25343-1-AP
antibody from Proteintech Group
Targeting: AGTR1
AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R
Antibody data
- Antibody Data
- Antigen structure
- References [27]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- 25343-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- AGTR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AGTR1 antibody (Cat. #25343-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice.
Fuyuan Xingnao Decoction Promotes Angiogenesis Through the Rab1/AT1R Pathway in Diabetes Mellitus Complicated With Cerebral Infarction.
A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
Paternal long-term PM2.5 exposure causes hypertension via increased renal AT1R expression and function in male offspring.
A potential impact of SARS-CoV-2 on pituitary glands and pituitary neuroendocrine tumors.
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Parental PM2 .5 exposure changes Th17/Treg cells in offspring, is associated with the elevation of blood pressure.
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
HUANGKUISIWUFANG inhibits pyruvate dehydrogenase to improve glomerular injury in anti-Thy1 nephritis model.
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors.
Aldosterone from endometrial glands is benefit for human decidualization.
Therapeutic effects of higenamine combined with [6]-gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function.
Puerarin Reduces Blood Pressure in Spontaneously Hypertensive Rats by Targeting eNOS.
Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system.
Endogenous hydrogen sulfide and ERK1/2-STAT3 signaling pathway may participate in the association between homocysteine and hypertension.
Comparing the effects of diethylhexyl phthalate and dibutyl phthalate exposure on hypertension in mice.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
The Kidney Injury Induced by Short-Term PM2.5 Exposure and the Prophylactic Treatment of Essential Oils in BALB/c Mice.
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Inhibition of tumor-promoting stroma to enforce subsequently targeting AT1R on tumor cells by pathological inspired micelles.
Gao M, Ma Y, Luo J, Li D, Jiang M, Jiang Q, Pi J, Chen R, Chen W, Zhang R, Zheng Y, Cui L
Frontiers in pharmacology 2021;12:618023
Frontiers in pharmacology 2021;12:618023
Fuyuan Xingnao Decoction Promotes Angiogenesis Through the Rab1/AT1R Pathway in Diabetes Mellitus Complicated With Cerebral Infarction.
Deng D, Qu Y, Sun L, Jia L, Bu J, Ye M, Chen Z, Geng Y, Zhou S, Fang B
Frontiers in pharmacology 2021;12:616165
Frontiers in pharmacology 2021;12:616165
A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.
Kim GJ, Mo H, Liu H, Wu Z, Chen S, Zheng J, Zhao X, Nucum D, Shortland J, Peng L, Elepano M, Tang B, Olson S, Paras N, Li H, Renslo AR, Arkin MR, Huang B, Lu B, Sirota M, Guo S
eLife 2021 Sep 22;10
eLife 2021 Sep 22;10
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P
Aging cell 2021 Oct;20(10):e13480
Aging cell 2021 Oct;20(10):e13480
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
Liu X, Deng R, Wei X, Wang Y, Weng J, Lao Y, Lu J, Xiong G, Li S
Bioscience reports 2021 Oct 29;41(10)
Bioscience reports 2021 Oct 29;41(10)
Paternal long-term PM2.5 exposure causes hypertension via increased renal AT1R expression and function in male offspring.
Hu C, Tao Y, Deng Y, Cai Q, Ren H, Yu C, Zheng S, Yang J, Zeng C
Clinical science (London, England : 1979) 2021 Nov 26;135(22):2575-2588
Clinical science (London, England : 1979) 2021 Nov 26;135(22):2575-2588
A potential impact of SARS-CoV-2 on pituitary glands and pituitary neuroendocrine tumors.
Gu WT, Zhou F, Xie WQ, Wang S, Yao H, Liu YT, Gao L, Wu ZB
Endocrine 2021 May;72(2):340-348
Endocrine 2021 May;72(2):340-348
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Feng X, Yu T, Zhang Y, Li L, Qu M, Wang J, Dong F, Zhang L, Wang F, Zhang F, Zhou X, Xu Z, Man D
Molecular nutrition & food research 2021 Jun;65(12):e2100072
Molecular nutrition & food research 2021 Jun;65(12):e2100072
Parental PM2 .5 exposure changes Th17/Treg cells in offspring, is associated with the elevation of blood pressure.
