Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [2]
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- Product number
- GTX37356 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX37356, RRID:AB_11175466
- Product name
- PGC1 alpha antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references Changes in Metabolism, Mitochondrial Function, and Oxidative Stress Between Female Rats Under Nonreproductive and 3 Reproductive Conditions.
Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
Laminar shear stress promotes mitochondrial homeostasis in endothelial cells.
A mitohormetic response to pro-oxidant exposure in the house mouse.
High activity before breeding improves reproductive performance by enhancing mitochondrial function and biogenesis.
Lactation has persistent effects on a mother's metabolism and mitochondrial function.
Pentoxifylline ameliorates non-alcoholic fatty liver disease in hyperglycaemic and dyslipidaemic mice by upregulating fatty acid β-oxidation.
CTRP9 induces mitochondrial biogenesis and protects high glucose-induced endothelial oxidative damage via AdipoR1 -SIRT1- PGC-1α activation.
Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction.
The neuroprotective role of metformin in advanced glycation end product treated human neural stem cells is AMPK-dependent.
Hyatt HW, Zhang Y, Hood WR, Kavazis AN
Reproductive sciences (Thousand Oaks, Calif.) 2019 Jan;26(1):114-127
Reproductive sciences (Thousand Oaks, Calif.) 2019 Jan;26(1):114-127
Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
Sajan MP, Lee MC, Foufelle F, Sajan J, Cleland C, Farese RV
Cellular signalling 2018 Mar;43:62-70
Cellular signalling 2018 Mar;43:62-70
Laminar shear stress promotes mitochondrial homeostasis in endothelial cells.
Wu LH, Chang HC, Ting PC, Wang DL
Journal of cellular physiology 2018 Jun;233(6):5058-5069
Journal of cellular physiology 2018 Jun;233(6):5058-5069
A mitohormetic response to pro-oxidant exposure in the house mouse.
Zhang Y, Humes F, Almond G, Kavazis AN, Hood WR
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jan 1;314(1):R122-R134
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jan 1;314(1):R122-R134
High activity before breeding improves reproductive performance by enhancing mitochondrial function and biogenesis.
Zhang Y, Brasher AL, Park NR, Taylor HA, Kavazis AN, Hood WR
The Journal of experimental biology 2018 Apr 6;221(Pt 7)
The Journal of experimental biology 2018 Apr 6;221(Pt 7)
Lactation has persistent effects on a mother's metabolism and mitochondrial function.
Hyatt HW, Zhang Y, Hood WR, Kavazis AN
Scientific reports 2017 Dec 7;7(1):17118
Scientific reports 2017 Dec 7;7(1):17118
Pentoxifylline ameliorates non-alcoholic fatty liver disease in hyperglycaemic and dyslipidaemic mice by upregulating fatty acid β-oxidation.
Ye JH, Chao J, Chang ML, Peng WH, Cheng HY, Liao JW, Pao LH
Scientific reports 2016 Sep 9;6:33102
Scientific reports 2016 Sep 9;6:33102
CTRP9 induces mitochondrial biogenesis and protects high glucose-induced endothelial oxidative damage via AdipoR1 -SIRT1- PGC-1α activation.
Cheng L, Li B, Chen X, Su J, Wang H, Yu S, Zheng Q
Biochemical and biophysical research communications 2016 Sep 2;477(4):685-691
Biochemical and biophysical research communications 2016 Sep 2;477(4):685-691
Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction.
Chiang MC, Cheng YC, Chen SJ, Yen CH, Huang RN
Experimental cell research 2016 Oct 1;347(2):322-31
Experimental cell research 2016 Oct 1;347(2):322-31
The neuroprotective role of metformin in advanced glycation end product treated human neural stem cells is AMPK-dependent.
Chung MM, Chen YL, Pei D, Cheng YC, Sun B, Nicol CJ, Yen CH, Chen HM, Liang YJ, Chiang MC
Biochimica et biophysica acta 2015 May;1852(5):720-31
Biochimica et biophysica acta 2015 May;1852(5):720-31
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western Blot of rat liver tissue using PGC1 alpha antibody.
- Validation comment
- WB
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- WB analysis of rat liver lysates using PGC1 alpha antibody.