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LearnTissue expression
Cell line expression
Protein structure
ATR
ATR serine/threonine kinaseFRP1, MEC1, SCKL, SCKL1
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| GeneTex |  GTX128145 |
30 references | Polyclonal |
WB
ICC
IP
IHC
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| Proteintech Group | 19787-1-AP |
16 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | NB100-308 |
18 references | Monoclonal |
WB
ICC
IP
FA
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| Invitrogen Antibodies | 19787-1-AP |
Polyclonal |
WB
ICC
IHC
OA
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| antibodies-online | ABIN151774 |
19 references | Monoclonal |
WB
ICC
IP
FA
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