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LearnNBP1-04676
antibody from Novus Biologicals
Targeting: PPARGC1A
PGC-1alpha, PGC1, PGC1A, PPARGC1
Western blot
Immunocytochemistry Immunoprecipitation Immunohistochemistry Flow cytometry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [112]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [2]
- Flow cytometry [2]
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- Product number
- NBP1-04676 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-04676, RRID:AB_1522118
- Product name
- Rabbit Polyclonal PGC1 alpha Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Goat, Hamster, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Hypoxia training improves hepatic steatosis partly by downregulation of CB1 receptor in obese mice.
Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons.
Effect of dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on gluconeogenesis in proximal renal tubules.
Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy.
Effect of methionine/choline-deficient diet and high-fat diet-induced steatohepatitis on mitochondrial homeostasis in mice.
MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma.
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models.
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.
QKI regulates adipose tissue metabolism by acting as a brake on thermogenesis and promoting obesity.
Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue.
LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells.
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia.
MiR-144 protects the heart from hyperglycemia-induced injury by regulating mitochondrial biogenesis and cardiomyocyte apoptosis.
SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle.
Long term hypoxia during gestation alters perirenal adipose tissue gene expression in the lamb.
NADPH oxidase 4 mediates the protective effects of physical activity against obesity-induced vascular dysfunction.
Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells.
Melatonin suppresses ischemia-induced fibrosis by regulating miR-149.
Methylated Vnn1 at promoter regions induces asthma occurrence via the PI3K/Akt/NFκB-mediated inflammation in IUGR mice.
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Artemether improves type 1 diabetic kidney disease by regulating mitochondrial function.
Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation.
Protection of Myocardial Ischemia-Reperfusion by Therapeutic Hypercapnia: a Mechanism Involving Improvements in Mitochondrial Biogenesis and Function.
p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer.
Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells.
Assessment of the Main Compounds of the Lipolytic System in Treadmill Running Rats: Different Response Patterns between the Right and Left Ventricle.
Effects of resveratrol on laminar shear stress-induced mitochondrial biogenesis in human vascular endothelial cells.
Effects of exercise training with short-duration intermittent hypoxia on endurance performance and muscle metabolism in well-trained mice.
SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding.
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis.
Secretory phospholipase A2 group IIA enhances the metabolic rate and increases glucose utilization in response to thyroid hormone.
Guggulsterone Activates Adipocyte Beiging through Direct Effects on 3T3-L1 Adipocytes and Indirect Effects Mediated through RAW264.7 Macrophages.
Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.
Recombinant human glucagon-like peptide-1 protects against chronic intermittent hypoxia by improving myocardial energy metabolism and mitochondrial biogenesis.
Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype.
Does butein affect adipogenesis?
Exercise regulates lipid droplet dynamics in normal and fatty liver.
Pioglitazone improves working memory performance when administered in chronic TBI.
Renoprotective effects of brown adipose tissue activation in diabetic mice.
Apolipoprotein E regulates mitochondrial function through the PGC-1α-sirtuin 3 pathway.
Overexpression of Sirtuin 1 protein in neurons prevents and reverses experimental diabetic neuropathy.
MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A.
The Therapeutic Implications of Tea Polyphenols Against Dopamine (DA) Neuron Degeneration in Parkinson's Disease (PD).
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro-elongation phenotype.
An In Vitro Study on Mitochondrial Compensatory Response Induced by Gliadin Peptides in Caco-2 Cells.
Modulation of cardiac vascular endothelial growth factor and PGC-1α with regular postexercise cold-water immersion of rats.
Functional role of ADAMTS5 in adiposity and metabolic health.
HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver.
Baicalin regulates SirT1/STAT3 pathway and restrains excessive hepatic glucose production.
Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis.
Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury.
Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling.
Cycling CD4+ T cells in HIV-infected immune nonresponders have mitochondrial dysfunction.
Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.
Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia.
Sirtuin signaling controls mitochondrial function in glycogen storage disease type Ia.
Berberine Protects Against Palmitate-Induced Apoptosis in Tubular Epithelial Cells by Promoting Fatty Acid Oxidation.
Short photoperiod reverses obesity in Siberian hamsters via sympathetically induced lipolysis and Browning in adipose tissue.
Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes.
Exercise decreases CLK2 in the liver of obese mice and prevents hepatic fat accumulation.
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation.
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy.
Mitochondrial glycerol 3-phosphate dehydrogenase promotes skeletal muscle regeneration.
Binding Efficacy and Thermogenic Efficiency of Pungent and Nonpungent Analogs of Capsaicin.
Network pharmacology-based identification of major component of Angelica sinensis and its action mechanism for the treatment of acute myocardial infarction.
Human adipose beiging in response to cold and mirabegron.
Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression.
Effects of Exposure to Ozone on the Ocular Surface in an Experimental Model of Allergic Conjunctivitis.
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis.
Bioenergetics of acquired cisplatin resistant H1299 non-small cell lung cancer and P31 mesothelioma cells.
Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts.
Possible role of mitochondrial injury in Caulis Aristolochia manshuriensis-induced chronic aristolochic acid nephropathy.
Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).
A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats.
Activation of AMPK attenuates LPS-induced acute lung injury by upregulation of PGC1α and SOD1.
Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.
Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner.
