orb317190

antibody from Biorbyt
Targeting: CD99 MIC2
Provider product page for orb317190
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb317190 - Provider product page
Provider
Biorbyt
Product name
CD99 Antibody Cocktail
Antibody type
Monoclonal
Description
Recognizes a sialoglycoprotein of 27-32kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32). Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors.
Reactivity
Human
Host
Mouse
Antibody clone number
12E7 + MIC2/877
Vial size
100 ul
Storage
Store the CD99 antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
CD99 protein structure - orb317190 shown in red.