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LearnM00236
antibody from Boster Biological Technology
Targeting: PPARGC1A
PGC-1alpha, PGC1, PGC1A, PPARGC1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
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- Product number
- M00236 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-PGC1 alpha PPARGC1A Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for PGC1 alpha/PPARGC1A detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human, Mouse, Rat PGC1 alpha/PPARGC1A information: Molecular Weight: 91027 MW; Subcellular Localization: Isoform 1: Nucleus. Nucleus, PML body; Tissue Specificity: Heart, skeletal muscle, liver and kidney. Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue. In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- AOBC-16
- Vial size
- 100ug/vial
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Rabbit Meat Extract Induces Browning in 3T3-L1 Adipocytes via the AMP-Activated Protein Kinase Pathway.
Subacute and low dose of tributyltin exposure leads to brown adipose abnormalities in male rats.
Arbutin Protects Retinal Pigment Epithelium Against Oxidative Stress by Modulating SIRT1/FOXO3a/PGC-1α/β Pathway.
The effects of Formoterol in preventing adipogenesis and obesity are mediated by PPARγ/C/EBPα axis and AMPK/PGC-1α pathway.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathway.
Sinapic Acid Promotes Browning of 3T3-L1 Adipocytes via p38 MAPK/CREB Pathway.
Effect of sitagliptin on expression of skeletal muscle peroxisome proliferator-activated receptor γ coactivator-1α and irisin in a rat model of type 2 diabetes mellitus.
PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells.
Expression and Secretion of an Atrial Natriuretic Peptide in Beige-Like 3T3-L1 Adipocytes.
Mitogen-activated protein kinase kinases promote mitochondrial biogenesis in part through inducing peroxisome proliferator-activated receptor γ coactivator-1β expression.
Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.
Structural activity relationship of flavonoids with estrogen-related receptor gamma.
Bae IS, Lee JA, Cho SH, Kim HW, Kim Y, Seo K, Cho HW, Lee MY, Chun JL, Kim KH
Foods (Basel, Switzerland) 2023 Oct 6;12(19)
Foods (Basel, Switzerland) 2023 Oct 6;12(19)
Subacute and low dose of tributyltin exposure leads to brown adipose abnormalities in male rats.
Merlo E, Zimerman J, Dos Santos FCF, Zanol JF, da Costa CS, Carneiro PH, Miranda-Alves L, Warner GR, Graceli JB
Toxicology letters 2023 Mar 1;376:26-38
Toxicology letters 2023 Mar 1;376:26-38
Arbutin Protects Retinal Pigment Epithelium Against Oxidative Stress by Modulating SIRT1/FOXO3a/PGC-1α/β Pathway.
Tang H, Du H, Kuang X, Huang H, Zeng J, Long C, Zhu B, Fu L, Wang H, Zhang Q, Lin S, Yan J, Shen H
Frontiers in genetics 2022;13:922807
Frontiers in genetics 2022;13:922807
The effects of Formoterol in preventing adipogenesis and obesity are mediated by PPARγ/C/EBPα axis and AMPK/PGC-1α pathway.
Zhang X, Che L, Shan J, Wang Y, Jia Y, Wu H
Bioscience, biotechnology, and biochemistry 2022 Jul 4;
Bioscience, biotechnology, and biochemistry 2022 Jul 4;
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Wang L, Wang X, Kong L, Li Y, Huang K, Wu J, Wang C, Sun H, Sun P, Gu J, Luo H, Liu K, Meng Q
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathway.
Cui YK, Hong YX, Wu WY, Han WM, Wu Y, Wu C, Li GR, Wang Y
European journal of pharmacology 2022 Apr 5;920:174858
European journal of pharmacology 2022 Apr 5;920:174858
Sinapic Acid Promotes Browning of 3T3-L1 Adipocytes via p38 MAPK/CREB Pathway.
Bae IS, Kim SH
BioMed research international 2020;2020:5753623
BioMed research international 2020;2020:5753623
Effect of sitagliptin on expression of skeletal muscle peroxisome proliferator-activated receptor γ coactivator-1α and irisin in a rat model of type 2 diabetes mellitus.
Liu Y, Xu F, Jiang P
The Journal of international medical research 2020 May;48(5):300060519885569
The Journal of international medical research 2020 May;48(5):300060519885569
PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells.
Liu Y, Bai H, Guo F, Thai PN, Luo X, Zhang P, Yang C, Feng X, Zhu D, Guo J, Liang P, Xu Z, Yang H, Lu X
Aging 2020 Apr 28;12(8):7411-7430
Aging 2020 Apr 28;12(8):7411-7430
Expression and Secretion of an Atrial Natriuretic Peptide in Beige-Like 3T3-L1 Adipocytes.
Bae IS, Kim SH
International journal of molecular sciences 2019 Dec 5;20(24)
International journal of molecular sciences 2019 Dec 5;20(24)
Mitogen-activated protein kinase kinases promote mitochondrial biogenesis in part through inducing peroxisome proliferator-activated receptor γ coactivator-1β expression.
Gao M, Wang J, Lu N, Fang F, Liu J, Wong CW
Biochimica et biophysica acta 2011 Jun;1813(6):1239-44
Biochimica et biophysica acta 2011 Jun;1813(6):1239-44
Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.
Liao X, Wang Y, Wong CW
British journal of pharmacology 2010 Oct;161(4):771-81
British journal of pharmacology 2010 Oct;161(4):771-81
Structural activity relationship of flavonoids with estrogen-related receptor gamma.
Huang Z, Fang F, Wang J, Wong CW
FEBS letters 2010 Jan 4;584(1):22-6
FEBS letters 2010 Jan 4;584(1):22-6
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