Evaluations of thyme extract effects in human normal bronchial and tracheal epithelial cell lines and in human lung cancer cell line.
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
Exercise Training Protects Against Acute Myocardial Infarction via Improving Myocardial Energy Metabolism and Mitochondrial Biogenesis.
Exercise Prevents Cardiac Injury and Improves Mitochondrial Biogenesis in Advanced Diabetic Cardiomyopathy with PGC-1α and Akt Activation.
Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes.
The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats.
Augmented Wnt signaling as a therapeutic tool to prevent ischemia/reperfusion injury in liver: Preclinical studies in a mouse model.
Exercise-mediated wall shear stress increases mitochondrial biogenesis in vascular endothelium.
Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice.
Cell surface lactate receptor GPR81 is crucial for cancer cell survival.
Mitochondrial quality control and age-associated arterial stiffening.
Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, simulating the effect of magnesium alloy degradation.
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
SIRT1 activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease.
Role of magnesium ions on osteogenic response in bone marrow stromal cells.
PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina.
Peroxisome proliferator-activated receptor δ agonist, HPP593, prevents renal necrosis under chronic ischemia.
ROS detoxification and proinflammatory cytokines are linked by p38 MAPK signaling in a model of mature astrocyte activation.
Increased HIF-1α and HIF-2α accumulation, but decreased microvascular density, in chronic hyperoxia and hypercapnia in the mouse cerebral cortex.
Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization.
SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells.
Age-associated molecular changes in the kidney in aged mice.
Drosha mediates destabilization of Lin28 mRNA targets.
Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance.
Nandrolone normalizes determinants of muscle mass and fiber type after spinal cord injury.
Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure.
Multiparity leads to obesity and inflammation in mothers and obesity in male offspring.
Decreased VEGF expression and microvascular density, but increased HIF-1 and 2α accumulation and EPO expression in chronic moderate hyperoxia in the mouse brain.
Dichotomous effects of VEGF-A on adipose tissue dysfunction.
Hypoxia-induced angiogenesis is delayed in aging mouse brain.
Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells.
Yang Q, Sun S, Liu W, Liu Q, Wang J
Biochemical and biophysical research communications 2020 May 7;525(3):639-645
Biochemical and biophysical research communications 2020 May 7;525(3):639-645
Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons.
Chandrasekaran K, Choi J, Arvas MI, Salimian M, Singh S, Xu S, Gullapalli RP, Kristian T, Russell JW
International journal of molecular sciences 2020 May 26;21(11)
International journal of molecular sciences 2020 May 26;21(11)
Effect of dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on gluconeogenesis in proximal renal tubules.
Kim JH, Ko HY, Wang HJ, Lee H, Yun M, Kang ES
Diabetes, obesity & metabolism 2020 Mar;22(3):373-382
Diabetes, obesity & metabolism 2020 Mar;22(3):373-382
Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy.
Zheng J, Akbari M, Schirmer C, Reynaert ML, Loyens A, Lefebvre B, Buée L, Croteau DL, Galas MC, Bohr VA
Acta neuropathologica communications 2020 Mar 4;8(1):25
Acta neuropathologica communications 2020 Mar 4;8(1):25
Effect of methionine/choline-deficient diet and high-fat diet-induced steatohepatitis on mitochondrial homeostasis in mice.
Arao Y, Kawai H, Kamimura K, Kobayashi T, Nakano O, Hayatsu M, Ushiki T, Terai S
Biochemical and biophysical research communications 2020 Jun 25;527(2):365-371
Biochemical and biophysical research communications 2020 Jun 25;527(2):365-371
MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma.
Harun-Or-Rashid M, Pappenhagen N, Zubricky R, Coughlin L, Jassim AH, Inman DM
Neurobiology of disease 2020 Jul;141:104944
Neurobiology of disease 2020 Jul;141:104944
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models.
Nguyen TTT, Zhang Y, Shang E, Shu C, Torrini C, Zhao J, Bianchetti E, Mela A, Humala N, Mahajan A, Harmanci AO, Lei Z, Maienschein-Cline M, Quinzii CM, Westhoff MA, Karpel-Massler G, Bruce JN, Canoll P, Siegelin MD
The Journal of clinical investigation 2020 Jul 1;130(7):3699-3716
The Journal of clinical investigation 2020 Jul 1;130(7):3699-3716
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.
Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL
Cell metabolism 2020 Jan 7;31(1):189-206.e8
Cell metabolism 2020 Jan 7;31(1):189-206.e8
QKI regulates adipose tissue metabolism by acting as a brake on thermogenesis and promoting obesity.
Lu H, Ye Z, Zhai Y, Wang L, Liu Y, Wang J, Zhang W, Luo W, Lu Z, Chen J
EMBO reports 2020 Jan 7;21(1):e47929
EMBO reports 2020 Jan 7;21(1):e47929
Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue.
Gao P, Jiang Y, Wu H, Sun F, Li Y, He H, Wang B, Lu Z, Hu Y, Wei X, Cui Y, He C, Wang L, Zheng H, Yang G, Liu D, Yan Z, Zhu Z
Diabetes 2020 Feb;69(2):165-180
Diabetes 2020 Feb;69(2):165-180
LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells.
Kalvala AK, Yerra VG, Kumar A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104695
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104695
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia.
