orb317068

antibody from Biorbyt
Targeting: HLA-DRA HLA-DRA1
Provider product page for orb317068
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb317068 - Provider product page
Provider
Biorbyt
Product name
HLA-DR Antibody (MHC II)
Antibody type
Monoclonal
Description
This mAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
19-26.1 or MB-26.1
Vial size
20 ug
Storage
Store the HLA-DR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
HLA-DRA protein structure - orb317068 shown in red.