A30434

antibody from Boster Biological Technology
Targeting: PRKN AR-JP, PARK2, parkin, PDJ
Provider product page for A30434
Western blot
Immunohistochemistry

Antibody data

Product number
A30434 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-Parkin PARK2 Antibody
Antibody type
Polyclonal
Description
Polyclonal antibody for PARK2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC. Reactive species: Human. PARK2 information: Molecular Weight: 51641 MW; Subcellular Localization: Cytoplasm, cytosol . Nucleus. Endoplasmic reticulum. Mitochondrion . Mainly localizes in the cytosol. Co-localizes with SYT11 in neutrites. Co-localizes with SNCAIP in brainstem Lewy bodies. Mitochondrial localization gradually increases with cellular growth. Also relocates to dysfunctional mitochondria that have lost the mitochondrial membrane potential; recruitment to mitochondria is PINK1- dependent; Tissue Specificity: Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons from kainate-mediated apoptosis. Found in serum (at protein level).
Reactivity
Human
Host
Rabbit
Vial size
100ul
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
PRKN protein structure - A30434 shown in red.