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Cell line expression
Protein structure
EGFR
Epidermal growth factor receptorERBB, ERBB1
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-13269 |
71 references | Monoclonal |
WB
ICC
IP
IHC
FC
OA
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| Proteintech Group | 18986-1-AP |
147 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| R&D Systems | AF231 |
8 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| GeneTex | GTX100448 |
3 references | Polyclonal |
WB
ICC
IP
IHC
FC
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| Novus Biologicals | AF231 |
8 references | Polyclonal |
WB
ICC
IP
IHC
FC
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