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- Antibody Data
- Antigen structure
- References [351]
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- Product number
- 66369-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- PGC1a antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated PGC1a antibody (Cat. #66369-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C1B2
- Vial size
- 20ul, 150ul
Submitted references Magnesium Ion-Doped Mesoporous Bioactive Glasses Loaded with Gallic Acid Against Myocardial Ischemia/Reperfusion Injury by Affecting the Biological Functions of Multiple Cells.
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice.
Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition.
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
Carcinoembryonic antigen potentiates non-small cell lung cancer progression via PKA-PGC-1ɑ axis.
Nickel induces mitochondrial damage in renal cells in vitro and in vivo through its effects on mitochondrial biogenesis, fusion, and fission.
NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis.
Collagen I protects human keratinocytes HaCaT against UVB injury via restoring PINK1/parkin-mediated mitophagy.
Pterostilbene protects against H(2) O(2) -induced oxidative stress by regulating GAS6/Axl signaling in HL-1 cells.
Hippocampal and gut AMPK activation attenuates enterocolitis-like symptoms and co-occurring depressive-like behavior in ulcerative colitis model mice: Involvement of brain-gut autophagy.
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway.
Exercise-inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue.
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Isolation of Calenduloside E from Achyranthes bidentata Blume and its effects on LPS/D-GalN-induced acute liver injury in mice by regulating the AMPK-SIRT3 signaling pathway.
PM(2.5) induces cardiac defects via AHR-SIRT1-PGC-1α mediated mitochondrial damage.
Pennogenin 3-O-β-Chacotrioside Attenuates Hypertrophied Lipid Accumulation by Enhancing Mitochondrial Oxidative Capacity.
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Electroacupuncture improves cognitive function in a rat model of mild traumatic brain injury by regulating the SIRT-1/PGC-1α/mitochondrial pathway.
Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway.
Knockdown of ACOT4 alleviates gluconeogenesis and lipid accumulation in hepatocytes.
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Cholesterol 25-hydroxylase prevents type 2 diabetes mellitus induced cardiomyopathy by alleviating cardiac lipotoxicity.
ZLN005 alleviates PBDE-47 induced impairment of mitochondrial translation and neurotoxicity through PGC-1α/ERRα axis.
Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel.
Menaquinone-4 alleviates hypoxic-ischemic brain damage in neonatal rats by reducing mitochondrial dysfunction via Sirt1-PGC-1α-TFAM signaling pathway.
Diosmetin ameliorates psoriasis-associated inflammation and keratinocyte hyperproliferation by modulation of PGC-1α / YAP signaling pathway.
Cornus officinalis Sieb. Et Zucc. attenuates Aβ(25-35)-induced mitochondrial damage and neuroinflammation in mice by modulating the ERK pathway.
Insights into the mechanism of action of pterostilbene against influenza A virus-induced acute lung injury.
Structural Variances in Curcumin Degradants: Impact on Obesity in Mice.
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Hydrangea paniculata coumarins alleviate adriamycin-induced renal lipotoxicity through activating AMPK and inhibiting C/EBPβ.
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle.
Synergistic effects of MFG-E8 and whey protein on mitigating d-galactose-induced sarcopenia through PI3K/AKT/PGC-1α and MAPK/ERK signaling pathways.
Genistein alleviates chronic heat stress-induced lipid metabolism disorder and mitochondrial energetic dysfunction by activating the GPR30-AMPK-PGC-1α signaling pathways in the livers of broiler chickens.
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Exercise-induced modulation of myokine irisin on muscle-bone unit in the rat model of post-traumatic osteoarthritis.
Dietary oleic acid intake increases the proportion of type 1 and 2X muscle fibers in mice.
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis.
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning.
Network pharmacology and experimental validation on yangjing zhongyu decoction against diminished ovarian reserve.
Promising anti-ovarian aging herbal formulation He's Yangchao promotes in vitro maturation of oocytes from advanced maternal age mice.
ACE2 activation alleviates sepsis-induced cardiomyopathy by promoting MasR-Sirt1-mediated mitochondrial biogenesis.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Microglia nuclear receptor corepressor 1 deficiency alleviates neuroinflammation in mice.
Alzheimer's Amyloid-β Accelerates Cell Senescence and Suppresses SIRT1 in Human Neural Stem Cells.
Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APP (SAA) knock-in mouse model of Alzheimer's disease.
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Sacubitril/valsartan ameliorates tubulointerstitial fibrosis by restoring mitochondrial homeostasis in diabetic kidney disease.
Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin†.
The use of a systems approach to increase NAD(+) in human participants.
Toxicity mechanism of acrolein on energy metabolism disorder and apoptosis in human ovarian granulosa cells.
Exerkine FNDC5/irisin-enriched exosomes promote proliferation and inhibit ferroptosis of osteoblasts through interaction with Caveolin-1.
Phenylsulfate-induced oxidative stress and mitochondrial dysfunction in podocytes are ameliorated by Astragaloside IV activation of the SIRT1/PGC1α /Nrf1 signaling pathway.
Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α.
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Nobiletin enhances mitochondrial function by regulating SIRT1/PGC-1α signaling in porcine oocytes during in vitro maturation.
Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia.
Chemerin affects blood lipid profile of high-fat diet male mice in sedentary and exercise states via glucose and lipid metabolism enzymes.
Corn peptides attenuate non-alcoholic fatty liver disease via PINK1/Parkin-mediated mitochondrial autophagy.
Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway.
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway.
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Exercise prevents fatal stress-induced myocardial injury in obese mice.
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Exosomal transfer leads to chemoresistance through oxidative phosphorylation-mediated stemness phenotype in colorectal cancer.
F-ATP synthase inhibitory factor 1 regulates metabolic reprogramming involving its interaction with c-Myc and PGC1α.
Evaluation of mitochondrial biogenesis and ROS generation in high-grade serous ovarian cancer.
Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α/SIRT3 Pathway to Prevent Western Diet-Induced Obesity.
Lactate Improves Long-term Cognitive Impairment Induced By Repeated Neonatal Sevoflurane Exposures Through SIRT1-mediated Regulation of Adult Hippocampal Neurogenesis and Synaptic Plasticity in Male Mice.
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Autoantibodies against the NineTeen complex and U5 RNP in systemic sclerosis.
Ginsenoside Rh4 delays skeletal muscle aging through SIRT1 pathway.
Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice.
Melatonin Restores Autophagic Flux by Activating the Sirt3/TFEB Signaling Pathway to Attenuate Doxorubicin-Induced Cardiomyopathy.
The neuroprotective effects of FG-4592, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, against oxidative stress induced by alpha-synuclein in N2a cells.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota.
Astragaloside IV-mediated inhibition of oxidative stress by upregulation of ghrelin in type 2 diabetes-induced cognitive impairment.
In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts.
Inhibition of mitochondrial fusion via SIRT1/PDK2/PARL axis breaks mitochondrial metabolic plasticity and sensitizes cancer cells to glucose restriction therapy.
Bezafibrate attenuates acute lung injury by preserving mitochondrial dynamics equilibrium in pulmonary epithelial cells.
Modified rougan decoction attenuates hepatocyte apoptosis through ameliorating mitochondrial dysfunction by upregulated SIRT1/PGC-1α signaling pathway.
Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats.
Transcriptome Analysis Revealed Potential Genes of Skeletal Muscle Thermogenesis in Mashen Pigs and Large White Pigs under Cold Stress.
Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α-FNDC5 axis.
Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca(2+) pathways.
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice.
SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of vidarabine against rotenone-induced neural cell injury.
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle.
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment.
Genistein mitigates senescence of bone marrow mesenchymal stem cells via ERRα-mediated mitochondrial biogenesis and mitophagy in ovariectomized rats.
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Sulfur mustard analog 2-chloroethyl ethyl sulfide increases triglycerides by activating DGAT1-dependent biogenesis and inhibiting PGC1ɑ-dependent fat catabolism in immortalized human bronchial epithelial cells.
Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity.
Knockdown of 11β-hydroxysteroid dehydrogenase type 1 alleviates LPS-induced myocardial dysfunction through the AMPK/SIRT1/PGC-1α pathway.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes.
The role of chemerin in the regulation of cGAS-STING pathway in gestational diabetes mellitus placenta.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT.
Effects of dietary l-theanine supplementation on pork quality and muscle fiber type transformation in finishing pigs.
Novel antioxidant peptides from MFGM protein Hydrolysates: Separation, identification and effects on Dexamethasone-induced mitochondrial dysfunction.
Mitochondrial citrate accumulation triggers senescence of alveolar epithelial cells contributing to pulmonary fibrosis in mice.
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Prevention of Glutamate-Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo.
Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis.
Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system.
Bavachin protects against diet-induced hepatic steatosis and obesity in mice.
HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway.
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway.
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Down-regulated Smyd1 participated in the inhibition of myoblast differentiation induced by cigarette smoke extract.
High-intensity interval training induces renal injury and fibrosis in type 2 diabetic mice.
Hydrogen sulfide alleviates heart failure with preserved ejection fraction in mice by targeting mitochondrial abnormalities via PGC-1α.
PGC-1α/NRF1-dependent cardiac mitochondrial biogenesis: A druggable pathway of calycosin against triptolide cardiotoxicity.
N-acetylcysteine delayed cadmium-induced chronic kidney injury by activating the sirtuin 1-P53 signaling pathway.
PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis.
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Dietary leucine and fish oil cooperatively regulate skeletal myofiber type transformation via the CaMKII signaling pathway of pigs.
PPARα agonist fenofibrate prevents postoperative cognitive dysfunction by enhancing fatty acid oxidation in mice.
Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, and mitochondrial dysfunction in adipose tissue.
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure.
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Phosphodiesterase 4B activation exacerbates pulmonary hypertension induced by intermittent hypoxia by regulating mitochondrial injury and cAMP/PKA/p-CREB/PGC-1α signaling.
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM Pathway.
Aerobic exercise inhibits renal EMT by promoting irisin expression in SHR.
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
Protective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis.
Urolithin A protects severe acute pancreatitis-associated acute cardiac injury by regulating mitochondrial fatty acid oxidative metabolism in cardiomyocytes.
Efficacy of creatine nitrate supplementation on redox status and mitochondrial function in pectoralis major muscle of preslaughter transported broilers.
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes.
Tamoxifen induced cardiac damage via the IL-6/p-STAT3/PGC-1α pathway.
Asperosaponin VI protects alcohol-induced hepatic steatosis and injury via regulating lipid metabolism and ER stress.
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway.
Histone H3 Acetylation Is Involved in Retinoid Acid-Induced Neural Differentiation through Increasing Mitochondrial Function.
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
[Linagliptin improves diabetic kidney disease in rats by promoting mitochondrial biogenesis through the AMPK/PGC-1α/TFAM pathway].
Didymin alleviates metabolic dysfunction-associated fatty liver disease (MAFLD) via the stimulation of Sirt1-mediated lipophagy and mitochondrial biogenesis.
Therapeutic Potential of Ginsenoside Rb1-PLGA Nanoparticles for Heart Failure Treatment via the ROS/PPARα/PGC1α Pathway.
Glycyrrhizic Acid Protects Glomerular Podocytes Induced by High Glucose by Modulating SNARK/AMPK Signaling Pathway.
Prolonged fluoride exposure induces spatial-memory deficit and hippocampal dysfunction by inhibiting small heat shock protein 22 in mice.
LDLR heterozygous deletion reduces hamster testicular cholesterol toxicity via AMPK/Sirt1/PGC-1α pathway.
Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway.
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca(2+) pathways in heart failure.
Resveratrol inhibits LPS-induced apoptosis in bovine mammary epithelial cells: the role of PGC1α-SIRT3 axis.
GAS6/Axl is associated with AMPK activation and attenuates H(2)O(2)-induced oxidative stress.
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway.
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Berberine Ameliorates Cognitive Disorder via GSK3β/PGC-1α Signaling in APP/PS1 Mice.
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Cryptotanshinone Protects against PCOS-Induced Damage of Ovarian Tissue via Regulating Oxidative Stress, Mitochondrial Membrane Potential, Inflammation, and Apoptosis via Regulating Ferroptosis.
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
An Energy Metabolism Study on the Efficacy of Naoxintong Capsules against Myocardial Infarction in a Rat Model.
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
∆nFGF1 Protects β-Cells against High Glucose-Induced Apoptosis via the AMPK/SIRT1/PGC-1α Axis.
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
Hippocampus-Based Mitochondrial Respiratory Function Decline Is Responsible for Perioperative Neurocognitive Disorders.
Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Mitochonic Acid-5 Inhibits Reactive Oxygen Species Production and Improves Human Chondrocyte Survival by Upregulating SIRT3-Mediated, Parkin-dependent Mitophagy.
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages.
Growth Hormone Receptor Controls Adipogenic Differentiation of Chicken Bone Marrow Mesenchymal Stem Cells by Affecting Mitochondrial Biogenesis and Mitochondrial Function.
Suppression of EZH2 inhibits TGF-β1-induced EMT in human retinal pigment epithelial cells.
Naringenin regulates gut microbiota and SIRT1/ PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome.
Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1α/Sirt3.
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis.
Hesperetin activated SIRT1 neutralizes cadmium effects on the early bovine embryo development.
