li W, Lu XH, Zhao X, Xu L
Croatian medical journal 2013 Apr;54(2):171-9
Croatian medical journal 2013 Apr;54(2):171-9
Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats.
Guo Z, Zhang R, Li J, Xu G
Cardiovascular diabetology 2012 Aug 8;11:94
Cardiovascular diabetology 2012 Aug 8;11:94
Transplantation of endothelial progenitor cells alleviates renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction.
Ma YY, Sun D, Li J, Yin ZC
Life sciences 2010 May 22;86(21-22):798-807
Life sciences 2010 May 22;86(21-22):798-807
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti- CTGF Picoband antibody, PB9541, Western blottingAll lanes: Anti CTGF (PB9541) at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Rat Thymus Tissue Lysate at 50ug Lane 3: HELA Whole Cell Lysate at 40ug Predicted bind size: 38KD Observed bind size: 38KD
- Additional image