Piers TM, Cosker K, Mallach A, Johnson GT, Guerreiro R, Hardy J, Pocock JM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2436-2450
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2436-2450
MiR-144 protects the heart from hyperglycemia-induced injury by regulating mitochondrial biogenesis and cardiomyocyte apoptosis.
Tao L, Huang X, Xu M, Yang L, Hua F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2173-2197
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2173-2197
SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle.
Dziewulska A, Dobosz AM, Dobrzyn A, Smolinska A, Kolczynska K, Ntambi JM, Dobrzyn P
Journal of cellular physiology 2020 Feb;235(2):1129-1140
Journal of cellular physiology 2020 Feb;235(2):1129-1140
Long term hypoxia during gestation alters perirenal adipose tissue gene expression in the lamb.
Myers DA, Singleton K, Hyatt K, Kaushal KM, Ducsay CA
Adipocyte 2020 Dec;9(1):223-233
Adipocyte 2020 Dec;9(1):223-233
NADPH oxidase 4 mediates the protective effects of physical activity against obesity-induced vascular dysfunction.
Brendel H, Shahid A, Hofmann A, Mittag J, Bornstein SR, Morawietz H, Brunssen C
Cardiovascular research 2020 Aug 1;116(10):1767-1778
Cardiovascular research 2020 Aug 1;116(10):1767-1778
Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells.
Bort A, Sánchez BG, de Miguel I, Mateos-Gómez PA, Diaz-Laviada I
Molecular biology reports 2020 Apr;47(4):2635-2647
Molecular biology reports 2020 Apr;47(4):2635-2647
Melatonin suppresses ischemia-induced fibrosis by regulating miR-149.
Han YS, Lee JH, Lee SH
Biochemical and biophysical research communications 2020 Apr 30;525(2):354-359
Biochemical and biophysical research communications 2020 Apr 30;525(2):354-359
Methylated Vnn1 at promoter regions induces asthma occurrence via the PI3K/Akt/NFκB-mediated inflammation in IUGR mice.
Xing Y, Wei H, Xiao X, Chen Z, Liu H, Tong X, Zhou W
Biology open 2020 Apr 28;9(4)
Biology open 2020 Apr 28;9(4)
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, Fu F, Li Y
Theranostics 2019;9(13):3687-3706
Theranostics 2019;9(13):3687-3706
Artemether improves type 1 diabetic kidney disease by regulating mitochondrial function.
Wang Y, Han P, Wang M, Weng W, Zhan H, Yu X, Yuan C, Shao M, Sun H
American journal of translational research 2019;11(6):3879-3889
American journal of translational research 2019;11(6):3879-3889
Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation.
Shao Y, Chen J, Freeman W, Dong LJ, Zhang ZH, Xu M, Qiu F, Du Y, Liu J, Li XR, Ma JX
Stem cells (Dayton, Ohio) 2019 Oct;37(10):1331-1343
Stem cells (Dayton, Ohio) 2019 Oct;37(10):1331-1343
Protection of Myocardial Ischemia-Reperfusion by Therapeutic Hypercapnia: a Mechanism Involving Improvements in Mitochondrial Biogenesis and Function.
Chi L, Wang N, Yang W, Wang Q, Zhao D, Sun T, Li W
Journal of cardiovascular translational research 2019 Oct;12(5):467-477
Journal of cardiovascular translational research 2019 Oct;12(5):467-477
p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer.
Chang HW, Kim MR, Lee HJ, Lee HM, Kim GC, Lee YS, Nam HY, Lee M, Jang HJ, Lee KE, Lee JC, Byun Y, Kim SW, Kim SY
Oncogene 2019 May;38(19):3729-3742
Oncogene 2019 May;38(19):3729-3742
Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells.
Zheng J, Croteau DL, Bohr VA, Akbari M
Nucleic acids research 2019 May 7;47(8):4086-4110
Nucleic acids research 2019 May 7;47(8):4086-4110
Assessment of the Main Compounds of the Lipolytic System in Treadmill Running Rats: Different Response Patterns between the Right and Left Ventricle.
Mikłosz A, Łukaszuk B, Baranowski M, Chabowski A, Górski J
International journal of molecular sciences 2019 May 24;20(10)
International journal of molecular sciences 2019 May 24;20(10)
Effects of resveratrol on laminar shear stress-induced mitochondrial biogenesis in human vascular endothelial cells.
Kim JS, Park JY
Journal of exercise nutrition & biochemistry 2019 Mar 31;23(1):7-12
Journal of exercise nutrition & biochemistry 2019 Mar 31;23(1):7-12
Effects of exercise training with short-duration intermittent hypoxia on endurance performance and muscle metabolism in well-trained mice.
Suzuki J
Physiological reports 2019 Jul;7(14):e14182
Physiological reports 2019 Jul;7(14):e14182
SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding.
Nguyen LT, Chen H, Zaky A, Pollock C, Saad S
The Journal of physiology 2019 Jan;597(2):467-480
The Journal of physiology 2019 Jan;597(2):467-480
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis.
Hasan-Olive MM, Lauritzen KH, Ali M, Rasmussen LJ, Storm-Mathisen J, Bergersen LH
Neurochemical research 2019 Jan;44(1):22-37
Neurochemical research 2019 Jan;44(1):22-37
Secretory phospholipase A2 group IIA enhances the metabolic rate and increases glucose utilization in response to thyroid hormone.