Roles of HIF-1α/BNIP3 mediated mitophagy in mitochondrial dysfunction of letrozole-induced PCOS rats.
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Myocytic androgen receptor overexpression does not affect sex differences in adaptation to chronic endurance exercise.
SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways.
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Dihydromyricetin alters myosin heavy chain expression via AMPK signaling pathway in porcine myotubes.
The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression.
Indole-3-acetic acid improves the hepatic mitochondrial respiration defects by PGC1a up-regulation.
Insufficient sleep disrupts glucose metabolism during pregnancy by inhibiting PGC-1α.
Targeting Wnt/β-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITF.
Anti-fatigue effects of fermented soybean protein peptides in mice.
Piperine Improves Lipid Dysregulation by Modulating Circadian Genes Bmal1 and Clock in HepG2 Cells.
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
Sirtuin 6 affects glucose reabsorption and gluconeogenesis in type 1 diabetes via FoxO1.
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2.
Dihydromyricetin improves meat quality and promotes skeletal muscle fiber type transformations via AMPK signaling in growing-finishing pigs.
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
Involvement of Parkin-mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease-related sarcopenia.
The anti-fatigue activity of corn peptides and their effect on gut bacteria.
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway.
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Exerkine apelin reverses obesity-associated placental dysfunction by accelerating mitochondrial biogenesis in mice.
Inhibition of polycomb repressive complex 2 by targeting EED protects against cisplatin-induced acute kidney injury.
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Exposure to Bisphenol A Caused Hepatoxicity and Intestinal Flora Disorder in Rats.
Effect of Qingyangshen glycosides on social defeat mice model.
Caloric restriction and Roux-en-Y Gastric Bypass promote white adipose tissue browning in mice.
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Sodium butyrate ameliorates the cognitive impairment of Alzheimer's disease by regulating the metabolism of astrocytes.
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
d-Allulose Improves Endurance and Recovery from Exhaustion in Male C57BL/6J Mice.
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Arsenic causes mitochondrial biogenesis obstacles by inhibiting the AMPK/PGC-1α signaling pathway and also induces apoptosis and dysregulated mitophagy in the duck liver.
BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice.
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein.
circPTPN4 regulates myogenesis via the miR-499-3p/NAMPT axis.
Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway.
Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.
A plant-derived natural photosynthetic system for improving cell anabolism.
Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns.
Dietary L-theanine supplementation improves lipid metabolism and antioxidant capacity in weaning piglets.
Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs.
Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway.
miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes.
Cordycepin exhibits anti-fatigue effect via activating TIGAR/SIRT1/PGC-1α signaling pathway.
Exercise-derived peptide protects against pathological cardiac remodeling.
HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway.
Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner.
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
PPARGC1A Is a Moderator of Skeletal Muscle Development Regulated by miR-193b-3p.
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Circadian Clock Genes REV-ERBs Inhibits Granulosa Cells Apoptosis by Regulating Mitochondrial Biogenesis and Autophagy in Polycystic Ovary Syndrome.
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming.
Construction and Validation of a Combined Ferroptosis and Hypoxia Prognostic Signature for Hepatocellular Carcinoma.
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism.
ZLN005 protects against ischemia-reperfusion-induced kidney injury by mitigating oxidative stress through the restoration of mitochondrial fatty acid oxidation.
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK.
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR.
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.
A novel supplement with yeast β-glucan, prebiotic, minerals and Silybum marianum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice.
Effects of dietary ferulic acid supplementation on growth performance and skeletal muscle fiber type conversion in weaned piglets.
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Multiplexed quantitative evaluation on mitochondrial toxicity of tris (2,3-dibromopropyl) phosphate in hepatocyte.
DRD1 agonist A-68930 improves mitochondrial dysfunction and cognitive deficits in a streptozotocin-induced mouse model.
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Differentiation of THP-1 monocytes to macrophages increased mitochondrial DNA copy number but did not increase expression of mitochondrial respiratory proteins or mitochondrial transcription factor A.
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance.
Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation.
Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway.
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Embryonic exposure to hyper glucocorticoids suppresses brown fat development and thermogenesis via REDD1.
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK.
Bezafibrate prevents aging in in vitro-matured porcine oocytes.
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.
Immunotherapy against angiotensin II receptor ameliorated insulin resistance in a leptin receptor-dependent manner.
Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice.
Zinc-α2-glycoprotein promotes skeletal muscle lipid metabolism in cold-stressed mice.
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.
PGC1α regulates mitochondrial oxidative phosphorylation involved in cisplatin resistance in ovarian cancer cells via nucleo-mitochondrial transcriptional feedback.
20-HETE synthesis inhibition attenuates traumatic brain injury-induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC-1α pathway: A translational study.
Nobiletin activates thermogenesis of brown and white adipose tissue in high-fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway.
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease.
β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis.
Danqi Tablet () Regulates Energy Metabolism in Ischemic Heart Rat Model through AMPK/SIRT1-PGC-1α Pathway.
A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer's Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3.
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Network Pharmacology Approach to Explore the Potential Mechanisms of Jieduan-Niwan Formula Treating Acute-on-Chronic Liver Failure.
Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy.
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Postnatal growth retardation is associated with intestinal mucosa mitochondrial dysfunction and aberrant energy status in piglets.
SR18292 exerts potent antitumor effects in multiple myeloma via inhibition of oxidative phosphorylation.
MiR-23a-5p exacerbates intestinal ischemia-reperfusion injury by promoting oxidative stress via targeting PPAR alpha.
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Flavin adenine dinucleotide ameliorates hypertensive vascular remodeling via activating short chain acyl-CoA dehydrogenase.
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation.
A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility.
Effect of sitagliptin on expression of skeletal muscle peroxisome proliferator-activated receptor γ coactivator-1α and irisin in a rat model of type 2 diabetes mellitus.
Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway.
Resveratrol prevents benzo(a)pyrene-induced disruption of mitochondrial homeostasis via the AMPK signaling pathway in primary cultured neurons.
p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis.
Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs.
Myopathy reversion in mice after restauration of mitochondrial complex I.
Zinc-α2-glycoprotein promotes browning of white adipose tissue in cold-exposed male mice.
Si-Miao-Yong-An decoction preserves cardiac function and regulates GLC/AMPK/NF-κB and GLC/PPARα/PGC-1α pathways in diabetic mice.
Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.
Excessive Glucocorticoids During Pregnancy Impair Fetal Brown Fat Development and Predispose Offspring to Metabolic Dysfunctions.
(-)-Hydroxycitric acid regulates energy metabolism by activation of AMPK - PGC1α - NRF1 signal pathway in primary chicken hepatocytes.
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice.
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line.
Methane-Rich Saline: A Potential Resuscitation Fluid for Hemorrhagic Shock.
MOTS-c inhibits Osteolysis in the Mouse Calvaria by affecting osteocyte-osteoclast crosstalk and inhibiting inflammation.
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Role of the aryl hydrocarbon receptor signaling pathway in promoting mitochondrial biogenesis against oxidative damage in human melanocytes.
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
High-intensity interval training changes the expression of muscle RING-finger protein-1 and muscle atrophy F-box proteins and proteins involved in the mechanistic target of rapamycin pathway and autophagy in rat skeletal muscle.
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Maternal Eicosapentaenoic Acid Feeding Decreases Placental Lipid Deposition and Improves the Homeostasis of Oxidative Stress Through a Sirtuin-1 (SIRT1) Independent Manner.
Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy.
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
(-)-Hydroxycitric Acid Suppresses Lipid Droplet Accumulation and Accelerates Energy Metabolism via Activation of the Adiponectin-AMPK Signaling Pathway in Broiler Chickens.
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake.
Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway.
The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα.
Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice.
Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases in Vitro and in Vivo: Regulation of Redox Biology and Mitochondrial Function.
Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS.
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression.
The Role of Mitochondria in Methamphetamine-induced inhibitory effects on osteogenesis of Mesenchymal Stem Cells.
AMPK/α-Ketoglutarate Axis Regulates Intestinal Water and Ion Homeostasis in Young Pigs.
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Yu W, Ding J, Chen J, Jiang Y, Zhao J, Liu J, Zhou J, Liu J
International journal of nanomedicine 2024;19:347-366
International journal of nanomedicine 2024;19:347-366
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
Liu X, Jiang X, Hu J, Ding M, Lee SK, Korivi M, Qian Y, Li T, Wang L, Li W
Frontiers in nutrition 2024;11:1393343
Frontiers in nutrition 2024;11:1393343
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Xu H, Song X, Zhang X, Wang G, Cheng X, Zhang L, Wang Z, Li R, Ai C, Wang X, Pu L, Chen Z, Liu W
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice.
Liu H, Jiang L, Xu S, Wang C, Sun J
Drug and chemical toxicology 2024 Nov;47(6):1124-1138
Drug and chemical toxicology 2024 Nov;47(6):1124-1138
Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition.
Yang Z, Jiang J, Tan Y, Yang G, Chen M, Huang J, Liu J, Wei X, Wang S, Luo X, Han Z
Journal of physiology and biochemistry 2024 May;80(2):407-420
Journal of physiology and biochemistry 2024 May;80(2):407-420
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
He Y, Li R, Yu Y, Huang C, Xu Z, Wang T, Chen M, Huang H, Qi Z
Neurochemistry international 2024 May;175:105700
Neurochemistry international 2024 May;175:105700
Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
Zeng Q, Luo Y, Sang X, Liao M, Wen B, Hu Z, Sun M, Luo Z, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
Carcinoembryonic antigen potentiates non-small cell lung cancer progression via PKA-PGC-1ɑ axis.
Lei J, Wu L, Zhang N, Liu X, Zhang J, Kuang L, Chen J, Chen Y, Li D, Li Y
Molecular biomedicine 2024 May 24;5(1):19
Molecular biomedicine 2024 May 24;5(1):19
Nickel induces mitochondrial damage in renal cells in vitro and in vivo through its effects on mitochondrial biogenesis, fusion, and fission.
Yin H, Li X, Wang C, Li X, Liu J
Chemico-biological interactions 2024 May 1;394:110975
Chemico-biological interactions 2024 May 1;394:110975
NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis.
Zhou WY, Liu P, Xia YF, Shi YJ, Xu HY, Ding M, Yang QQ, Qian SW, Tang Y, Lu Y, Tang QQ, Liu Y
Molecular metabolism 2024 Mar;81:101891
Molecular metabolism 2024 Mar;81:101891
Collagen I protects human keratinocytes HaCaT against UVB injury via restoring PINK1/parkin-mediated mitophagy.
Zhu Y, Xiang W, He S, San Z, Liu W, Wu J, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Archives of biochemistry and biophysics 2024 Mar;753:109905
Archives of biochemistry and biophysics 2024 Mar;753:109905
Pterostilbene protects against H(2) O(2) -induced oxidative stress by regulating GAS6/Axl signaling in HL-1 cells.
Di W, Zhao A, Li X, Chen J, Dai Y, Li J, Lei W, Yang Y, Lu H
Cell biochemistry and function 2024 Mar;42(2):e3956
Cell biochemistry and function 2024 Mar;42(2):e3956
Hippocampal and gut AMPK activation attenuates enterocolitis-like symptoms and co-occurring depressive-like behavior in ulcerative colitis model mice: Involvement of brain-gut autophagy.
Takahashi K, Kurokawa K, Hong L, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Experimental neurology 2024 Mar;373:114671
Experimental neurology 2024 Mar;373:114671
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway.
Sun F, Sun Y, Wang X, Zhu J, Chen S, Yu Y, Zhu M, Xu W, Qian H
Bioactive materials 2024 Mar;33:444-459
Bioactive materials 2024 Mar;33:444-459
Exercise-inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue.
Shi H, Hao X, Sun Y, Zhao Y, Wang Y, Cao X, Gong Z, Ji S, Lu J, Yan Y, Yu X, Luo X, Wang J, Wang H
Acta physiologica (Oxford, England) 2024 Mar;240(3):e14103
Acta physiologica (Oxford, England) 2024 Mar;240(3):e14103
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Jia C, Wu Y, Gao F, Liu W, Li N, Chen Y, Sun L, Wang S, Yu C, Bao Y, Song Z
Free radical biology & medicine 2024 Mar;214:2-18
Free radical biology & medicine 2024 Mar;214:2-18
Isolation of Calenduloside E from Achyranthes bidentata Blume and its effects on LPS/D-GalN-induced acute liver injury in mice by regulating the AMPK-SIRT3 signaling pathway.
Guo P, Zeng M, Liu M, Zhang Y, Jia J, Zhang Z, Liang S, Zheng X, Feng W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155353
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155353
PM(2.5) induces cardiac defects via AHR-SIRT1-PGC-1α mediated mitochondrial damage.
Chen J, Zhang M, Aniagu S, Jiang Y, Chen T
Environmental toxicology and pharmacology 2024 Mar;106:104393
Environmental toxicology and pharmacology 2024 Mar;106:104393
Pennogenin 3-O-β-Chacotrioside Attenuates Hypertrophied Lipid Accumulation by Enhancing Mitochondrial Oxidative Capacity.
