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Cell line expression
Protein structure
NAE1
NEDD8 activating enzyme E1 subunit 1APP-BP1, APPBP1, ula-1
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  14863-1-AP |
1 references | Polyclonal |
WB
EL
IP
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| antibodies-online | ABIN359509 |
3 references | Polyclonal |
WB
EL
IHC
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| Abnova Corporation | PAB2845 |
3 references | Polyclonal |
WB
IHC
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| Atlas Antibodies | HPA041178 |
Polyclonal |
WB
IHC
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| Novus Biologicals | NBP1-92162 |
1 references | Polyclonal |
WB
IHC
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