Kuefner MS, Deng X, Stephenson EJ, Pham K, Park EA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):738-749
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):738-749
Guggulsterone Activates Adipocyte Beiging through Direct Effects on 3T3-L1 Adipocytes and Indirect Effects Mediated through RAW264.7 Macrophages.
Miller CN, Samuels JS, Azhar Y, Parmar A, Shashidharamurthy R, Rayalam S
Medicines (Basel, Switzerland) 2019 Jan 31;6(1)
Medicines (Basel, Switzerland) 2019 Jan 31;6(1)
Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.
Manczak M, Kandimalla R, Yin X, Reddy PH
Human molecular genetics 2019 Jan 15;28(2):177-199
Human molecular genetics 2019 Jan 15;28(2):177-199
Recombinant human glucagon-like peptide-1 protects against chronic intermittent hypoxia by improving myocardial energy metabolism and mitochondrial biogenesis.
Tao L, Wang L, Yang X, Jiang X, Hua F
Molecular and cellular endocrinology 2019 Feb 5;481:95-103
Molecular and cellular endocrinology 2019 Feb 5;481:95-103
Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype.
Nahapetyan H, Moulis M, Grousset E, Faccini J, Grazide MH, Mucher E, Elbaz M, Martinet W, Vindis C
Cell death & disease 2019 Feb 11;10(2):119
Cell death & disease 2019 Feb 11;10(2):119
Does butein affect adipogenesis?
Hemmeryckx B, Vranckx C, Bauters D, Lijnen HR, Scroyen I
Adipocyte 2019 Dec;8(1):209-222
Adipocyte 2019 Dec;8(1):209-222
Exercise regulates lipid droplet dynamics in normal and fatty liver.
la Fuente FP, Quezada L, Sepúlveda C, Monsalves-Alvarez M, Rodríguez JM, Sacristán C, Chiong M, Llanos M, Espinosa A, Troncoso R
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Dec;1864(12):158519
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Dec;1864(12):158519
Pioglitazone improves working memory performance when administered in chronic TBI.
McGuire JL, Correll EA, Lowery AC, Rhame K, Anwar FN, McCullumsmith RE, Ngwenya LB
Neurobiology of disease 2019 Dec;132:104611
Neurobiology of disease 2019 Dec;132:104611
Renoprotective effects of brown adipose tissue activation in diabetic mice.
Cai YY, Zhang HB, Fan CX, Zeng YM, Zou SZ, Wu CY, Wang L, Fang S, Li P, Xue YM, Guan MP
Journal of diabetes 2019 Dec;11(12):958-970
Journal of diabetes 2019 Dec;11(12):958-970
Apolipoprotein E regulates mitochondrial function through the PGC-1α-sirtuin 3 pathway.
Yin J, Nielsen M, Carcione T, Li S, Shi J
Aging 2019 Dec 6;11(23):11148-11156
Aging 2019 Dec 6;11(23):11148-11156
Overexpression of Sirtuin 1 protein in neurons prevents and reverses experimental diabetic neuropathy.
Chandrasekaran K, Salimian M, Konduru SR, Choi J, Kumar P, Long A, Klimova N, Ho CY, Kristian T, Russell JW
Brain : a journal of neurology 2019 Dec 1;142(12):3737-3752
Brain : a journal of neurology 2019 Dec 1;142(12):3737-3752
MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A.
An SY, Zhang GM, Liu ZF, Zhou C, Yang PC, Wang F
Gene 2019 Aug 20;710:131-139
Gene 2019 Aug 20;710:131-139
The Therapeutic Implications of Tea Polyphenols Against Dopamine (DA) Neuron Degeneration in Parkinson's Disease (PD).
Zhou ZD, Xie SP, Saw WT, Ho PGH, Wang H, Lei Z, Yi Z, Tan EK
Cells 2019 Aug 16;8(8)
Cells 2019 Aug 16;8(8)
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder SS, Ge P, Shi R, Kim EJ, Liu A, Kim D, Quintin S, Jiang H, Kumar M, Yun SP, Kam TI, Mao X, Lee Y, Swing DA, Tessarollo L, Ko HS, Dawson VL, Dawson TM
Brain : a journal of neurology 2019 Aug 1;142(8):2380-2401
Brain : a journal of neurology 2019 Aug 1;142(8):2380-2401
Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro-elongation phenotype.
Axelrod CL, Fealy CE, Mulya A, Kirwan JP
Acta physiologica (Oxford, England) 2019 Apr;225(4):e13216
Acta physiologica (Oxford, England) 2019 Apr;225(4):e13216
An In Vitro Study on Mitochondrial Compensatory Response Induced by Gliadin Peptides in Caco-2 Cells.
Orlando A, Chimienti G, Pesce V, Fracasso F, Lezza AMS, Russo F
International journal of molecular sciences 2019 Apr 15;20(8)
International journal of molecular sciences 2019 Apr 15;20(8)
Modulation of cardiac vascular endothelial growth factor and PGC-1α with regular postexercise cold-water immersion of rats.
Al-Horani RA, Al-Trad B, Haifawi S
Journal of applied physiology (Bethesda, Md. : 1985) 2019 Apr 1;126(4):1110-1116
Journal of applied physiology (Bethesda, Md. : 1985) 2019 Apr 1;126(4):1110-1116
Functional role of ADAMTS5 in adiposity and metabolic health.