Yu S, Lee HM, Lee J, Hwang JT, Choi HK, Lee YG
International journal of molecular sciences 2024 Mar 4;25(5)
International journal of molecular sciences 2024 Mar 4;25(5)
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Yang Y, Qiu W, Xiao J, Sun J, Ren X, Jiang L
Journal of translational medicine 2024 Mar 26;22(1):309
Journal of translational medicine 2024 Mar 26;22(1):309
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway.
Zhang Y, Deng Q, Hong H, Qian Z, Wan B, Xia M
Journal of translational medicine 2024 Mar 25;22(1):304
Journal of translational medicine 2024 Mar 25;22(1):304
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Electroacupuncture improves cognitive function in a rat model of mild traumatic brain injury by regulating the SIRT-1/PGC-1α/mitochondrial pathway.
Jin B, Gao Y, Fu Y, Zhang S, Zhang K, Su Y
Chinese medical journal 2024 Mar 20;137(6):711-719
Chinese medical journal 2024 Mar 20;137(6):711-719
Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway.
Li S, Zhong H, Wang Z, Chen J, Huang Z, Zou T, You J
iScience 2024 Mar 15;27(3):109249
iScience 2024 Mar 15;27(3):109249
Knockdown of ACOT4 alleviates gluconeogenesis and lipid accumulation in hepatocytes.
Yuan Q, Zhang X, Yang X, Zhang Q, Wei X, Ding Z, Chen J, Hua H, Huang D, Xu Y, Wang X, Gao C, Liu S, Zhang H
Heliyon 2024 Mar 15;10(5):e27618
Heliyon 2024 Mar 15;10(5):e27618
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Zhu Y, Fang Y, Wang Y, Han D, Liu J, Tian L, Xu M, Wang Y, Cao F
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
Cholesterol 25-hydroxylase prevents type 2 diabetes mellitus induced cardiomyopathy by alleviating cardiac lipotoxicity.
Zhang J, Zhou H, Lei F, Jiang K, Liao Y, Huang F, Chen M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167158
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167158
ZLN005 alleviates PBDE-47 induced impairment of mitochondrial translation and neurotoxicity through PGC-1α/ERRα axis.
Tian Z, Li J, Tang H, Liu W, Hou H, Wang C, Li D, Chen G, Xia T, Wang A
Journal of hazardous materials 2024 Jun 5;471:134331
Journal of hazardous materials 2024 Jun 5;471:134331
Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel.
Huang T, Chen X, He J, Zheng P, Luo Y, Wu A, Yan H, Yu B, Chen D, Huang Z
eLife 2024 Jun 24;12
eLife 2024 Jun 24;12
Menaquinone-4 alleviates hypoxic-ischemic brain damage in neonatal rats by reducing mitochondrial dysfunction via Sirt1-PGC-1α-TFAM signaling pathway.
Feng X, Zheng Y, Mao N, Shen M, Chu L, Fang Y, Pang M, Wang Z, Lin Z
International immunopharmacology 2024 Jun 15;134:112257
International immunopharmacology 2024 Jun 15;134:112257
Diosmetin ameliorates psoriasis-associated inflammation and keratinocyte hyperproliferation by modulation of PGC-1α / YAP signaling pathway.
Yang D, Peng M, Fu F, Zhao W, Zhang B
International immunopharmacology 2024 Jun 15;134:112248
International immunopharmacology 2024 Jun 15;134:112248
Cornus officinalis Sieb. Et Zucc. attenuates Aβ(25-35)-induced mitochondrial damage and neuroinflammation in mice by modulating the ERK pathway.
Cao B, Zeng M, Hao F, Hao Z, Liang X, Zhang Z, Wu Y, Zhang Y, Wang R, Feng W, Zheng X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155709
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155709
Insights into the mechanism of action of pterostilbene against influenza A virus-induced acute lung injury.
Zhang Y, Li J, Qiu Z, Huang L, Yang S, Li J, Li K, Liang Y, Liu X, Chen Z, Li J, Zhou B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155534
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155534
Structural Variances in Curcumin Degradants: Impact on Obesity in Mice.
Koh YC, Hsu HW, Ho PY, Hsu KY, Lin WS, Nagabhushanam K, Ho CT, Pan MH
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14786-14798
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14786-14798
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Jiang T, Sun L, Wang Y, Zhang F, Guo J, Sun L, Jiang Y, Xue J, Duan J, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Hydrangea paniculata coumarins alleviate adriamycin-induced renal lipotoxicity through activating AMPK and inhibiting C/EBPβ.
Chen Y, Liu X, Ma J, Wang W, Li Z, Wu H, Lu Z, Zhang D, Zhang X, Zhang Y, Zhang S
Journal of ethnopharmacology 2024 Jul 15;329:118156
Journal of ethnopharmacology 2024 Jul 15;329:118156
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle.
Sato K, Satoshi Y, Miyauchi Y, Sato F, Kon R, Ikarashi N, Chiba Y, Hosoe T, Sakai H
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166877
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166877
Synergistic effects of MFG-E8 and whey protein on mitigating d-galactose-induced sarcopenia through PI3K/AKT/PGC-1α and MAPK/ERK signaling pathways.
Li H, Guan K, Wang R, Zhu A, Ma Y
Journal of dairy science 2024 Jan;107(1):9-23
Journal of dairy science 2024 Jan;107(1):9-23
Genistein alleviates chronic heat stress-induced lipid metabolism disorder and mitochondrial energetic dysfunction by activating the GPR30-AMPK-PGC-1α signaling pathways in the livers of broiler chickens.
Li L, Lu Z, Wang Y, Yang Y, Wang H, Ma H
Poultry science 2024 Jan;103(1):103251
Poultry science 2024 Jan;103(1):103251
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Xu L, Tang X, Yang L, Chang M, Xu Y, Chen Q, Lu C, Liu S, Jiang J
Molecular pain 2024 Jan-Dec;20:17448069241252654
Molecular pain 2024 Jan-Dec;20:17448069241252654
Exercise-induced modulation of myokine irisin on muscle-bone unit in the rat model of post-traumatic osteoarthritis.
Shang X, Hao X, Hou W, Liu J, Chi R, Deng X, Pan C, Xu T
Journal of orthopaedic surgery and research 2024 Jan 9;19(1):49
Journal of orthopaedic surgery and research 2024 Jan 9;19(1):49
Dietary oleic acid intake increases the proportion of type 1 and 2X muscle fibers in mice.
Komiya Y, Iseki S, Ochiai M, Takahashi Y, Yokoyama I, Suzuki T, Tatsumi R, Sawano S, Mizunoya W, Arihara K
Scientific reports 2024 Jan 8;14(1):755
Scientific reports 2024 Jan 8;14(1):755
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis.
Wang W, Chen S, Xu S, Liao G, Li W, Yang X, Li T, Zhang H, Huang H, Zhou Y, Pan H, Lin C
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117102
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117102
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning.
Wang Q, Su Y, Sun R, Xiong X, Guo K, Wei M, Yang G, Ru Y, Zhang Z, Li J, Zhang J, Qiao Q, Li X
Cell & bioscience 2024 Jan 20;14(1):12
Cell & bioscience 2024 Jan 20;14(1):12
Network pharmacology and experimental validation on yangjing zhongyu decoction against diminished ovarian reserve.
Liu J, Wei B, Ma Q, Shi D, Pan X, Liu Z, Li J, Zhao P
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117023
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117023
Promising anti-ovarian aging herbal formulation He's Yangchao promotes in vitro maturation of oocytes from advanced maternal age mice.
Yang L, Shang J, Wang H, Ma J, Wang L, Ma Y, Shuo J, Xu X, Cheng R, Duan X, Zhang Q
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116890
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116890
ACE2 activation alleviates sepsis-induced cardiomyopathy by promoting MasR-Sirt1-mediated mitochondrial biogenesis.
Wan TT, Li Y, Li JX, Xiao X, Liu L, Li HH, Guo SB
Archives of biochemistry and biophysics 2024 Feb;752:109855
Archives of biochemistry and biophysics 2024 Feb;752:109855
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
Microglia nuclear receptor corepressor 1 deficiency alleviates neuroinflammation in mice.
Qiu S, Xian Z, Chen J, Huang P, Wang H, Wang H, Xu J
Neuroscience letters 2024 Feb 6;822:137643
Neuroscience letters 2024 Feb 6;822:137643
Alzheimer's Amyloid-β Accelerates Cell Senescence and Suppresses SIRT1 in Human Neural Stem Cells.
Li R, Li Y, Zuo H, Pei G, Huang S, Hou Y
Biomolecules 2024 Feb 4;14(2)
Biomolecules 2024 Feb 4;14(2)
Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APP (SAA) knock-in mouse model of Alzheimer's disease.
Norambuena A, Sagar VK, Wang Z, Raut P, Feng Z, Wallrabe H, Pardo E, Kim T, Alam SR, Hu S, Periasamy A, Bloom GS
bioRxiv : the preprint server for biology 2024 Feb 4;
bioRxiv : the preprint server for biology 2024 Feb 4;
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Li Z, He R, Liu J, Jin X, Jiang B, Lao Y, Yang S
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
Sacubitril/valsartan ameliorates tubulointerstitial fibrosis by restoring mitochondrial homeostasis in diabetic kidney disease.
Zhang XJ, Liu CC, Li ZL, Ding L, Zhou Y, Zhang DJ, Zhang Y, Hou ST, Ma RX
Diabetology & metabolic syndrome 2024 Feb 10;16(1):40
Diabetology & metabolic syndrome 2024 Feb 10;16(1):40
Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin†.
Chae SA, Du M, Zhu MJ, Son JS
Biology of reproduction 2024 Feb 10;110(2):355-364
Biology of reproduction 2024 Feb 10;110(2):355-364
The use of a systems approach to increase NAD(+) in human participants.
Henderson JD, Quigley SNZ, Chachra SS, Conlon N, Ford D
npj aging 2024 Feb 1;10(1):7
npj aging 2024 Feb 1;10(1):7
Toxicity mechanism of acrolein on energy metabolism disorder and apoptosis in human ovarian granulosa cells.
Liu X, Li R, Xiu Z, Tang S, Duan Y
Toxicology 2024 Aug;506:153861
Toxicology 2024 Aug;506:153861
Exerkine FNDC5/irisin-enriched exosomes promote proliferation and inhibit ferroptosis of osteoblasts through interaction with Caveolin-1.
Tao L, Wang J, Wang K, Liu Q, Li H, Xu S, Gu C, Zhu Y
Aging cell 2024 Aug;23(8):e14181
Aging cell 2024 Aug;23(8):e14181
Phenylsulfate-induced oxidative stress and mitochondrial dysfunction in podocytes are ameliorated by Astragaloside IV activation of the SIRT1/PGC1α /Nrf1 signaling pathway.
Li L, Zou J, Zhou M, Li H, Zhou T, Liu X, Huang Q, Yang S, Xiang Q, Yu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117008
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117008
Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α.
Liu B, Xie D, Huang X, Jin S, Dai Y, Sun X, Li D, Bennett AM, Diano S, Huang Y
Diabetologia 2024 Apr;67(4):724-737
Diabetologia 2024 Apr;67(4):724-737
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
Yang M, Liu Y, Luo SL, Liu CB, Jiang N, Li CR, Zhao H, Han YC, Chen W, Li L, Sun L
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Nobiletin enhances mitochondrial function by regulating SIRT1/PGC-1α signaling in porcine oocytes during in vitro maturation.
Lee SH, Li XH, Lu QY, Zhan CL, Kim JD, Lee GH, Sim JM, Cui XS
Biochemical and biophysical research communications 2024 Apr 30;706:149747
Biochemical and biophysical research communications 2024 Apr 30;706:149747
Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia.
Ye L, Gao Y, Mok SWF, Liao W, Wang Y, Chen C, Yang L, Zhang J, Shi L
Journal of nanobiotechnology 2024 Apr 18;22(1):190
Journal of nanobiotechnology 2024 Apr 18;22(1):190
Chemerin affects blood lipid profile of high-fat diet male mice in sedentary and exercise states via glucose and lipid metabolism enzymes.
Jia Y, Yang Y, Qu J, Yin L, Wang X
Endocrine connections 2024 Apr 1;13(4)
Endocrine connections 2024 Apr 1;13(4)
Corn peptides attenuate non-alcoholic fatty liver disease via PINK1/Parkin-mediated mitochondrial autophagy.
Yao Z, Li X, Wang W, Ren P, Song S, Wang H, Xie Y, Li X, Li Z
Food & nutrition research 2023;67
Food & nutrition research 2023;67
Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway.
Jin X, He R, Lin Y, Liu J, Wang Y, Li Z, Liao Y, Yang S
Drug design, development and therapy 2023;17:3363-3383
Drug design, development and therapy 2023;17:3363-3383
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway.
