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- Antibody Data
- Antigen structure
- References [38]
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- Product number
- 20658-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20658-1-AP, RRID:AB_2631201
- Product name
- PGC1a antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PGC1a antibody (Cat. #20658-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dietary succinate supplementation to maternal mice improves fetal brown adipose tissue development and thermogenesis of female offspring.
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1.
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.
Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.
Abdominal Massage Alleviates Skeletal Muscle Insulin Resistance by Regulating the AMPK/SIRT1/PGC-1α Signaling Pathway.
FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy.
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
ChREBP-β regulates thermogenesis in brown adipose tissue.
SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo.
Cardiomyocyte-specific loss of RNA polymerase II subunit 5-mediating protein causes myocardial dysfunction and heart failure.
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Effects of nitric oxide on steroidogenesis and apoptosis in goat luteinized granulosa cells.
Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.
Restoring mitochondrial biogenesis with metformin attenuates β-GP-induced phenotypic transformation of VSMCs into an osteogenic phenotype via inhibition of PDK4/oxidative stress-mediated apoptosis.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
Salvianolic Acid B Improves Mitochondrial Function in 3T3-L1 Adipocytes Through a Pathway Involving PPARγ Coactivator-1α (PGC-1α).
RIP140/PGC-1α axis involved in vitamin A-induced neural differentiation by increasing mitochondrial function.
Modified Si-Ni-San Decoction Ameliorates Central Fatigue by Improving Mitochondrial Biogenesis in the Rat Hippocampus.
SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain Injury.
Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link.
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Pro-metastatic signaling of the trans fatty acid elaidic acid is associated with lipid rafts.
Carbon black suppresses the osteogenesis of mesenchymal stem cells: the role of mitochondria.
The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.
Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients.
Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo.
MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice.
Zinc-alpha2-glycoprotein is involved in regulation of body weight through inhibition of lipogenic enzymes in adipose tissue.
Liu X, Chen Y, Zhao L, Tian Q, deAvila JM, Zhu MJ, Du M
The Journal of nutritional biochemistry 2022 Feb;100:108908
The Journal of nutritional biochemistry 2022 Feb;100:108908
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Wang R, Shi Z, Li J, Tang D, Qin S, Guo Y
Biological trace element research 2021 Nov 15;
Biological trace element research 2021 Nov 15;
Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1.
Yang M, Cui Y, Song J, Cui C, Wang L, Liang K, Wang C, Sha S, He Q, Hu H, Guo X, Zang N, Sun L, Chen L
Biochemical and biophysical research communications 2021 Mar 26;546:74-82
Biochemical and biophysical research communications 2021 Mar 26;546:74-82
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.
Zhao D, Pan Y, Yu N, Bai Y, Ma R, Mo F, Zuo J, Chen B, Jia Q, Zhang D, Liu J, Jiang G, Gao S
Royal Society open science 2021 Mar 17;8(3):200974
Royal Society open science 2021 Mar 17;8(3):200974
Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.
Wu L, Guo X, Wong SY, Lu P, Hartson SD, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, Chowanadisai W, Lin D
The Journal of nutritional biochemistry 2021 Feb;88:108542
The Journal of nutritional biochemistry 2021 Feb;88:108542
Abdominal Massage Alleviates Skeletal Muscle Insulin Resistance by Regulating the AMPK/SIRT1/PGC-1α Signaling Pathway.
Han Y, Lu Z, Chen S, Zhong C, Yan M, Wang H, Meng M, Liu M
Cell biochemistry and biophysics 2021 Dec;79(4):895-903
Cell biochemistry and biophysics 2021 Dec;79(4):895-903
FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway.
He ZH, Li M, Fang QJ, Liao FL, Zou SY, Wu X, Sun HY, Zhao XY, Hu YJ, Xu XX, Chen S, Sun Y, Chai RJ, Kong WJ
Autophagy 2021 Dec;17(12):4341-4362
Autophagy 2021 Dec;17(12):4341-4362
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy.