Bauters D, Bedossa P, Lijnen HR, Hemmeryckx B
PloS one 2018;13(1):e0190595
PloS one 2018;13(1):e0190595
HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver.
Arai T, Tanaka M, Goda N
Scientific reports 2018 Sep 21;8(1):14230
Scientific reports 2018 Sep 21;8(1):14230
Baicalin regulates SirT1/STAT3 pathway and restrains excessive hepatic glucose production.
Xu J, Li Y, Lou M, Xia W, Liu Q, Xie G, Liu L, Liu B, Yang J, Qin M
Pharmacological research 2018 Oct;136:62-73
Pharmacological research 2018 Oct;136:62-73
Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis.
Merz T, Wepler M, Nußbaum B, Vogt J, Calzia E, Wang R, Szabo C, Radermacher P, McCook O
Intensive care medicine experimental 2018 Oct 20;6(1):43
Intensive care medicine experimental 2018 Oct 20;6(1):43
Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury.
Basheer WA, Fu Y, Shimura D, Xiao S, Agvanian S, Hernandez DM, Hitzeman TC, Hong T, Shaw RM
JCI insight 2018 Oct 18;3(20)
JCI insight 2018 Oct 18;3(20)
Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling.
Cox CS, McKay SE, Holmbeck MA, Christian BE, Scortea AC, Tsay AJ, Newman LE, Shadel GS
Cell metabolism 2018 Nov 6;28(5):776-786.e5
Cell metabolism 2018 Nov 6;28(5):776-786.e5
Cycling CD4+ T cells in HIV-infected immune nonresponders have mitochondrial dysfunction.
Younes SA, Talla A, Pereira Ribeiro S, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive CL, Freeman ML, Panigrahi S, Zweig S, Balderas R, Margolis L, Douek DC, Anthony DD, Pandiyan P, Cameron M, Sieg SF, Calabrese LH, Rodriguez B, Lederman MM
The Journal of clinical investigation 2018 Nov 1;128(11):5083-5094
The Journal of clinical investigation 2018 Nov 1;128(11):5083-5094
Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.
Wang D, Sun H, Song G, Yang Y, Zou X, Han P, Li S
Molecular nutrition & food research 2018 May;62(9):e1700941
Molecular nutrition & food research 2018 May;62(9):e1700941
Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia.
Nobis S, Goichon A, Achamrah N, Guérin C, Azhar S, Chan P, Morin A, Bôle-Feysot C, do Rego JC, Vaudry D, Déchelotte P, Belmonte L, Coëffier M
Scientific reports 2018 May 8;8(1):7233
Scientific reports 2018 May 8;8(1):7233
Sirtuin signaling controls mitochondrial function in glycogen storage disease type Ia.
Cho JH, Kim GY, Mansfield BC, Chou JY
Journal of inherited metabolic disease 2018 May 8;
Journal of inherited metabolic disease 2018 May 8;
Berberine Protects Against Palmitate-Induced Apoptosis in Tubular Epithelial Cells by Promoting Fatty Acid Oxidation.
Sun J, Chen X, Liu T, Jiang X, Wu Y, Yang S, Hua W, Li Z, Huang H, Ruan X, Du X
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 12;24:1484-1492
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 12;24:1484-1492
Short photoperiod reverses obesity in Siberian hamsters via sympathetically induced lipolysis and Browning in adipose tissue.
Ryu V, Zarebidaki E, Albers HE, Xue B, Bartness TJ
Physiology & behavior 2018 Jun 1;190:11-20
Physiology & behavior 2018 Jun 1;190:11-20
Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes.
Unno Y, Yamamoto H, Takatsuki S, Sato Y, Kuranaga T, Yazawa K, Ono Y, Wakimoto T
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Jul;1863(7):772-782
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Jul;1863(7):772-782
Exercise decreases CLK2 in the liver of obese mice and prevents hepatic fat accumulation.
Muñoz VR, Gaspar RC, Kuga GK, Nakandakari SCBR, Baptista IL, Mekary RA, da Silva ASR, de Moura LP, Ropelle ER, Cintra DE, Pauli JR
Journal of cellular biochemistry 2018 Jul;119(7):5885-5892
Journal of cellular biochemistry 2018 Jul;119(7):5885-5892
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S
Cell metabolism 2018 Jan 9;27(1):85-100.e8
Cell metabolism 2018 Jan 9;27(1):85-100.e8
Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation.
Huang CL, Wang KC, Yang YC, Chiou CT, Tan CH, Lin YL, Huang NK
Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 Jan 15;39:75-84
Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 Jan 15;39:75-84
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2018 Jan 11;8(1):408
Scientific reports 2018 Jan 11;8(1):408
Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
Kim EN, Lim JH, Kim MY, Ban TH, Jang IA, Yoon HE, Park CW, Chang YS, Choi BS
Aging 2018 Jan 11;10(1):83-99
Aging 2018 Jan 11;10(1):83-99
Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy.
Lim JH, Kim HW, Kim MY, Kim TW, Kim EN, Kim Y, Chung S, Kim YS, Choi BS, Kim YS, Chang YS, Kim HW, Park CW
Cell death & disease 2018 Feb 15;9(3):270
Cell death & disease 2018 Feb 15;9(3):270
Mitochondrial glycerol 3-phosphate dehydrogenase promotes skeletal muscle regeneration.