Cao Y, Li Y, Han W, Jia X, Zhu P, Wei B, Cong X, Wang Z
Journal of inflammation research 2023;16:343-358
Journal of inflammation research 2023;16:343-358
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Yang D, Li J, Li Z, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Li W, Zhao D, Yang L
Frontiers in molecular neuroscience 2023;16:1163981
Frontiers in molecular neuroscience 2023;16:1163981
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Dun Y, Hu Z, You B, Du Y, Zeng L, Zhao Y, Liu Y, Wu S, Cui N, Yang F, Liu S
Frontiers in endocrinology 2023;14:1223423
Frontiers in endocrinology 2023;14:1223423
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Xu J, Zhang LW, Feng H, Tang Y, Fu SQ, Liu XM, Zhu XY
Frontiers in pharmacology 2023;14:1176443
Frontiers in pharmacology 2023;14:1176443
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Xu Y, Chen B, Yi J, Tian F, Liu Y, Ouyang Y, Yuan C, Liu B
Frontiers in pharmacology 2023;14:1137609
Frontiers in pharmacology 2023;14:1137609
Exosomal transfer leads to chemoresistance through oxidative phosphorylation-mediated stemness phenotype in colorectal cancer.
Deng J, Pan T, Lv C, Cao L, Li L, Zhou X, Li G, Li H, Vicencio JM, Xu Y, Wei F, Wang Y, Liu Z, Zhou G, Yin M
Theranostics 2023;13(14):5057-5074
Theranostics 2023;13(14):5057-5074
F-ATP synthase inhibitory factor 1 regulates metabolic reprogramming involving its interaction with c-Myc and PGC1α.
Guo L, Gu Z
Frontiers in oncology 2023;13:1207603
Frontiers in oncology 2023;13:1207603
Evaluation of mitochondrial biogenesis and ROS generation in high-grade serous ovarian cancer.
Koc ZC, Sollars VE, Bou Zgheib N, Rankin GO, Koc EC
Frontiers in oncology 2023;13:1129352
Frontiers in oncology 2023;13:1129352
Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α/SIRT3 Pathway to Prevent Western Diet-Induced Obesity.
Koh YC, Lin SJ, Hsu KY, Nagabhushanam K, Ho CT, Pan MH
Molecular nutrition & food research 2023 Sep;67(18):e2300370
Molecular nutrition & food research 2023 Sep;67(18):e2300370
Lactate Improves Long-term Cognitive Impairment Induced By Repeated Neonatal Sevoflurane Exposures Through SIRT1-mediated Regulation of Adult Hippocampal Neurogenesis and Synaptic Plasticity in Male Mice.
Qiu LL, Tan XX, Yang JJ, Ji MH, Zhang H, Zhao C, Xia JY, Sun J
Molecular neurobiology 2023 Sep;60(9):5273-5291
Molecular neurobiology 2023 Sep;60(9):5273-5291
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Cui Y, Zhang W, Yang P, Zhu S, Luo S, Li M
Free radical biology & medicine 2023 Sep;206:33-49
Free radical biology & medicine 2023 Sep;206:33-49
Autoantibodies against the NineTeen complex and U5 RNP in systemic sclerosis.
Vulsteke JB, Smith V, Bonroy C, Lenaerts JL, Derua R, Wuyts WA, Blockmans D, De Haes P, Piette Y, De Langhe E, Bossuyt X
Journal of autoimmunity 2023 Sep;139:103056
Journal of autoimmunity 2023 Sep;139:103056
Ginsenoside Rh4 delays skeletal muscle aging through SIRT1 pathway.
Zhu A, Duan Z, Chen Y, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154906
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154906
Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice.
Jian L, Gao X, Wang C, Sun X, Xu Y, Han R, Wang Y, Xu S, Ding L, Zhou J, Gu Y, Zhao Y, Yang Y, Yuan Y, Ye J, Zhang L
Biology direct 2023 Sep 4;18(1):54
Biology direct 2023 Sep 4;18(1):54
Melatonin Restores Autophagic Flux by Activating the Sirt3/TFEB Signaling Pathway to Attenuate Doxorubicin-Induced Cardiomyopathy.
Ma Y, Ma J, Lu L, Xiong X, Shao Y, Ren J, Yang J, Liu J
Antioxidants (Basel, Switzerland) 2023 Sep 4;12(9)
Antioxidants (Basel, Switzerland) 2023 Sep 4;12(9)
The neuroprotective effects of FG-4592, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, against oxidative stress induced by alpha-synuclein in N2a cells.
Fujimaki A, Ohuchi K, Takizawa S, Murakami T, Kurita H, Hozumi I, Wen X, Kitamura Y, Wu Z, Maekawa Y, Inden M
Scientific reports 2023 Sep 20;13(1):15629
Scientific reports 2023 Sep 20;13(1):15629
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota.
Li D, Cheng Y, Zeng X, Li Y, Xia Z, Yang X, Ren D
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13363-13375
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13363-13375
Astragaloside IV-mediated inhibition of oxidative stress by upregulation of ghrelin in type 2 diabetes-induced cognitive impairment.
Zhang RH, Cao SS, Shi Y, Wang X, Shi LL, Zhang YH, Han CJ, Wang B, Feng L, Liu JP
Naunyn-Schmiedeberg's archives of pharmacology 2023 Oct;396(10):2637-2650
Naunyn-Schmiedeberg's archives of pharmacology 2023 Oct;396(10):2637-2650
In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts.
Kamienieva I, Charzyńska A, Duszyński J, Malińska D, Szczepanowska J
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166787
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166787
Inhibition of mitochondrial fusion via SIRT1/PDK2/PARL axis breaks mitochondrial metabolic plasticity and sensitizes cancer cells to glucose restriction therapy.
Guo Y, Luo C, Sun Y, Guo W, Zhang R, Zhang X, Ke X, Wei L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115342
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115342
Bezafibrate attenuates acute lung injury by preserving mitochondrial dynamics equilibrium in pulmonary epithelial cells.
Song Y, Sun W, Li W, Li W
International immunopharmacology 2023 Oct;123:110751
International immunopharmacology 2023 Oct;123:110751
Modified rougan decoction attenuates hepatocyte apoptosis through ameliorating mitochondrial dysfunction by upregulated SIRT1/PGC-1α signaling pathway.
Wang W, Wu D, Ding J, Wang J, Meng J, Ming K, Li S, Qiu T, Liu J, Yang DA
Poultry science 2023 Oct;102(10):102992
Poultry science 2023 Oct;102(10):102992
Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats.
Yu F, Xing C, Fan Y, Liu Y, Su P, Yang Q, Dong Y, Hou Y, Pan S
Diabetology & metabolic syndrome 2023 Oct 30;15(1):221
Diabetology & metabolic syndrome 2023 Oct 30;15(1):221
Transcriptome Analysis Revealed Potential Genes of Skeletal Muscle Thermogenesis in Mashen Pigs and Large White Pigs under Cold Stress.
Li W, Chen Y, Zhang Y, Zhao N, Zhang W, Shi M, Zhao Y, Cai C, Lu C, Gao P, Guo X, Li B, Kim SW, Yang Y, Cao G
International journal of molecular sciences 2023 Oct 24;24(21)
International journal of molecular sciences 2023 Oct 24;24(21)
Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α-FNDC5 axis.
Hou YC, Liao MT, Tsai KW, Zheng CM, Chiu HW, Lu KC
Aging 2023 Oct 23;15(20):11532-11545
Aging 2023 Oct 23;15(20):11532-11545
Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca(2+) pathways.
Cui Z, Gu L, Liu T, Liu Y, Yu B, Kou J, Li F, Yang K
European journal of pharmacology 2023 Oct 15;957:176044
European journal of pharmacology 2023 Oct 15;957:176044
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice.
Kim Y, Li C, Gu C, Fang Y, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM
Nature communications 2023 Oct 14;14(1):6493
Nature communications 2023 Oct 14;14(1):6493
SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of vidarabine against rotenone-induced neural cell injury.
Li L, Zhang Y, Chen Z, Yao R, Xu Z, Xu C, He F, Pei H, Hao C
Heliyon 2023 Nov;9(11):e21695
Heliyon 2023 Nov;9(11):e21695
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
Sun W, Yue J, Xu T, Cui Y, Huang D, Shi H, Xiong J, Sun W, Yi Q
Heliyon 2023 Nov;9(11):e21282
Heliyon 2023 Nov;9(11):e21282
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Wang Z, Yang T, Zeng M, Wang Z, Chen Q, Chen J, Christian M, He Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle.
Liang J, Wei X, Hou W, Wang H, Ma R, Gao Y, Du Y, Zhang Q
Chinese medicine 2023 Nov 30;18(1):157
Chinese medicine 2023 Nov 30;18(1):157
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Liu W, Li F, Guo D, Du C, Zhao S, Li J, Yan Z, Hao J
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C
Nature communications 2023 Nov 18;14(1):7527
Nature communications 2023 Nov 18;14(1):7527
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Zheng P, Zhang Q, Ma W, Hu R, Gu Y, Bian Z, Yang D, Chen X, Wu H
European journal of pharmacology 2023 Nov 15;959:176085
European journal of pharmacology 2023 Nov 15;959:176085
Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment.
Hatae R, Kyewalabye K, Yamamichi A, Chen T, Phyu S, Chuntova P, Nejo T, Levine LS, Spitzer MH, Okada H
bioRxiv : the preprint server for biology 2023 Nov 15;
bioRxiv : the preprint server for biology 2023 Nov 15;
Genistein mitigates senescence of bone marrow mesenchymal stem cells via ERRα-mediated mitochondrial biogenesis and mitophagy in ovariectomized rats.
Li M, Yu Y, Xue K, Li J, Son G, Wang J, Qian W, Wang S, Zheng J, Yang C, Ge J
Redox biology 2023 May;61:102649
Redox biology 2023 May;61:102649
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Chen B, Wu J, Hu S, Liu Q, Yang H, You Y
Neurochemical research 2023 May;48(5):1504-1515
Neurochemical research 2023 May;48(5):1504-1515
Sulfur mustard analog 2-chloroethyl ethyl sulfide increases triglycerides by activating DGAT1-dependent biogenesis and inhibiting PGC1ɑ-dependent fat catabolism in immortalized human bronchial epithelial cells.
Ye F, Zeng Q, Dan G, Zhao Y, Yu W, Cheng J, Chen M, Wang B, Zhao J, Sai Y, Zou Z
Toxicology mechanisms and methods 2023 May;33(4):271-278
Toxicology mechanisms and methods 2023 May;33(4):271-278
Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity.
Fu Q, Li T, Zhang C, Ma X, Meng L, Liu L, Shao K, Wu G, Zhu X, Zhao X
Cell communication and signaling : CCS 2023 May 4;21(1):95
Cell communication and signaling : CCS 2023 May 4;21(1):95
Knockdown of 11β-hydroxysteroid dehydrogenase type 1 alleviates LPS-induced myocardial dysfunction through the AMPK/SIRT1/PGC-1α pathway.
Zhu D, Luo L, Zeng H, Zhang Z, Huang M, Zhou S
Journal of biomedical research 2023 May 29;37(4):303-314
Journal of biomedical research 2023 May 29;37(4):303-314
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes.
Boran T, Zengin OS, Seker Z, Akyildiz AG, Oztas E, Özhan G
Toxicology 2023 May 1;489:153489
Toxicology 2023 May 1;489:153489
The role of chemerin in the regulation of cGAS-STING pathway in gestational diabetes mellitus placenta.
Zhou X, Zhang H, Jiang Y, Wei L, Chen Y, Zhang J, Gao P, Zhu S, Fang C, Du Y, Su R, He M, Yu J, Wang S, Ding W, Feng L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22806
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22806
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT.
Li C, Zhu Y, Liu W, Xiang W, He S, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Archives of biochemistry and biophysics 2023 Mar 15;737:109553
Archives of biochemistry and biophysics 2023 Mar 15;737:109553
Effects of dietary l-theanine supplementation on pork quality and muscle fiber type transformation in finishing pigs.
Dai H, Chen X, Chen D, Yu B, He J, Chen H, Yan H, Zheng P, Luo Y, Huang Z
Journal of the science of food and agriculture 2023 Mar 15;103(4):2106-2115
Journal of the science of food and agriculture 2023 Mar 15;103(4):2106-2115
Novel antioxidant peptides from MFGM protein Hydrolysates: Separation, identification and effects on Dexamethasone-induced mitochondrial dysfunction.
Li H, Guan K, Liu M, Liu D, Wang W, Zhu A
Food chemistry 2023 Mar 1;403:134473
Food chemistry 2023 Mar 1;403:134473
Mitochondrial citrate accumulation triggers senescence of alveolar epithelial cells contributing to pulmonary fibrosis in mice.
Hong JR, Jin L, Zhang CY, Zhong WJ, Yang HH, Wang GM, Ma SC, Guan CX, Li Q, Zhou Y
Heliyon 2023 Jun;9(6):e17361
Heliyon 2023 Jun;9(6):e17361
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
Chae SA, Du M, Son JS, Zhu MJ
The Journal of physiology 2023 Jun;601(12):2371-2389
The Journal of physiology 2023 Jun;601(12):2371-2389
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Prevention of Glutamate-Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo.
Koh YC, Chok D, Chang CH, Wei CC, Wu CT, Cheng KC, Nagabhushanam K, Ho CT, Pan MH
Molecular nutrition & food research 2023 Jul;67(13):e2300139
Molecular nutrition & food research 2023 Jul;67(13):e2300139
Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis.
Zhong S, Chen W, Wang B, Gao C, Liu X, Song Y, Qi H, Liu H, Wu T, Wang R, Chen B
Redox biology 2023 Jul;63:102760
Redox biology 2023 Jul;63:102760
Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system.