Wu H, Wei H, Zhang D, Sehgal SA, Zhang D, Wang X, Qin Y, Liu L, Chen Q
Redox biology 2020 Sep;36:101661
Redox biology 2020 Sep;36:101661
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Zhang J, Yang J, Yang N, Ma J, Lu D, Dong Y, Liang H, Liu D, Cang M
Lipids in health and disease 2020 Mar 13;19(1):39
Lipids in health and disease 2020 Mar 13;19(1):39
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo.
Yi X, Guo W, Shi Q, Yang Y, Zhang W, Chen X, Kang P, Chen J, Cui T, Ma J, Wang H, Guo S, Chang Y, Liu L, Jian Z, Wang L, Xiao Q, Li S, Gao T, Li C
Theranostics 2019;9(6):1614-1633
Theranostics 2019;9(6):1614-1633
Cardiomyocyte-specific loss of RNA polymerase II subunit 5-mediating protein causes myocardial dysfunction and heart failure.
Zhang J, Sheng J, Dong L, Xu Y, Yu L, Liu Y, Huang X, Wan S, Lan HY, Wang H
Cardiovascular research 2019 Sep 1;115(11):1617-1628
Cardiovascular research 2019 Sep 1;115(11):1617-1628
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Shi H, Yao R, Lian S, Liu P, Liu Y, Yang YY, Yang H, Li S
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q
Nature communications 2019 Mar 4;10(1):1034
Nature communications 2019 Mar 4;10(1):1034
Effects of nitric oxide on steroidogenesis and apoptosis in goat luteinized granulosa cells.
Guo YX, Zhang GM, Yao XL, Tong R, Cheng CY, Zhang TT, Wang ST, Yang H, Wang F
Theriogenology 2019 Mar 1;126:55-62
Theriogenology 2019 Mar 1;126:55-62
Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.
Song W, Luo Q, Zhang Y, Zhou L, Liu Y, Ma Z, Guo J, Huang Y, Cheng L, Meng Z, Li Z, Zhang B, Li S, Yee SW, Fan H, Li P, Giacomini KM, Chen L
PLoS biology 2019 Jan;17(1):e2006571
PLoS biology 2019 Jan;17(1):e2006571
Restoring mitochondrial biogenesis with metformin attenuates β-GP-induced phenotypic transformation of VSMCs into an osteogenic phenotype via inhibition of PDK4/oxidative stress-mediated apoptosis.
Ma WQ, Sun XJ, Wang Y, Zhu Y, Han XQ, Liu NF
Molecular and cellular endocrinology 2019 Jan 5;479:39-53
Molecular and cellular endocrinology 2019 Jan 5;479:39-53
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H
Molecular cell 2019 Dec 5;76(5):797-810.e10
Molecular cell 2019 Dec 5;76(5):797-810.e10
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
Kang Y, Li Y, Zhang T, Chi Y, Liu M
International journal of molecular medicine 2019 Aug;44(2):447-456
International journal of molecular medicine 2019 Aug;44(2):447-456
Salvianolic Acid B Improves Mitochondrial Function in 3T3-L1 Adipocytes Through a Pathway Involving PPARγ Coactivator-1α (PGC-1α).
Pan Y, Zhao W, Zhao D, Wang C, Yu N, An T, Mo F, Liu J, Miao J, Lv B, Gu Y, Gao S, Jiang G
Frontiers in pharmacology 2018;9:671
Frontiers in pharmacology 2018;9:671
RIP140/PGC-1α axis involved in vitamin A-induced neural differentiation by increasing mitochondrial function.
Mu Q, Yu W, Zheng S, Shi H, Li M, Sun J, Wang D, Hou X, Liu L, Wang X, Zhao Z, Liang R, Zhang X, Dong W, Zeng C, Guo J
Artificial cells, nanomedicine, and biotechnology 2018;46(sup1):806-816
Artificial cells, nanomedicine, and biotechnology 2018;46(sup1):806-816
Modified Si-Ni-San Decoction Ameliorates Central Fatigue by Improving Mitochondrial Biogenesis in the Rat Hippocampus.