Liu X, Qu H, Zheng Y, Liao Q, Zhang L, Liao X, Xiong X, Wang Y, Zhang R, Wang H, Tong Q, Liu Z, Dong H, Yang G, Zhu Z, Xu J, Zheng H
EMBO molecular medicine 2018 Dec;10(12)
EMBO molecular medicine 2018 Dec;10(12)
Binding Efficacy and Thermogenic Efficiency of Pungent and Nonpungent Analogs of Capsaicin.
Baskaran P, Covington K, Bennis J, Mohandass A, Lehmann T, Thyagarajan B
Molecules (Basel, Switzerland) 2018 Dec 4;23(12)
Molecules (Basel, Switzerland) 2018 Dec 4;23(12)
Network pharmacology-based identification of major component of Angelica sinensis and its action mechanism for the treatment of acute myocardial infarction.
Niu X, Zhang J, Ni J, Wang R, Zhang W, Sun S, Peng Y, Bai M, Zhang Z
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Human adipose beiging in response to cold and mirabegron.
Finlin BS, Memetimin H, Confides AL, Kasza I, Zhu B, Vekaria HJ, Harfmann B, Jones KA, Johnson ZR, Westgate PM, Alexander CM, Sullivan PG, Dupont-Versteegden EE, Kern PA
JCI insight 2018 Aug 9;3(15)
JCI insight 2018 Aug 9;3(15)
Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression.
Cho H, Rambout X, Gleghorn ML, Nguyen PQT, Phipps CR, Miyoshi K, Myers JR, Kataoka N, Fasan R, Maquat LE
Genes & development 2018 Apr 1;32(7-8):555-567
Genes & development 2018 Apr 1;32(7-8):555-567
Effects of Exposure to Ozone on the Ocular Surface in an Experimental Model of Allergic Conjunctivitis.
Lee H, Kim EK, Kim HY, Kim TI
PloS one 2017;12(1):e0169209
PloS one 2017;12(1):e0169209
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis.
Fakouri NB, Durhuus JA, Regnell CE, Angleys M, Desler C, Hasan-Olive MM, Martín-Pardillos A, Tsaalbi-Shtylik A, Thomsen K, Lauritzen M, Bohr VA, de Wind N, Bergersen LH, Rasmussen LJ
Scientific reports 2017 Oct 2;7(1):12480
Scientific reports 2017 Oct 2;7(1):12480
Bioenergetics of acquired cisplatin resistant H1299 non-small cell lung cancer and P31 mesothelioma cells.
Geoghegan F, Buckland RJ, Rogers ET, Khalifa K, O'Connor EB, Rooney MF, Behnam-Motlagh P, Nilsson TK, Grankvist K, Porter RK
Oncotarget 2017 Nov 7;8(55):94711-94725
Oncotarget 2017 Nov 7;8(55):94711-94725
Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts.
Chung E, Joiner HE, Skelton T, Looten KD, Manczak M, Reddy PH
Physiological reports 2017 Mar;5(5)
Physiological reports 2017 Mar;5(5)
Possible role of mitochondrial injury in Caulis Aristolochia manshuriensis-induced chronic aristolochic acid nephropathy.
Liu X, Wu J, Wang J, Fan J, Feng X, Yu X, Yang X
Drug and chemical toxicology 2017 Jan;40(1):115-124
Drug and chemical toxicology 2017 Jan;40(1):115-124
Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).
Kemter E, Fröhlich T, Arnold GJ, Wolf E, Wanke R
Scientific reports 2017 Feb 21;7:42970
Scientific reports 2017 Feb 21;7:42970
A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats.
Wang D, Chen J, Liu X, Zheng P, Song G, Yi T, Li S
Scientific reports 2017 Aug 23;7(1):9253
Scientific reports 2017 Aug 23;7(1):9253
Activation of AMPK attenuates LPS-induced acute lung injury by upregulation of PGC1α and SOD1.
Wang G, Song Y, Feng W, Liu L, Zhu Y, Xie X, Pan Y, Ke R, Li S, Li F, Yang L, Li M
Experimental and therapeutic medicine 2016 Sep;12(3):1551-1555
Experimental and therapeutic medicine 2016 Sep;12(3):1551-1555
Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.
Ivankovic D, Chau KY, Schapira AH, Gegg ME
Journal of neurochemistry 2016 Jan;136(2):388-402
Journal of neurochemistry 2016 Jan;136(2):388-402
Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner.
Biel TG, Lee S, Flores-Toro JA, Dean JW, Go KL, Lee MH, Law BK, Law ME, Dunn WA Jr, Zendejas I, Behrns KE, Kim JS
Cell death and differentiation 2016 Feb;23(2):279-90
Cell death and differentiation 2016 Feb;23(2):279-90
Evaluations of thyme extract effects in human normal bronchial and tracheal epithelial cell lines and in human lung cancer cell line.