Yoon H, Park SG, Kim HJ, Shin HR, Kim KT, Cho YD, Moon JI, Park MS, Kim WJ, Ryoo HM
Experimental & molecular medicine 2023 Jul;55(7):1531-1543
Experimental & molecular medicine 2023 Jul;55(7):1531-1543
Bavachin protects against diet-induced hepatic steatosis and obesity in mice.
Wei X, Lin L, Yuan QQ, Wang XY, Zhang Q, Zhang XM, Tang KC, Guo MY, Dong TY, Han W, Huang DK, Qi YL, Zhang M, Zhang HB
Acta pharmacologica Sinica 2023 Jul;44(7):1416-1428
Acta pharmacologica Sinica 2023 Jul;44(7):1416-1428
HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway.
Li BY, Peng WQ, Liu Y, Guo L, Tang QQ
Cell reports 2023 Jul 25;42(7):112731
Cell reports 2023 Jul 25;42(7):112731
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway.
Liu Y, Yang H, Luo N, Fu Y, Qiu F, Pan Z, Li X, Jian W, Yang X, Xue Q, Luo Y, Yu B, Liu Z
Journal of translational medicine 2023 Jul 20;21(1):486
Journal of translational medicine 2023 Jul 20;21(1):486
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Zhu Y, Han Y, Wang W, Liang G, Qi J
Journal of ethnopharmacology 2023 Jul 15;311:116286
Journal of ethnopharmacology 2023 Jul 15;311:116286
Down-regulated Smyd1 participated in the inhibition of myoblast differentiation induced by cigarette smoke extract.
Li F, Xu M, Miao J, Hu N, Wang Y, Wang L
Toxicology letters 2023 Jul 1;383:98-111
Toxicology letters 2023 Jul 1;383:98-111
High-intensity interval training induces renal injury and fibrosis in type 2 diabetic mice.
Zheng L, Qin R, Rao Z, Xiao W
Life sciences 2023 Jul 1;324:121740
Life sciences 2023 Jul 1;324:121740
Hydrogen sulfide alleviates heart failure with preserved ejection fraction in mice by targeting mitochondrial abnormalities via PGC-1α.
Huang S, Chen X, Pan J, Zhang H, Ke J, Gao L, Yu Chang AC, Zhang J, Zhang H
Nitric oxide : biology and chemistry 2023 Jul 1;136-137:12-23
Nitric oxide : biology and chemistry 2023 Jul 1;136-137:12-23
PGC-1α/NRF1-dependent cardiac mitochondrial biogenesis: A druggable pathway of calycosin against triptolide cardiotoxicity.
Qi XM, Qiao YB, Zhang YL, Wang AC, Ren JH, Wei HZ, Li QS
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113513
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113513
N-acetylcysteine delayed cadmium-induced chronic kidney injury by activating the sirtuin 1-P53 signaling pathway.
Dong W, Zhang K, Gong Z, Luo T, Li J, Wang X, Zou H, Song R, Zhu J, Ma Y, Liu G, Liu Z
Chemico-biological interactions 2023 Jan 5;369:110299
Chemico-biological interactions 2023 Jan 5;369:110299
PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis.
Tian Z, Li J, Song L, Xie L, Li D, Xia T, Wang A
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):123-134
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):123-134
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z
Nutrients 2023 Jan 3;15(1)
Nutrients 2023 Jan 3;15(1)
Dietary leucine and fish oil cooperatively regulate skeletal myofiber type transformation via the CaMKII signaling pathway of pigs.
Gong S, Yin Y, Han M, Guo L, Duan Y, Guo Q, Yin J, Li F
Food & function 2023 Jan 3;14(1):133-147
Food & function 2023 Jan 3;14(1):133-147
PPARα agonist fenofibrate prevents postoperative cognitive dysfunction by enhancing fatty acid oxidation in mice.
Liu T, Chen X, Wei Z, Han X, Liu Y, Ma Z, Xia T, Gu X
Translational neuroscience 2023 Jan 1;14(1):20220317
Translational neuroscience 2023 Jan 1;14(1):20220317
Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, and mitochondrial dysfunction in adipose tissue.
Qiu R, Wang S, Lin D, He Y, Huang S, Wu B, Li H, Wang M, Zheng F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22730
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22730
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure.
Wang Y, Tang T, Ren J, Zhao Y, Hou Y, Nie X
Aquatic toxicology (Amsterdam, Netherlands) 2023 Feb;255:106381
Aquatic toxicology (Amsterdam, Netherlands) 2023 Feb;255:106381
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Dai Z, Xia C, Zhao T, Wang H, Tian H, Xu O, Zhu X, Zhang J, Chen P
Materials today. Bio 2023 Feb;18:100512
Materials today. Bio 2023 Feb;18:100512
Phosphodiesterase 4B activation exacerbates pulmonary hypertension induced by intermittent hypoxia by regulating mitochondrial injury and cAMP/PKA/p-CREB/PGC-1α signaling.
Pan Z, Wu X, Zhang X, Hu K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114095
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114095
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Jiang X, Lu Z, Zhang Q, Yu J, Han D, Liu J, Li P, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM Pathway.
Han X, Wang J, Li R, Huang M, Yue G, Guan L, Deng Y, Cai W, Xu J
International journal of molecular sciences 2023 Feb 28;24(5)
International journal of molecular sciences 2023 Feb 28;24(5)
Aerobic exercise inhibits renal EMT by promoting irisin expression in SHR.
Luo M, Luo S, Xue Y, Chang Q, Yang H, Dong W, Zhang T, Cao S
iScience 2023 Feb 17;26(2):105990
iScience 2023 Feb 17;26(2):105990
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Zhao C, Gong Y, Zheng L, Zhao M
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
Lin S, Yang F, Hu M, Chen J, Chen G, Hu A, Li X, Fu D, Xing C, Xiong Z, Wu Y, Cao H
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
Protective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis.
Zhou J, Li M, Yu Z, Li C, Zhou L, Zhou X
Pharmaceutical biology 2023 Dec;61(1):80-88
Pharmaceutical biology 2023 Dec;61(1):80-88
Urolithin A protects severe acute pancreatitis-associated acute cardiac injury by regulating mitochondrial fatty acid oxidative metabolism in cardiomyocytes.
Yang Y, Hu Q, Kang H, Li J, Zhao X, Zhu L, Tang W, Wan M
MedComm 2023 Dec;4(6):e459
MedComm 2023 Dec;4(6):e459
Efficacy of creatine nitrate supplementation on redox status and mitochondrial function in pectoralis major muscle of preslaughter transported broilers.
Xu J, Xing T, Li J, Zhang L, Gao F
Animal biotechnology 2023 Dec;34(8):3988-3999
Animal biotechnology 2023 Dec;34(8):3988-3999
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Yan J, Xie J, Xu S, Guo Y, Ji K, Li C, Gao H, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes.
Wang GY, Qin SL, Zheng YN, Geng HJ, Chen L, Yao JH, Deng L
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Dec;15:88-98
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Dec;15:88-98
Tamoxifen induced cardiac damage via the IL-6/p-STAT3/PGC-1α pathway.
Meng T, Zhang D, Zhang Y, Tian P, Chen J, Liu A, Li Y, Song C, Zheng Y, Su G
International immunopharmacology 2023 Dec;125(Pt A):110978
International immunopharmacology 2023 Dec;125(Pt A):110978
Asperosaponin VI protects alcohol-induced hepatic steatosis and injury via regulating lipid metabolism and ER stress.
Wei L, Luo H, Jin Y, Shu Y, Wen C, Qin T, Yang X, Ma L, Liu Y, You Y, Zhou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155080
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155080
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway.
Mu F, Zhao J, Zhao M, Lin R, Liu K, Zhao S, Tao X, Li W, Dai Q, Xi M, Tang H, Wang J
The Journal of pharmacy and pharmacology 2023 Dec 8;75(12):1496-1508
The Journal of pharmacy and pharmacology 2023 Dec 8;75(12):1496-1508
Histone H3 Acetylation Is Involved in Retinoid Acid-Induced Neural Differentiation through Increasing Mitochondrial Function.
Zhang Y, Wang X, Mu Q, Hou X, Yu W, Guo J
Biomedicines 2023 Dec 8;11(12)
Biomedicines 2023 Dec 8;11(12)
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
Zhang L, Lin H, Yang X, Shi J, Sheng X, Wang L, Li T, Quan H, Zhai X, Li W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
[Linagliptin improves diabetic kidney disease in rats by promoting mitochondrial biogenesis through the AMPK/PGC-1α/TFAM pathway].
Wan L, Qian Y, Ni W, Lu Y, Li W, Pan Y, Chen W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Dec 20;43(12):2053-2060
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Dec 20;43(12):2053-2060
Didymin alleviates metabolic dysfunction-associated fatty liver disease (MAFLD) via the stimulation of Sirt1-mediated lipophagy and mitochondrial biogenesis.
Yang JW, Zou Y, Chen J, Cui C, Song J, Yang MM, Gao J, Hu HQ, Xia LQ, Wang LM, Lv XY, Chen L, Hou XG
Journal of translational medicine 2023 Dec 19;21(1):921
Journal of translational medicine 2023 Dec 19;21(1):921
Therapeutic Potential of Ginsenoside Rb1-PLGA Nanoparticles for Heart Failure Treatment via the ROS/PPARα/PGC1α Pathway.
Du L, Lu H, Wang Z, Liu C, Xiao Y, Guo Z, Li Y
Molecules (Basel, Switzerland) 2023 Dec 15;28(24)
Molecules (Basel, Switzerland) 2023 Dec 15;28(24)
Glycyrrhizic Acid Protects Glomerular Podocytes Induced by High Glucose by Modulating SNARK/AMPK Signaling Pathway.
Zhao TQ, Li Y, Zhang M, Zhao MC, Cao X, Hou SZ
Current medical science 2023 Aug;43(4):696-707
Current medical science 2023 Aug;43(4):696-707
Prolonged fluoride exposure induces spatial-memory deficit and hippocampal dysfunction by inhibiting small heat shock protein 22 in mice.
Xin J, Zhu B, Wang H, Zhang Y, Sun N, Cao X, Zheng L, Zhou Y, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Li F, Xia Y, Xu P, Ni X
Journal of hazardous materials 2023 Aug 15;456:131595
Journal of hazardous materials 2023 Aug 15;456:131595
LDLR heterozygous deletion reduces hamster testicular cholesterol toxicity via AMPK/Sirt1/PGC-1α pathway.
Bai Y, Hei N, Gao M, Dong X, Li M, Jiang S, Zhang L
Toxicology letters 2023 Aug 1;384:30-43
Toxicology letters 2023 Aug 1;384:30-43
Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway.
Yu D, Li J, Wang Y, Guo D, Zhang X, Chen M, Zhou Z
Drug development research 2023 Apr;84(2):211-225
Drug development research 2023 Apr;84(2):211-225
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
Wang Y, Chen X, Baker JS, Davison GW, Xu S, Zhou Y, Bao X
European journal of nutrition 2023 Apr;62(3):1453-1466
European journal of nutrition 2023 Apr;62(3):1453-1466
Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca(2+) pathways in heart failure.
Wan S, Cui Z, Wu L, Zhang F, Liu T, Hu J, Tian J, Yu B, Liu F, Kou J, Li F
Redox biology 2023 Apr;60:102610
Redox biology 2023 Apr;60:102610
Resveratrol inhibits LPS-induced apoptosis in bovine mammary epithelial cells: the role of PGC1α-SIRT3 axis.
Ouyang L, Tang H, Liu Z, Tian Y, Gao X, Peng T, Wang Z, Lan X, Shen W, Xiao D, Wan F, Liu L
In vitro cellular & developmental biology. Animal 2023 Apr;59(4):264-276
In vitro cellular & developmental biology. Animal 2023 Apr;59(4):264-276
GAS6/Axl is associated with AMPK activation and attenuates H(2)O(2)-induced oxidative stress.
Liang Z, Yang Y, Wu X, Lu C, Zhao H, Chen K, Zhao A, Li X, Xu J
Apoptosis : an international journal on programmed cell death 2023 Apr;28(3-4):485-497
Apoptosis : an international journal on programmed cell death 2023 Apr;28(3-4):485-497
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway.
Li Y, Liu Y, Chen Z, Tang K, Yang L, Jiang Y, Wang J, Huang P, Wang J, Zheng P, Song H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114319
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Chen H, Qi X, Guan K, Wang R, Li Q, Ma Y
Journal of dairy science 2023 Apr;106(4):2271-2288
Journal of dairy science 2023 Apr;106(4):2271-2288
Berberine Ameliorates Cognitive Disorder via GSK3β/PGC-1α Signaling in APP/PS1 Mice.
Yang M, Wang J
Journal of nutritional science and vitaminology 2022;68(3):228-235
Journal of nutritional science and vitaminology 2022;68(3):228-235
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Miao W, Chen M, Chen M, Cui C, Zhu Y, Luo X, Wu B
Mediators of inflammation 2022;2022:8373389
Mediators of inflammation 2022;2022:8373389
Cryptotanshinone Protects against PCOS-Induced Damage of Ovarian Tissue via Regulating Oxidative Stress, Mitochondrial Membrane Potential, Inflammation, and Apoptosis via Regulating Ferroptosis.
