MAB660

antibody from R&D Systems

Targeting: CCN2 CTGF, IGFBP8

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

MAB660

Provider

R&D Systems

Product name

Anti-Human CTGF/CCN2 C-Terminus Monoclonal Antibody (Clone 88430)

Antibody type

Monoclonal

Antigen

E. coli-derived recombinant human CTGF, Glu247-Ala349

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

NP_001892.1


Isotype

IgG

Vial size

500 µg

References

Submitted references

Curcumin inhibits TGF-β1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts.

Chen JT, Wang CY, Chen MH
Journal of the Formosan Medical Association = Taiwan yi zhi 2018 Dec;117(12):1115-1123

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Human gingiva transcriptome during wound healing.

Wang Y, Tatakis DN
Journal of clinical periodontology 2017 Apr;44(4):394-402

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Anti-CTGF single-chain variable fragment dimers inhibit human airway smooth muscle (ASM) cell proliferation by down-regulating p-Akt and p-mTOR levels.

Gao W, Cai L, Xu X, Fan J, Xue X, Yan X, Qu Q, Wang X, Zhang C, Wu G
PloS one 2014;9(12):e113980

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A physiological role for connective tissue growth factor in early wound healing.

Alfaro MP, Deskins DL, Wallus M, DasGupta J, Davidson JM, Nanney LB, A Guney M, Gannon M, Young PP
Laboratory investigation; a journal of technical methods and pathology 2013 Jan;93(1):81-95

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CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway.

Chen PS, Wang MY, Wu SN, Su JL, Hong CC, Chuang SE, Chen MW, Hua KT, Wu YL, Cha ST, Babu MS, Chen CN, Lee PH, Chang KJ, Kuo ML
Journal of cell science 2007 Jun 15;120(Pt 12):2053-65

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Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach.

Grønborg M, Kristiansen TZ, Iwahori A, Chang R, Reddy R, Sato N, Molina H, Jensen ON, Hruban RH, Goggins MG, Maitra A, Pandey A
Molecular & cellular proteomics : MCP 2006 Jan;5(1):157-71