Oliviero M, Romilde I, Beatrice MM, Matteo V, Giovanna N, Consuelo A, Claudio C, Giorgio S, Filippo M, Massimo N
Chemico-biological interactions 2016 Aug 25;256:125-33
Chemico-biological interactions 2016 Aug 25;256:125-33
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
De Andrade PB, Neff LA, Strosova MK, Arsenijevic D, Patthey-Vuadens O, Scapozza L, Montani JP, Ruegg UT, Dulloo AG, Dorchies OM
Frontiers in physiology 2015;6:254
Frontiers in physiology 2015;6:254
Exercise Training Protects Against Acute Myocardial Infarction via Improving Myocardial Energy Metabolism and Mitochondrial Biogenesis.
Tao L, Bei Y, Lin S, Zhang H, Zhou Y, Jiang J, Chen P, Shen S, Xiao J, Li X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(1):162-75
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(1):162-75
Exercise Prevents Cardiac Injury and Improves Mitochondrial Biogenesis in Advanced Diabetic Cardiomyopathy with PGC-1α and Akt Activation.
Wang H, Bei Y, Lu Y, Sun W, Liu Q, Wang Y, Cao Y, Chen P, Xiao J, Kong X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2159-68
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2159-68
Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes.
Kishida T, Ejima A, Yamamoto K, Tanaka S, Yamamoto T, Mazda O
Stem cell reports 2015 Oct 13;5(4):569-81
Stem cell reports 2015 Oct 13;5(4):569-81
The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats.
Hu J, Lang Y, Cao Y, Zhang T, Lu H
Neurochemical research 2015 Jul;40(7):1393-401
Neurochemical research 2015 Jul;40(7):1393-401
Augmented Wnt signaling as a therapeutic tool to prevent ischemia/reperfusion injury in liver: Preclinical studies in a mouse model.
Liu B, Zhang R, Tao G, Lehwald NC, Liu B, Koh Y, Sylvester KG
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2015 Dec;21(12):1533-42
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2015 Dec;21(12):1533-42
Exercise-mediated wall shear stress increases mitochondrial biogenesis in vascular endothelium.
Kim B, Lee H, Kawata K, Park JY
PloS one 2014;9(11):e111409
PloS one 2014;9(11):e111409
Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice.
Cho YR, Lim JH, Kim MY, Kim TW, Hong BY, Kim YS, Chang YS, Kim HW, Park CW
PloS one 2014;9(1):e83204
PloS one 2014;9(1):e83204
Cell surface lactate receptor GPR81 is crucial for cancer cell survival.
Roland CL, Arumugam T, Deng D, Liu SH, Philip B, Gomez S, Burns WR, Ramachandran V, Wang H, Cruz-Monserrate Z, Logsdon CD
Cancer research 2014 Sep 15;74(18):5301-10
Cancer research 2014 Sep 15;74(18):5301-10
Mitochondrial quality control and age-associated arterial stiffening.
LaRocca TJ, Hearon CM Jr, Henson GD, Seals DR
Experimental gerontology 2014 Oct;58:78-82
Experimental gerontology 2014 Oct;58:78-82
Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, simulating the effect of magnesium alloy degradation.
Yoshizawa S, Brown A, Barchowsky A, Sfeir C
Acta biomaterialia 2014 Jun;10(6):2834-42
Acta biomaterialia 2014 Jun;10(6):2834-42
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Li M, Lu Y, Hu Y, Zhai X, Xu W, Jing H, Tian X, Lin Y, Gao D, Yao J
Toxicology letters 2014 Jul 15;228(2):67-74
Toxicology letters 2014 Jul 15;228(2):67-74
SIRT1 activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease.
Khan RS, Dine K, Das Sarma J, Shindler KS
Acta neuropathologica communications 2014 Jan 2;2:3
Acta neuropathologica communications 2014 Jan 2;2:3
Role of magnesium ions on osteogenic response in bone marrow stromal cells.
Yoshizawa S, Brown A, Barchowsky A, Sfeir C
Connective tissue research 2014 Aug;55 Suppl 1:155-9
Connective tissue research 2014 Aug;55 Suppl 1:155-9
PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina.
Guo X, Dason ES, Zanon-Moreno V, Jiang Q, Nahirnyj A, Chan D, Flanagan JG, Sivak JM
The American journal of pathology 2014 Apr;184(4):1017-1029
The American journal of pathology 2014 Apr;184(4):1017-1029
Peroxisome proliferator-activated receptor δ agonist, HPP593, prevents renal necrosis under chronic ischemia.
Fedorova LV, Sodhi K, Gatto-Weis C, Puri N, Hinds TD Jr, Shapiro JI, Malhotra D
PloS one 2013;8(5):e64436
PloS one 2013;8(5):e64436
ROS detoxification and proinflammatory cytokines are linked by p38 MAPK signaling in a model of mature astrocyte activation.
Nahirnyj A, Livne-Bar I, Guo X, Sivak JM
PloS one 2013;8(12):e83049
PloS one 2013;8(12):e83049
Increased HIF-1α and HIF-2α accumulation, but decreased microvascular density, in chronic hyperoxia and hypercapnia in the mouse cerebral cortex.
Benderro GF, Tsipis CP, Sun X, Kuang Y, LaManna JC
Advances in experimental medicine and biology 2013;789:29-35
Advances in experimental medicine and biology 2013;789:29-35
Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization.
Xu R, Andres-Mateos E, Mejias R, MacDonald EM, Leinwand LA, Merriman DK, Fink RH, Cohn RD
Experimental neurology 2013 Sep;247:392-401
Experimental neurology 2013 Sep;247:392-401
SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells.
