Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN358990 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) antibody
- Antibody type
- Polyclonal
- Antigen
- Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
This antibody is generated from rab
bits immunized with a KLH conjugate
d syntheticpeptide in the N-termina
l region of human Park2.- Vial size
- 0.1 mg
- Concentration
- 0.25 mg/mL
Submitted references Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations.
Parkin gene alterations in hepatocellular carcinoma.
N-myc regulates parkin expression.
Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.
Mutational analysis of parkin gene by denaturing high-performance liquid chromatography (DHPLC) in essential tremor.
Kumru H, Santamaria J, Tolosa E, Valldeoriola F, Muñoz E, Marti MJ, Iranzo A
Annals of neurology 2004 Oct;56(4):599-603
Annals of neurology 2004 Oct;56(4):599-603
Parkin gene alterations in hepatocellular carcinoma.
Wang F, Denison S, Lai JP, Philips LA, Montoya D, Kock N, Schüle B, Klein C, Shridhar V, Roberts LR, Smith DI
Genes, chromosomes & cancer 2004 Jun;40(2):85-96
Genes, chromosomes & cancer 2004 Jun;40(2):85-96
N-myc regulates parkin expression.
West AB, Kapatos G, O'Farrell C, Gonzalez-de-Chavez F, Chiu K, Farrer MJ, Maidment NT
The Journal of biological chemistry 2004 Jul 9;279(28):28896-902
The Journal of biological chemistry 2004 Jul 9;279(28):28896-902
Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.
Yao D, Gu Z, Nakamura T, Shi ZQ, Ma Y, Gaston B, Palmer LA, Rockenstein EM, Zhang Z, Masliah E, Uehara T, Lipton SA
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10810-4
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10810-4
Mutational analysis of parkin gene by denaturing high-performance liquid chromatography (DHPLC) in essential tremor.
Pigullo S, De Luca A, Barone P, Marchese R, Bellone E, Colosimo A, Scaglione C, Martinelli P, Di Maria E, Pizzuti A, Abbruzzese G, Dallapiccola B, Ajmar F, Mandich P
Parkinsonism & related disorders 2004 Aug;10(6):357-62
Parkinsonism & related disorders 2004 Aug;10(6):357-62
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- The anti-Parkin C-term Pab is used in Western blot to detect Parkin in mouse kidney tissue lysate.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- (LEFT)Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (RIGHT)Formalin-fixed and paraffin-embedded human testis tissue reacted with PARK2 (Parkin) antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.