Antibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Other assay [2]
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- Product number
- MHLDR05 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- HLA-DR Monoclonal Antibody (TU36), APC
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Allophycocyanin (APC) is a stable and highly soluble phycobiliprotein that provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing exceptional quantum yields and molar extinction coefficients.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- TU36
- Vial size
- 500 µL
- Storage
- 4° C, store in dark
Submitted references Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton.
Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells.
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages.
Vestre K, Persiconi I, Borg Distefano M, Mensali N, Guadagno NA, Bretou M, Wälchli S, Arnold-Schrauf C, Bakke O, Dalod M, Lennon-Dumenil AM, Progida C
Journal of cell science 2021 Sep 15;134(18)
Journal of cell science 2021 Sep 15;134(18)
Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells.
Landsverk OJ, Ottesen AH, Berg-Larsen A, Appel S, Bakke O
Journal of leukocyte biology 2012 May;91(5):729-37
Journal of leukocyte biology 2012 May;91(5):729-37
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages.
Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):5215-20
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):5215-20
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
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- Experimental details
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- Submitted by
- Invitrogen Antibodies (provider)
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- Experimental details
- Fig. 2. Rab7b depletion does not affect DC maturation and antigen presentation ability. (A) MDDCs were transfected by electroporation with either control siRNA or Rab7b siRNA. 18 h (for immature DCs; imDCs) or 48 h (for LPS-DCs) after transfection the DCs were harvested, lysed and subjected to western blot analysis with antibodies against Rab7b and tubulin as a loading control. (B) Quantification of Rab7b levels in MDDCs silenced with control siRNA or Rab7b siRNA. The intensity of the bands from western blots was quantified using ImageQuant, and the level of Rab7b was normalized to the amount of tubulin. Data represent the mean+-s.d. of three independent experiments. *** P