Pan K, Jiang S, Du X, Zeng X, Zhang J, Song L, Lei L, Zhou J, Kan H, Sun Q, Xie Y, Dong C, Zhao J
Environmental toxicology 2021 Jun;36(6):1152-1161
Environmental toxicology 2021 Jun;36(6):1152-1161
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Fu Y, Huang Y, Yang Z, Chen Y, Zheng J, Mao C, Li Z, Liu Z, Yu B, Li T, Wang M, Xu C, Zhou Y, Zhao G, Jia Y, Guo W, Jia X, Zhang T, Li L, Liu Z, Guo S, Ma M, Zhang H, Liu B, Du J, Wang W, Tang C, Gao P, Xu Q, Wang X, Liu J, Sun J, Kong W
Cell research 2021 Jul;31(7):773-790
Cell research 2021 Jul;31(7):773-790
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Liu C, Li X, Fu J, Chen K, Liao Q, Wang J, Chen C, Luo H, Jose PA, Yang Y, Yang J, Zeng C
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
Feng P, Wu Z, Liu H, Shen Y, Yao X, Li X, Shen Z
Neural plasticity 2020;2020:9076042
Neural plasticity 2020;2020:9076042
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
Chen Q, Yu WY, Zhang HH, Zhang SZ, Fang J, Wu F, Ying HZ, Yu CH
BioMed research international 2020;2020:8954513
BioMed research international 2020;2020:8954513
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
Du X, Zeng X, Zhang J, Pan K, Song L, Zhou J, Zhou L, Xie Y, Sun Q, Ge W, Chen R, Zhao J, Kan H
Ecotoxicology and environmental safety 2020 Oct 15;203:111044
Ecotoxicology and environmental safety 2020 Oct 15;203:111044
HUANGKUISIWUFANG inhibits pyruvate dehydrogenase to improve glomerular injury in anti-Thy1 nephritis model.
Lu T, Bian Y, Zhu Y, Guo M, Yang Y, Guo J, Gu C, Duan JA
Journal of ethnopharmacology 2020 May 10;253:112682
Journal of ethnopharmacology 2020 May 10;253:112682
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Su H, Chen X, Zhang Y, Qi L, He Y, Lv J, Zhang Y, Li X, Tang J, Xu Z
The Journal of endocrinology 2020 Jan;244(1):213-222
The Journal of endocrinology 2020 Jan;244(1):213-222
Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors.
Wu J, Chu Y, Jiang Z, Yu Q
Acta biochimica et biophysica Sinica 2020 Jan 2;52(1):38-48
Acta biochimica et biophysica Sinica 2020 Jan 2;52(1):38-48
Aldosterone from endometrial glands is benefit for human decidualization.
Li SY, Song Z, Yan YP, Li B, Song MJ, Liu YF, Yang ZS, Li MY, Liu AX, Quan S, Yang ZM
Cell death & disease 2020 Aug 13;11(8):679
Cell death & disease 2020 Aug 13;11(8):679
Therapeutic effects of higenamine combined with [6]-gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function.
Wen J, Zhang L, Wang J, Wang J, Wang L, Wang R, Li R, Liu H, Wei S, Li H, Zou W, Zhao Y
Journal of cellular and molecular medicine 2020 Apr;24(7):4036-4050
Journal of cellular and molecular medicine 2020 Apr;24(7):4036-4050
Puerarin Reduces Blood Pressure in Spontaneously Hypertensive Rats by Targeting eNOS.
Shi W, Yuan R, Chen X, Xin Q, Wang Y, Shang X, Cong W, Chen K
The American journal of Chinese medicine 2019;47(1):19-38
The American journal of Chinese medicine 2019;47(1):19-38
Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system.
Cui C, Xu P, Li G, Qiao Y, Han W, Geng C, Liao D, Yang M, Chen D, Jiang P
Redox biology 2019 Sep;26:101295
Redox biology 2019 Sep;26:101295
Endogenous hydrogen sulfide and ERK1/2-STAT3 signaling pathway may participate in the association between homocysteine and hypertension.
Shi L, Liu XY, Huang ZG, Ma ZY, Xi Y, Wang LY, Sun NL
Journal of geriatric cardiology : JGC 2019 Nov;16(11):822-834
Journal of geriatric cardiology : JGC 2019 Nov;16(11):822-834
Comparing the effects of diethylhexyl phthalate and dibutyl phthalate exposure on hypertension in mice.
Xie X, Deng T, Duan J, Ding S, Yuan J, Chen M
Ecotoxicology and environmental safety 2019 Jun 15;174:75-82
Ecotoxicology and environmental safety 2019 Jun 15;174:75-82
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
The Kidney Injury Induced by Short-Term PM2.5 Exposure and the Prophylactic Treatment of Essential Oils in BALB/c Mice.
Zhang Y, Li Q, Fang M, Ma Y, Liu N, Yan X, Zhou J, Li F
Oxidative medicine and cellular longevity 2018;2018:9098627
Oxidative medicine and cellular longevity 2018;2018:9098627
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Qin B, Wang Q, Lu Y, Li C, Hu H, Zhang J, Wang Y, Zhu J, Zhu Y, Xun Y, Wang S
Oxidative medicine and cellular longevity 2018;2018:1271864
Oxidative medicine and cellular longevity 2018;2018:1271864
Inhibition of tumor-promoting stroma to enforce subsequently targeting AT1R on tumor cells by pathological inspired micelles.
Zhu Y, Wen L, Shao S, Tan Y, Meng T, Yang X, Liu Y, Liu X, Yuan H, Hu F
Biomaterials 2018 Apr;161:33-46
Biomaterials 2018 Apr;161:33-46
No comments: Submit comment
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human heart tissue slide using 25343-1-AP( AGTR1 Antibody) at dilution of 1:50 (under 10x lens)
- Validation comment
- IHC
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human heart tissue slide using 25343-1-AP( AGTR1 Antibody) at dilution of 1:50 (under 40x lens)
- Validation comment
- IHC