Liu H, Xie J, Fan L, Xia Y, Peng X, Zhou J, Ni X
Oxidative medicine and cellular longevity 2022;2022:8011850
Oxidative medicine and cellular longevity 2022;2022:8011850
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Ren C, Hu C, Wu Y, Li T, Zou A, Yu D, Shen T, Cai W, Yu J
Oxidative medicine and cellular longevity 2022;2022:5961123
Oxidative medicine and cellular longevity 2022;2022:5961123
An Energy Metabolism Study on the Efficacy of Naoxintong Capsules against Myocardial Infarction in a Rat Model.
Zhao J, Ouyang Y, Wang H, Lai H, Hu S, Tang L, Yang H, Wu H
Oxidative medicine and cellular longevity 2022;2022:3712500
Oxidative medicine and cellular longevity 2022;2022:3712500
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
Yin Z, Gao D, Du K, Han C, Liu Y, Wang Y, Gao X
Oxidative medicine and cellular longevity 2022;2022:2524832
Oxidative medicine and cellular longevity 2022;2022:2524832
∆nFGF1 Protects β-Cells against High Glucose-Induced Apoptosis via the AMPK/SIRT1/PGC-1α Axis.
Chen Q, Chen X, Jia Z, Du Y, Zhang S, Xu W, Pan B, Lou J, Zhou J, Zhou J, Sun J
Oxidative medicine and cellular longevity 2022;2022:1231970
Oxidative medicine and cellular longevity 2022;2022:1231970
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
Li Q, Tan JX, He Y, Bai F, Li SW, Hou YW, Ji LS, Gao YT, Zhang X, Zhou ZH, Yu Z, Fang M, Gao YQ, Li M
International journal of biological sciences 2022;18(4):1594-1611
International journal of biological sciences 2022;18(4):1594-1611
Hippocampus-Based Mitochondrial Respiratory Function Decline Is Responsible for Perioperative Neurocognitive Disorders.
He K, Zhang J, Zhang W, Wang S, Li D, Ma X, Wu X, Chai X, Liu Q
Frontiers in aging neuroscience 2022;14:772066
Frontiers in aging neuroscience 2022;14:772066
Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.
Zhu Z, Wang X, Song Z, Zuo X, Ma Y, Zhang Z, Ju C, Liang Z, Li K, Hu X, Wang Z
Frontiers in pharmacology 2022;13:991421
Frontiers in pharmacology 2022;13:991421
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154
Frontiers in endocrinology 2022;13:962154
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Ye Z, Ma J, Liu Y, Xu B, Dai X, Fu M, Tian T, Sui X, Mo F, Gao S, Zhao D, Zhang D
Frontiers in pharmacology 2022;13:950535
Frontiers in pharmacology 2022;13:950535
Mitochonic Acid-5 Inhibits Reactive Oxygen Species Production and Improves Human Chondrocyte Survival by Upregulating SIRT3-Mediated, Parkin-dependent Mitophagy.
Xin R, Xu Y, Long D, Mao G, Liao H, Zhang Z, Kang Y
Frontiers in pharmacology 2022;13:911716
Frontiers in pharmacology 2022;13:911716
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Guo K, Liu R, Jing R, Wang L, Li X, Zhang K, Fu M, Ye J, Hu Z, Zhao W, Xu N
Frontiers in pharmacology 2022;13:1036013
Frontiers in pharmacology 2022;13:1036013
AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages.
Xia L, Zhang C, Lv N, Liang Z, Ma T, Cheng H, Xia Y, Shi L
Theranostics 2022;12(6):2928-2947
Theranostics 2022;12(6):2928-2947
Growth Hormone Receptor Controls Adipogenic Differentiation of Chicken Bone Marrow Mesenchymal Stem Cells by Affecting Mitochondrial Biogenesis and Mitochondrial Function.
Zhao C, Hu B, Liao Z, Wei H, Zhao Y, Liang J, Luo W, Nie Q, Luo Q, Zhang D, Zhang X, Li H
Frontiers in cell and developmental biology 2022;10:827623
Frontiers in cell and developmental biology 2022;10:827623
Suppression of EZH2 inhibits TGF-β1-induced EMT in human retinal pigment epithelial cells.
Peng Y, Liao K, Tan F, Liang Y, Sun X, Cui Z, Ye B, Chen Z, Tang S, Chen J
Experimental eye research 2022 Sep;222:109158
Experimental eye research 2022 Sep;222:109158
Naringenin regulates gut microbiota and SIRT1/ PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome.
Wu YX, Yang XY, Han BS, Hu YY, An T, Lv BH, Lian J, Wang TY, Bao XL, Gao L, Jiang GJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113286
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113286
Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1α/Sirt3.
Wang D, Cao L, Zhou X, Wang G, Ma Y, Hao X, Fan H
Journal of hazardous materials 2022 Sep 5;437:129381
Journal of hazardous materials 2022 Sep 5;437:129381
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
Liu J, Shi D, Ma Q, Zhao P
Journal of ethnopharmacology 2022 Sep 15;295:115398
Journal of ethnopharmacology 2022 Sep 15;295:115398
CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis.
Ding M, Ma YJ, Du RQ, Zhou WY, Dou X, Yang QQ, Tang Y, Qian SW, Liu Y, Pan DN, Tang QQ, Liu Y
Diabetes 2022 Sep 1;71(9):1862-1879
Diabetes 2022 Sep 1;71(9):1862-1879
Hesperetin activated SIRT1 neutralizes cadmium effects on the early bovine embryo development.
Idrees M, Kumar V, Khan AM, Joo MD, Uddin Z, Lee KW, Kong IK
Theriogenology 2022 Sep 1;189:209-221
Theriogenology 2022 Sep 1;189:209-221
Roles of HIF-1α/BNIP3 mediated mitophagy in mitochondrial dysfunction of letrozole-induced PCOS rats.
Wang F, Han J, Wang X, Liu Y, Zhang Z
Journal of molecular histology 2022 Oct;53(5):833-842
Journal of molecular histology 2022 Oct;53(5):833-842
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Sun H, Shen L, Zhang P, Lin F, Ma J, Wu Y, Yu H, Sun L
International journal of molecular sciences 2022 Oct 4;23(19)
International journal of molecular sciences 2022 Oct 4;23(19)
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Zhang S, Li J, Shi X, Tan X, Si Q
Food & function 2022 Oct 3;13(19):9918-9930
Food & function 2022 Oct 3;13(19):9918-9930
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345
Aging 2022 Oct 27;14(20):8321-8345
Myocytic androgen receptor overexpression does not affect sex differences in adaptation to chronic endurance exercise.
Barsky ST, Monks DA
Biology of sex differences 2022 Oct 23;13(1):59
Biology of sex differences 2022 Oct 23;13(1):59
SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways.
Zhuang X, Ma J, Xu G, Sun Z
Molecular medicine (Cambridge, Mass.) 2022 Oct 22;28(1):125
Molecular medicine (Cambridge, Mass.) 2022 Oct 22;28(1):125
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Tai H, Cui XZ, He J, Lan ZM, Li SM, Li LB, Yao SC, Jiang XL, Meng XS, Kuang JS
Aging 2022 Oct 20;14(20):8302-8320
Aging 2022 Oct 20;14(20):8302-8320
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Zeng X, Ren D, Li D, Du H, Yang X
Food & function 2022 Oct 17;13(20):10651-10664
Food & function 2022 Oct 17;13(20):10651-10664
Dihydromyricetin alters myosin heavy chain expression via AMPK signaling pathway in porcine myotubes.
Guo Z, Chen X, Chen D, Yu B, He J, Zheng P, Luo Y, Chen H, Yan H, Huang Z
Food & function 2022 Oct 17;13(20):10525-10534
Food & function 2022 Oct 17;13(20):10525-10534
The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression.
Luo XM, Lam SM, Dong Y, Ma XJ, Yan C, Zhang YJ, Cao Y, Su L, Lu G, Yang JK, Shui G, Feng YM
Communications biology 2022 Oct 12;5(1):1088
Communications biology 2022 Oct 12;5(1):1088
Indole-3-acetic acid improves the hepatic mitochondrial respiration defects by PGC1a up-regulation.
Zhang C, Fu Q, Shao K, Liu L, Ma X, Zhang F, Zhang X, Meng L, Yan C, Zhao X
Cellular signalling 2022 Nov;99:110442
Cellular signalling 2022 Nov;99:110442
Insufficient sleep disrupts glucose metabolism during pregnancy by inhibiting PGC-1α.
Wu H, Lu C, Li X, Xu X, Wu S
Annals of translational medicine 2022 Nov;10(22):1241
Annals of translational medicine 2022 Nov;10(22):1241
Targeting Wnt/β-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITF.
Wang H, Zhang H, Chen Y, Wang H, Tian Y, Yi X, Shi Q, Zhao T, Zhang B, Gao T, Guo S, Li C, Guo W
Cells 2022 Nov 12;11(22)
Cells 2022 Nov 12;11(22)
Anti-fatigue effects of fermented soybean protein peptides in mice.
Fang L, Zhang RX, Wei Y, Ling K, Lu L, Wang J, Pan XC, Cai MY
Journal of the science of food and agriculture 2022 May;102(7):2693-2703
Journal of the science of food and agriculture 2022 May;102(7):2693-2703
Piperine Improves Lipid Dysregulation by Modulating Circadian Genes Bmal1 and Clock in HepG2 Cells.
Zhang W, Ho CT, Lu M
International journal of molecular sciences 2022 May 17;23(10)
International journal of molecular sciences 2022 May 17;23(10)
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
Wei S, Yin D, Yu S, Lin X, Savani MR, Du K, Ku Y, Wu D, Li S, Liu H, Tian M, Chen Y, Bowie M, Hariharan S, Waitkus M, Keir ST, Sugarman ET, Deek RA, Labrie M, Khasraw M, Lu Y, Mills GB, Herlyn M, Wu K, Liu L, Wei Z, Flaherty KT, Abdullah K, Zhang G, Ashley DM
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 May 13;28(10):2180-2195
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 May 13;28(10):2180-2195
Sirtuin 6 affects glucose reabsorption and gluconeogenesis in type 1 diabetes via FoxO1.
Bian C, Zhang R, Wang Y, Li J, Song Y, Guo D, Gao J, Ren H
Molecular and cellular endocrinology 2022 May 1;547:111597
Molecular and cellular endocrinology 2022 May 1;547:111597
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2.
Cai B, Ma M, Zhang J, Wang Z, Kong S, Zhou Z, Lian L, Zhang J, Li J, Wang Y, Li H, Zhang X, Nie Q
Molecular therapy. Nucleic acids 2022 Mar 8;27:319-334
Molecular therapy. Nucleic acids 2022 Mar 8;27:319-334
Dihydromyricetin improves meat quality and promotes skeletal muscle fiber type transformations via AMPK signaling in growing-finishing pigs.
Guo Z, Chen X, Huang Z, Chen D, Li M, Yu B, He J, Luo Y, Yan H, Zheng P
Food & function 2022 Mar 21;13(6):3649-3659
Food & function 2022 Mar 21;13(6):3649-3659
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Guan X, Yan Q, Wang D, Du G, Zhou J
Nutrients 2022 Mar 16;14(6)
Nutrients 2022 Mar 16;14(6)
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Tai H, Tong YJ, Yu R, Yu Y, Yao SC, Li LB, Liu Y, Cui XZ, Kuang JS, Meng XS, Jiang XL
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
Li S, Ma Y, Ye S, Su Y, Hu D, Xiao F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113071
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113071
Involvement of Parkin-mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease-related sarcopenia.
Ito A, Hashimoto M, Tanihata J, Matsubayashi S, Sasaki R, Fujimoto S, Kawamoto H, Hosaka Y, Ichikawa A, Kadota T, Fujita Y, Takekoshi D, Ito S, Minagawa S, Numata T, Hara H, Matsuoka T, Udaka J, Araya J, Saito M, Kuwano K
Journal of cachexia, sarcopenia and muscle 2022 Jun;13(3):1864-1882
Journal of cachexia, sarcopenia and muscle 2022 Jun;13(3):1864-1882
The anti-fatigue activity of corn peptides and their effect on gut bacteria.
Feng Z, Wei Y, Xu Y, Zhang R, Li M, Qin H, Gu R, Cai M
Journal of the science of food and agriculture 2022 Jun;102(8):3456-3466
Journal of the science of food and agriculture 2022 Jun;102(8):3456-3466
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway.
Kou G, Li P, Shi Y, Traore SS, Shi X, Amoah AN, Cui Z, Lyu Q
Journal of agricultural and food chemistry 2022 Jun 29;70(25):7704-7715
Journal of agricultural and food chemistry 2022 Jun 29;70(25):7704-7715
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
Chen Z, Wang H, Hu B, Chen X, Zheng M, Liang L, Lyu J, Zeng Q
European journal of histochemistry : EJH 2022 Jun 21;66(3)
European journal of histochemistry : EJH 2022 Jun 21;66(3)
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Zhou M, Dai Y, Ma Y, Yan Y, Hua M, Gao Q, Geng X, Zhou Q
Molecules (Basel, Switzerland) 2022 Jun 14;27(12)
Molecules (Basel, Switzerland) 2022 Jun 14;27(12)
Exerkine apelin reverses obesity-associated placental dysfunction by accelerating mitochondrial biogenesis in mice.