Khan RS, Fonseca-Kelly Z, Callinan C, Zuo L, Sachdeva MM, Shindler KS
Frontiers in cellular neuroscience 2012;6:63
Frontiers in cellular neuroscience 2012;6:63
Age-associated molecular changes in the kidney in aged mice.
Lim JH, Kim EN, Kim MY, Chung S, Shin SJ, Kim HW, Yang CW, Kim YS, Chang YS, Park CW, Choi BS
Oxidative medicine and cellular longevity 2012;2012:171383
Oxidative medicine and cellular longevity 2012;2012:171383
Drosha mediates destabilization of Lin28 mRNA targets.
Qiao C, Ma J, Xu J, Xie M, Ma W, Huang Y
Cell cycle (Georgetown, Tex.) 2012 Oct 1;11(19):3590-8
Cell cycle (Georgetown, Tex.) 2012 Oct 1;11(19):3590-8
Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance.
Salem AF, Whitaker-Menezes D, Howell A, Sotgia F, Lisanti MP
Cell cycle (Georgetown, Tex.) 2012 Nov 15;11(22):4174-80
Cell cycle (Georgetown, Tex.) 2012 Nov 15;11(22):4174-80
Nandrolone normalizes determinants of muscle mass and fiber type after spinal cord injury.
Wu Y, Zhao J, Zhao W, Pan J, Bauman WA, Cardozo CP
Journal of neurotrauma 2012 May 20;29(8):1663-75
Journal of neurotrauma 2012 May 20;29(8):1663-75
Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure.
Liu W, Singh R, Choi CS, Lee HY, Keramati AR, Samuel VT, Lifton RP, Shulman GI, Mani A
The Journal of biological chemistry 2012 Mar 2;287(10):7213-23
The Journal of biological chemistry 2012 Mar 2;287(10):7213-23
Multiparity leads to obesity and inflammation in mothers and obesity in male offspring.
Rebholz SL, Jones T, Burke KT, Jaeschke A, Tso P, D'Alessio DA, Woollett LA
American journal of physiology. Endocrinology and metabolism 2012 Feb 15;302(4):E449-57
American journal of physiology. Endocrinology and metabolism 2012 Feb 15;302(4):E449-57
Decreased VEGF expression and microvascular density, but increased HIF-1 and 2α accumulation and EPO expression in chronic moderate hyperoxia in the mouse brain.
Benderro GF, Sun X, Kuang Y, Lamanna JC
Brain research 2012 Aug 30;1471:46-55
Brain research 2012 Aug 30;1471:46-55
Dichotomous effects of VEGF-A on adipose tissue dysfunction.
Sun K, Wernstedt Asterholm I, Kusminski CM, Bueno AC, Wang ZV, Pollard JW, Brekken RA, Scherer PE
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 10;109(15):5874-9
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 10;109(15):5874-9
Hypoxia-induced angiogenesis is delayed in aging mouse brain.
Benderro GF, Lamanna JC
Brain research 2011 May 10;1389:50-60
Brain research 2011 May 10;1389:50-60
Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells.
Poomthavorn P, Wong SH, Higgins S, Werther GA, Russo VC
Endocrine-related cancer 2009 Sep;16(3):991-1004
Endocrine-related cancer 2009 Sep;16(3):991-1004
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Supportive validation
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- Experimental details
- Western Blot: PGC1 alpha Antibody [NBP1-04676] - Total protein from human adipose and skeletal muscle tissue, HeLa and A431 cells lines was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/mL PGC1 alpha Antibody (Molecular weight: 91 KDa) in 1% non-fat milk in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence
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- Novus Biologicals (provider)
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- Western Blot: PGC1 alpha Antibody [NBP1-04676] - Western Blot of total protein from murine skeletal muscle tissue using PGC1 alpha Antibody. Image from verified customer review.
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- Novus Biologicals (provider)
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- Western Blot: PGC1 alpha Antibody [NBP1-04676] - Mitochondrial content and biogenesis. Immunoblot analysis of PGC1 alpha in MEFs (n = 7; t = 5.764; df = 6). Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/s41598-017-12662-3), licensed under a CC-BY licence.
Supportive validation
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- Immunohistochemistry-Paraffin: PGC1 alpha Antibody [NBP1-04676] - Analysis of PGC1 alpha Antibody in mouse prostate using DAB with hematoxylin counterstain.
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- Novus Biologicals (provider)
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- Immunohistochemistry-Paraffin: PGC1 alpha Antibody [NBP1-04676] - Analysis of a FFPE section of mouse prostate using rabbit polyclonal PGC1 alpha Antibody at 1:200 dilution. The antibody generated an expected strong nuclear (punctate in some cells) and a weak cytoplasmic staining in the glandular cells lining of tubule-alveolar gland.
Supportive validation
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- Novus Biologicals (provider)
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- Flow (Intracellular): PGC1 alpha Antibody [NBP1-04676] - An intracellular stain was performed on HeLa cells with NBP1-04676AF647 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647.
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow (Intracellular): PGC1 alpha Antibody [NBP1-04676] - An intracellular stain was performed on HepG2 cells with PGC1 alpha Antibody and a matched isotype control. Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature, followed by Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody.