Han C, Li F, Liu Y, Ma J, Yu X, Wu X, Zhang W, Li D, Chen D, Dai N, Lin B, Wu F, Mao M
Evidence-based complementary and alternative medicine : eCAM 2018;2018:9452127
Evidence-based complementary and alternative medicine : eCAM 2018;2018:9452127
SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain Injury.
Zhu Y, Wang H, Fang J, Dai W, Zhou J, Wang X, Zhou M
Oxidative medicine and cellular longevity 2018;2018:4783602
Oxidative medicine and cellular longevity 2018;2018:4783602
Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link.
Zhang Y, Wang C, Jin Y, Yang Q, Meng Q, Liu Q, Dai Y, Cai L, Liu Z, Liu K, Sun H
Oxidative medicine and cellular longevity 2018;2018:2876350
Oxidative medicine and cellular longevity 2018;2018:2876350
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
Wang C, Li L, Liu S, Liao G, Li L, Chen Y, Cheng J, Lu Y, Liu J
PloS one 2018;13(3):e0193473
PloS one 2018;13(3):e0193473
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Kou G, Li Z, Wu C, Liu Y, Hu Y, Guo L, Xu X, Zhou Z
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Qi X, Guo Y, Song Y, Yu C, Zhao L, Fang L, Kong D, Zhao J, Gao L
Diabetologia 2018 May;61(5):1180-1192
Diabetologia 2018 May;61(5):1180-1192
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Zhou Y, Du D, Liu S, Zhao M, Yuan Y, Li L, Chen Y, Lu Y, Cheng J, Liu J
Life sciences 2018 Jul 1;204:55-64
Life sciences 2018 Jul 1;204:55-64
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Wang Z, Yuan S, Li Y, Zhang Z, Xiao W, Tang D, Ye K, Liu Z, Wang C, Zheng Y, Nie H, Chen H
Biochemical pharmacology 2018 Apr;150:54-63
Biochemical pharmacology 2018 Apr;150:54-63
Pro-metastatic signaling of the trans fatty acid elaidic acid is associated with lipid rafts.
Kishi S, Fujiwara-Tani R, Luo Y, Kawahara I, Goto K, Fujii K, Ohmori H, Nakashima C, Sasaki T, Kuniyasu H
Oncology letters 2018 Apr;15(4):4423-4426
Oncology letters 2018 Apr;15(4):4423-4426
Carbon black suppresses the osteogenesis of mesenchymal stem cells: the role of mitochondria.
Shen Y, Wu L, Qin D, Xia Y, Zhou Z, Zhang X, Wu X
Particle and fibre toxicology 2018 Apr 12;15(1):16
Particle and fibre toxicology 2018 Apr 12;15(1):16
The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.
Wang XL, Li T, Li JH, Miao SY, Xiao XZ
Molecules (Basel, Switzerland) 2017 Sep 12;22(9)
Molecules (Basel, Switzerland) 2017 Sep 12;22(9)
Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients.
Li L, Wang C, Yang H, Liu S, Lu Y, Fu P, Liu J
Molecular bioSystems 2017 Oct 24;13(11):2392-2400
Molecular bioSystems 2017 Oct 24;13(11):2392-2400
Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo.
Shen R, Liu D, Hou C, Liu D, Zhao L, Cheng J, Wang D, Bai D
Food & function 2017 Oct 18;8(10):3636-3646
Food & function 2017 Oct 18;8(10):3636-3646
MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice.
Cheng L, Zhu Y, Han H, Zhang Q, Cui K, Shen H, Zhang J, Yan J, Prochownik E, Li Y
Cell death & disease 2017 Jul 13;8(7):e2916
Cell death & disease 2017 Jul 13;8(7):e2916
Zinc-alpha2-glycoprotein is involved in regulation of body weight through inhibition of lipogenic enzymes in adipose tissue.
Gong FY, Zhang SJ, Deng JY, Zhu HJ, Pan H, Li NS, Shi YF
International journal of obesity (2005) 2009 Sep;33(9):1023-30
International journal of obesity (2005) 2009 Sep;33(9):1023-30
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