Chae SA, Son JS, Zhao L, Gao Y, Liu X, Marie de Avila J, Zhu MJ, Du M
American journal of physiology. Endocrinology and metabolism 2022 Jun 1;322(6):E467-E479
American journal of physiology. Endocrinology and metabolism 2022 Jun 1;322(6):E467-E479
Inhibition of polycomb repressive complex 2 by targeting EED protects against cisplatin-induced acute kidney injury.
Yu C, Li T, Li J, Cui B, Liu N, Bayliss G, Zhuang S
Journal of cellular and molecular medicine 2022 Jul;26(14):4061-4075
Journal of cellular and molecular medicine 2022 Jul;26(14):4061-4075
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Xiong Z, Yang F, Xu T, Yang Y, Wang F, Zhou G, Wang Q, Guo X, Xing C, Bai H, Chen J, Wu Y, Yang S, Cao H
Journal of inorganic biochemistry 2022 Jul;232:111818
Journal of inorganic biochemistry 2022 Jul;232:111818
Exposure to Bisphenol A Caused Hepatoxicity and Intestinal Flora Disorder in Rats.
Liu R, Liu B, Tian L, Jiang X, Li X, Cai D, Sun J, Bai W, Jin Y
International journal of molecular sciences 2022 Jul 21;23(14)
International journal of molecular sciences 2022 Jul 21;23(14)
Effect of Qingyangshen glycosides on social defeat mice model.
Liu D, Wang J, Chang L, Zhu Q, Jiang N, Azhar M, Zeng G
Journal of ethnopharmacology 2022 Jul 15;293:115253
Journal of ethnopharmacology 2022 Jul 15;293:115253
Caloric restriction and Roux-en-Y Gastric Bypass promote white adipose tissue browning in mice.
Huang D, Zhang Z, Dong Z, Liu R, Huang J, Xu G
Journal of endocrinological investigation 2022 Jan;45(1):139-148
Journal of endocrinological investigation 2022 Jan;45(1):139-148
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Hao X, Bu W, Lv G, Xu L, Hou D, Wang J, Liu X, Yang T, Zhang X, Liu Q, Gong Y, Shao C
Oncogene 2022 Jan;41(3):427-443
Oncogene 2022 Jan;41(3):427-443
Sodium butyrate ameliorates the cognitive impairment of Alzheimer's disease by regulating the metabolism of astrocytes.
Wang C, Zheng D, Weng F, Jin Y, He L
Psychopharmacology 2022 Jan;239(1):215-227
Psychopharmacology 2022 Jan;239(1):215-227
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.
Liu J, Jiang J, Qiu J, Wang L, Zhuo J, Wang B, Sun D, Yu S, Lou H
Food & function 2022 Jan 4;13(1):375-385
Food & function 2022 Jan 4;13(1):375-385
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
Li R, Xiao J, Cao Y, Huang Q, Ho CT, Lu M
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
d-Allulose Improves Endurance and Recovery from Exhaustion in Male C57BL/6J Mice.
Liu B, Gou Y, Tsuzuki T, Yamada T, Iida T, Wang S, Banno R, Toyoda Y, Koike T
Nutrients 2022 Jan 18;14(3)
Nutrients 2022 Jan 18;14(3)
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Yu J, Zhu J, Deng J, Shen J, Du F, Wu X, Chen Y, Li M, Wen Q, Xiao Z, Zhao Y
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Arsenic causes mitochondrial biogenesis obstacles by inhibiting the AMPK/PGC-1α signaling pathway and also induces apoptosis and dysregulated mitophagy in the duck liver.
Zhong G, Hu T, Tang L, Li T, Wu S, Duan X, Pan J, Zhang H, Tang Z, Feng X, Hu L
Ecotoxicology and environmental safety 2022 Jan 15;230:113117
Ecotoxicology and environmental safety 2022 Jan 15;230:113117
BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice.
Li L, Zhang H, Chen B, Xia B, Zhu R, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Orekhov AN, Prentki M, Wang L, Guo S, Zhang D
Journal of ethnopharmacology 2022 Jan 10;282:114653
Journal of ethnopharmacology 2022 Jan 10;282:114653
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
Wang X, Yang Y, Zhao D, Zhang S, Chen Y, Chen Y, Feng K, Li X, Han J, Iwakiri Y, Duan Y, Yang X
The Journal of biological chemistry 2022 Feb;298(2):101561
The Journal of biological chemistry 2022 Feb;298(2):101561
High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein.
Shen Z, Wu J, Gao Z, Zhang S, Chen J, He J, Guo Y, Deng Q, Xie Y, Liu J, Zhang J
Nucleic acids research 2022 Feb 28;50(4):2157-2171
Nucleic acids research 2022 Feb 28;50(4):2157-2171
circPTPN4 regulates myogenesis via the miR-499-3p/NAMPT axis.
Cai B, Ma M, Zhou Z, Kong S, Zhang J, Zhang X, Nie Q
Journal of animal science and biotechnology 2022 Feb 14;13(1):2
Journal of animal science and biotechnology 2022 Feb 14;13(1):2
Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway.
Wang Y, Liu B, Wu P, Chu Y, Gui S, Zheng Y, Chen X
Antioxidants (Basel, Switzerland) 2022 Feb 10;11(2)
Antioxidants (Basel, Switzerland) 2022 Feb 10;11(2)
Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.
Kong L, Zhang W, Liu S, Zhong Z, Zheng G
Plant foods for human nutrition (Dordrecht, Netherlands) 2022 Dec;77(4):529-537
Plant foods for human nutrition (Dordrecht, Netherlands) 2022 Dec;77(4):529-537
A plant-derived natural photosynthetic system for improving cell anabolism.
Chen P, Liu X, Gu C, Zhong P, Song N, Li M, Dai Z, Fang X, Liu Z, Zhang J, Tang R, Fan S, Lin X
Nature 2022 Dec;612(7940):546-554
Nature 2022 Dec;612(7940):546-554
Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns.
Liu X, Li D, Liu Z, Song Y, Zhang B, Zang Y, Zhang W, Niu Y, Shen C
Burns : journal of the International Society for Burn Injuries 2022 Dec;48(8):1922-1932
Burns : journal of the International Society for Burn Injuries 2022 Dec;48(8):1922-1932
Dietary L-theanine supplementation improves lipid metabolism and antioxidant capacity in weaning piglets.
Chen X, Chen L, Qin Y, Mao Z, Huang Z, Jia G, Zhao H, Liu G
Animal biotechnology 2022 Dec;33(7):1407-1415
Animal biotechnology 2022 Dec;33(7):1407-1415
Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs.
Tan L, Chen Z, Ruan Y, Xu H
Epigenetics 2022 Dec;17(12):1800-1819
Epigenetics 2022 Dec;17(12):1800-1819
Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway.
Sun J, Leng P, Li X, Guo Q, Zhao J, Liang Y, Zhang X, Yang X, Li J
Adipocyte 2022 Dec;11(1):562-571
Adipocyte 2022 Dec;11(1):562-571
miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes.
Tan X, Zhu T, Zhang L, Fu L, Hu Y, Li H, Li C, Zhang J, Liang B, Liu J
Adipocyte 2022 Dec;11(1):120-132
Adipocyte 2022 Dec;11(1):120-132
Cordycepin exhibits anti-fatigue effect via activating TIGAR/SIRT1/PGC-1α signaling pathway.
Chai X, Pan M, Wang J, Feng M, Wang Y, Zhang Q, Sun Y
Biochemical and biophysical research communications 2022 Dec 31;637:127-135
Biochemical and biophysical research communications 2022 Dec 31;637:127-135
Exercise-derived peptide protects against pathological cardiac remodeling.
Yin A, Yuan R, Xiao Q, Zhang W, Xu K, Yang X, Yang W, Xu L, Wang X, Zhuang F, Li Y, Cai Z, Sun Z, Zhou B, He B, Shen L
EBioMedicine 2022 Aug;82:104164
EBioMedicine 2022 Aug;82:104164
HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway.
Yuan Z, Xiao-Wei L, Juan W, Xiu-Juan L, Nian-Yun Z, Lei S
Journal of physiology and biochemistry 2022 Aug;78(3):641-652
Journal of physiology and biochemistry 2022 Aug;78(3):641-652
Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner.
Zhang S, Wu X, Wang J, Shi Y, Hu Q, Cui W, Bai H, Zhou J, Du Y, Han L, Li L, Feng D, Ge S, Qu Y
Redox biology 2022 Aug;54:102390
Redox biology 2022 Aug;54:102390
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Liu D, Sun H, Li K, Zhao Z, Liu Z, Zhang G, Ge Y, Zhang J, Wang D, Leng Y
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Wang L, Duan Z, Liang M, Wang C, Liang T, Sun L, Yan C, Li Q, Liang T
Chemico-biological interactions 2022 Aug 25;363:110003
Chemico-biological interactions 2022 Aug 25;363:110003
PPARGC1A Is a Moderator of Skeletal Muscle Development Regulated by miR-193b-3p.
Ma M, Cai B, Kong S, Zhou Z, Zhang J, Zhang X, Nie Q
International journal of molecular sciences 2022 Aug 24;23(17)
International journal of molecular sciences 2022 Aug 24;23(17)
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Cheng F, Dun Y, Cheng J, Ripley-Gonzalez JW, Jiang W, You B, Liu S
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Circadian Clock Genes REV-ERBs Inhibits Granulosa Cells Apoptosis by Regulating Mitochondrial Biogenesis and Autophagy in Polycystic Ovary Syndrome.
Sun L, Tian H, Xue S, Ye H, Xue X, Wang R, Liu Y, Zhang C, Chen Q, Gao S
Frontiers in cell and developmental biology 2021;9:658112
Frontiers in cell and developmental biology 2021;9:658112
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Li YQ, Chen Y, Jiang SQ, Shi YY, Jiang XL, Wu SS, Zhou P, Wang HY, Li P, Li F
Frontiers in cell and developmental biology 2021;9:652310
Frontiers in cell and developmental biology 2021;9:652310
Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming.
Li W, Wang S, Zhang H, Li B, Xu L, Li Y, Kong C, Jiao H, Wang Y, Pang Y, Qin W, Jia L, Jia J
Journal of Alzheimer's disease : JAD 2021;82(4):1475-1485
Journal of Alzheimer's disease : JAD 2021;82(4):1475-1485
Construction and Validation of a Combined Ferroptosis and Hypoxia Prognostic Signature for Hepatocellular Carcinoma.
Wen K, Yan Y, Shi J, Hu L, Wang W, Liao H, Li H, Zhu Y, Mao K, Xiao Z
Frontiers in molecular biosciences 2021;8:809672
Frontiers in molecular biosciences 2021;8:809672
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Xiong Z, Xing C, Xu T, Yang Y, Liu G, Hu G, Cao H, Zhang C, Guo X, Yang F
Frontiers in veterinary science 2021;8:756534
Frontiers in veterinary science 2021;8:756534
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Wu X, Zhang T, Lyu P, Chen M, Ni G, Cheng H, Xu G, Li X, Wang L, Shang H
Frontiers in cardiovascular medicine 2021;8:698056
Frontiers in cardiovascular medicine 2021;8:698056
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Tai H, Jiang XL, Song N, Xiao HH, Li Y, Cheng MJ, Yin XM, Chen YR, Yang GL, Jiang XY, Kuang JS, Lan ZM, Jia LQ
Frontiers in medicine 2021;8:617393
Frontiers in medicine 2021;8:617393
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218
International journal of endocrinology 2021;2021:8867218
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
He H, Li C, Lu X, Li Y, Li X, Sun X, Tang B, Wu Y, Li C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism.
Cao Z, Pan J, Sui X, Fang C, Li N, Huang X, Qu X, Han D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5590623
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5590623
ZLN005 protects against ischemia-reperfusion-induced kidney injury by mitigating oxidative stress through the restoration of mitochondrial fatty acid oxidation.
Wang Z, Fu Z, Wang C, Xu J, Ma H, Jiang M, Xu T, Feng X, Zhang W
American journal of translational research 2021;13(9):10014-10037
American journal of translational research 2021;13(9):10014-10037
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X, Zheng Q
Frontiers in pharmacology 2021;12:771940
Frontiers in pharmacology 2021;12:771940
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Yin Z, Geng X, Zhang Z, Wang Y, Gao X
Frontiers in pharmacology 2021;12:746711
Frontiers in pharmacology 2021;12:746711
Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK.
Yang Y, Wu Y, Zou J, Wang YH, Xu MX, Huang W, Yu DJ, Zhang L, Zhang YY, Sun XD
Frontiers in pharmacology 2021;12:687095
Frontiers in pharmacology 2021;12:687095
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Liu Y, Fu X, Chen Z, Luo T, Zhu C, Ji Y, Bian Z
Frontiers in pharmacology 2021;12:665894
Frontiers in pharmacology 2021;12:665894
The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR.
Zeng S, Zhao Z, Zheng S, Wu M, Song X, Li Y, Zheng Y, Liu B, Chen L, Gao C, Liu H
Redox biology 2021 Sep;45:102058
Redox biology 2021 Sep;45:102058
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.
Fu F, Liu C, Shi R, Li M, Zhang M, Du Y, Wang Q, Li J, Wang G, Pei J, Ding M
Antioxidants & redox signaling 2021 Sep;35(8):618-641
Antioxidants & redox signaling 2021 Sep;35(8):618-641
A novel supplement with yeast β-glucan, prebiotic, minerals and Silybum marianum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice.
Nehmi VA, Murata GM, Moraes RCM, Lima GCA, De Miranda DA, Radloff K, Costa RGF, Jesus JCR, De Freitas JA, Viana NI, Pimenta R, Leite KRM, Otoch JP, Pessoa AFM
Journal of integrative medicine 2021 Sep;19(5):439-450
Journal of integrative medicine 2021 Sep;19(5):439-450
Effects of dietary ferulic acid supplementation on growth performance and skeletal muscle fiber type conversion in weaned piglets.
Wang Y, Chen X, Huang Z, Chen D, Yu B, Chen H, Yu J, Luo Y, Zheng P, He J
Journal of the science of food and agriculture 2021 Sep;101(12):5116-5123
Journal of the science of food and agriculture 2021 Sep;101(12):5116-5123
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Zhang W, You B, Qi D, Qiu L, Ripley-Gonzalez JW, Zheng F, Fu S, Li C, Dun Y, Liu S
Scientific reports 2021 Sep 27;11(1):19116
Scientific reports 2021 Sep 27;11(1):19116
Multiplexed quantitative evaluation on mitochondrial toxicity of tris (2,3-dibromopropyl) phosphate in hepatocyte.
Ma X, Lu D, Liu Y, Le Y, Chen H, Li X, Wang C
Ecotoxicology and environmental safety 2021 Sep 15;221:112425
Ecotoxicology and environmental safety 2021 Sep 15;221:112425
DRD1 agonist A-68930 improves mitochondrial dysfunction and cognitive deficits in a streptozotocin-induced mouse model.
Cheng ZY, Hu YH, Xia QP, Wang C, He L
Brain research bulletin 2021 Oct;175:136-149
Brain research bulletin 2021 Oct;175:136-149
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Li Y, Sun X, Bai Y, Ji Y, Ren H, Yu X, Yan Y, He X, Dong Y, Zhang L, Luo X, Wang H
Aging 2021 Oct 5;13(19):22985-23003
Aging 2021 Oct 5;13(19):22985-23003
Differentiation of THP-1 monocytes to macrophages increased mitochondrial DNA copy number but did not increase expression of mitochondrial respiratory proteins or mitochondrial transcription factor A.
Okamoto M, Shimogishi M, Nakamura A, Suga Y, Sugawara K, Sato M, Nishi R, Fujisawa A, Yamamoto Y, Kashiba M
Archives of biochemistry and biophysics 2021 Oct 15;710:108988
Archives of biochemistry and biophysics 2021 Oct 15;710:108988
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Li P, Zhang S, Song H, Traore SS, Li J, Raubenheimer D, Cui Z, Kou G
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Li Z, Li Q, Wang L, Li C, Xu M, Duan Y, Ma L, Li T, Chen Q, Wang Y, Wang Y, Feng J, Yin X, Wang X, Han J, Lu C
Redox biology 2021 Nov;47:102156
Redox biology 2021 Nov;47:102156
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance.
Chen YT, Yang QY, Hu Y, Liu XD, de Avila JM, Zhu MJ, Nathanielsz PW, Du M
Nature communications 2021 Nov 25;12(1):6845
Nature communications 2021 Nov 25;12(1):6845
Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation.
Zhang L, Wang YN, Ju JM, Shabanova A, Li Y, Fang RN, Sun JB, Guo YY, Jin TZ, Liu YY, Li TY, Shan HL, Liang HH, Yang BF
Acta pharmacologica Sinica 2021 May;42(5):691-700
Acta pharmacologica Sinica 2021 May;42(5):691-700
Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway.
Wu L, Yan Q, Chen F, Cao C, Wang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111187
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111187
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
Li Y, Kang J, Fu J, Luo H, Liu Y, Li Y, Sun L
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Tai H, Jiang XL, Lan ZM, Li Y, Kong L, Yao SC, Song N, Lv MJ, Wu J, Yang P, Xiao XS, Yang GL, Kuang JS, Jia LQ
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
Embryonic exposure to hyper glucocorticoids suppresses brown fat development and thermogenesis via REDD1.
Chen YT, Hu Y, Yang QY, Liu XD, Son JS, de Avila JM, Zhu MJ, Du M
Science bulletin 2021 Mar 15;66(5):478-489
Science bulletin 2021 Mar 15;66(5):478-489
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Fu X, Jiao J, Qin T, Yu J, Fu Q, Deng X, Ma S, Ma Z
Neurotoxicity research 2021 Jun;39(3):872-885
Neurotoxicity research 2021 Jun;39(3):872-885
Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK.
Wu Y, Yang Y, Li F, Zou J, Wang YH, Xu MX, Wang YL, Li RX, Sun YT, Lu S, Zhang YY, Sun XD
Journal of clinical and translational hepatology 2021 Jun 28;9(3):373-383
Journal of clinical and translational hepatology 2021 Jun 28;9(3):373-383
Bezafibrate prevents aging in in vitro-matured porcine oocytes.
Kim JY, Zhou D, Cui XS
Journal of animal science and technology 2021 Jul;63(4):766-777
Journal of animal science and technology 2021 Jul;63(4):766-777
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Qu Z, Liu A, Liu C, Tang Q, Zhan L, Xiao W, Huang J, Liu Z, Zhang S
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS.
Huang C, Li J, Zhang G, Lin Y, Li C, Zheng X, Song X, Han B, Guo B, Tu Z, Zhang J, Sun Y, Wang Y, Zhang Z, Yan S
Human molecular genetics 2021 Jul 28;30(16):1484-1496
Human molecular genetics 2021 Jul 28;30(16):1484-1496
Immunotherapy against angiotensin II receptor ameliorated insulin resistance in a leptin receptor-dependent manner.
Zheng J, Ding J, Liao M, Qiu Z, Yuan Q, Mai W, Dai Y, Zhang H, Wu H, Wang Y, Liao Y, Chen X, Cheng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21157
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21157
Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice.
Lai H, Nie T, Zhang Y, Chen Y, Tao J, Lin T, Ge T, Li F, Li H
Biological trace element research 2021 Jan;199(1):185-196
Biological trace element research 2021 Jan;199(1):185-196
Zinc-α2-glycoprotein promotes skeletal muscle lipid metabolism in cold-stressed mice.
Fan G, Li Y, Ma F, Zhao R, Yang X
Endocrine journal 2021 Jan 28;68(1):53-62
Endocrine journal 2021 Jan 28;68(1):53-62
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Yang W, Liu J, Hou L, Chen Q, Liu Y
Life sciences 2021 Jan 15;265:118796
Life sciences 2021 Jan 15;265:118796
Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.
Liang J, Zhou X, Wang J, Fei ZY, Qin GC, Zhang DK, Zhou JY, Chen LX
Neuroreport 2021 Jan 13;32(2):144-156
Neuroreport 2021 Jan 13;32(2):144-156
PGC1α regulates mitochondrial oxidative phosphorylation involved in cisplatin resistance in ovarian cancer cells via nucleo-mitochondrial transcriptional feedback.
Shen L, Zhou L, Xia M, Lin N, Ma J, Dong D, Sun L
Experimental cell research 2021 Jan 1;398(1):112369
Experimental cell research 2021 Jan 1;398(1):112369
20-HETE synthesis inhibition attenuates traumatic brain injury-induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC-1α pathway: A translational study.
Cui W, Wu X, Shi Y, Guo W, Luo J, Liu H, Zheng L, Du Y, Wang P, Wang Q, Feng D, Ge S, Qu Y
Cell proliferation 2021 Feb;54(2):e12964
Cell proliferation 2021 Feb;54(2):e12964
Nobiletin activates thermogenesis of brown and white adipose tissue in high-fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Kou G, Li P, Hu Y, Chen H, Nyantakyiwaa Amoah A, Seydou Traore S, Cui Z, Lyu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21267
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21267
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway.
Wang W, Xu RL, He P, Chen R
Journal of inflammation (London, England) 2021 Feb 8;18(1):8
Journal of inflammation (London, England) 2021 Feb 8;18(1):8
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Han X, Guo J, Gao Y, Zhan J, You Y, Huang W
Food & function 2021 Feb 15;12(3):1262-1270
Food & function 2021 Feb 15;12(3):1262-1270
Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease.
Zhang H, Lu J, Liu H, Guan L, Xu S, Wang Z, Qiu Y, Liu H, Peng L, Men X
Pharmacological research 2021 Dec;174:105964
Pharmacological research 2021 Dec;174:105964
β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis.
Chen N, Ge MM, Li DY, Wang XM, Liu DQ, Ye DW, Tian YK, Zhou YQ, Chen JP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112331
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112331
Danqi Tablet () Regulates Energy Metabolism in Ischemic Heart Rat Model through AMPK/SIRT1-PGC-1α Pathway.
Meng H, Wang QY, Li N, He H, Lu WJ, Wang QX, Sun XQ, Jiao SH, Wang Y, Tu PF
Chinese journal of integrative medicine 2021 Aug;27(8):597-603
Chinese journal of integrative medicine 2021 Aug;27(8):597-603
A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer's Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3.
Li Y, Lu J, Cao X, Zhao H, Gao L, Xia P, Pei G
Oxidative medicine and cellular longevity 2020;2020:7698560
Oxidative medicine and cellular longevity 2020;2020:7698560
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, Zhu M, Miao C
Oxidative medicine and cellular longevity 2020;2020:3985089
Oxidative medicine and cellular longevity 2020;2020:3985089
Network Pharmacology Approach to Explore the Potential Mechanisms of Jieduan-Niwan Formula Treating Acute-on-Chronic Liver Failure.
Liang J, Wu M, Bai C, Ma C, Fang P, Hou W, Wei X, Zhang Q, Du Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1041307
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1041307
Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy.
Zhu Z, Li H, Chen W, Cui Y, Huang A, Qi X
Frontiers in pharmacology 2020;11:94
Frontiers in pharmacology 2020;11:94
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Zheng L, Rao Z, Guo Y, Chen P, Xiao W
Frontiers in endocrinology 2020;11:561
Frontiers in endocrinology 2020;11:561
Postnatal growth retardation is associated with intestinal mucosa mitochondrial dysfunction and aberrant energy status in piglets.
Qi M, Wang J, Tan B, Liao S, Long C, Yin Y
Journal of cellular and molecular medicine 2020 Sep;24(17):10100-10111
Journal of cellular and molecular medicine 2020 Sep;24(17):10100-10111
SR18292 exerts potent antitumor effects in multiple myeloma via inhibition of oxidative phosphorylation.
Xiang Y, Fang B, Liu Y, Yan S, Cao D, Mei H, Wang Q, Hu Y, Guo T
Life sciences 2020 Sep 1;256:117971
Life sciences 2020 Sep 1;256:117971
MiR-23a-5p exacerbates intestinal ischemia-reperfusion injury by promoting oxidative stress via targeting PPAR alpha.
Li LX, Yin LH, Gao M, Xu LN, Qi Y, Peng JY
Biochemical pharmacology 2020 Oct;180:114194
Biochemical pharmacology 2020 Oct;180:114194
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Li L, Chu X, Yao Y, Cao J, Li Q, Ma H
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Flavin adenine dinucleotide ameliorates hypertensive vascular remodeling via activating short chain acyl-CoA dehydrogenase.
Zhong X, Ma Z, Su Y, Li Z, Liao Y, Pan X, Zang L, Zhou S
Life sciences 2020 Oct 1;258:118156
Life sciences 2020 Oct 1;258:118156
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Hu Y, Xu W, Zeng H, He Z, Lu X, Zuo D, Qin G, Chen W
British journal of cancer 2020 Nov;123(11):1644-1655
British journal of cancer 2020 Nov;123(11):1644-1655
Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation.
Shen S, Faouzi S, Souquere S, Roy S, Routier E, Libenciuc C, André F, Pierron G, Scoazec JY, Robert C
Cell reports 2020 Nov 24;33(8):108421
Cell reports 2020 Nov 24;33(8):108421
A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility.
Wei M, Huang F, Zhao L, Zhang Y, Yang W, Wang S, Li M, Han X, Ge K, Qu C, Rajani C, Xie G, Zheng X, Zhao A, Bian Z, Jia W
EBioMedicine 2020 May;55:102766
EBioMedicine 2020 May;55:102766
Effect of sitagliptin on expression of skeletal muscle peroxisome proliferator-activated receptor γ coactivator-1α and irisin in a rat model of type 2 diabetes mellitus.
Liu Y, Xu F, Jiang P
The Journal of international medical research 2020 May;48(5):300060519885569
The Journal of international medical research 2020 May;48(5):300060519885569
Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway.
Luo J, Tang C, Chen X, Ren Z, Qu H, Chen R, Tong Z
International journal of environmental research and public health 2020 Mar 19;17(6)
International journal of environmental research and public health 2020 Mar 19;17(6)
Resveratrol prevents benzo(a)pyrene-induced disruption of mitochondrial homeostasis via the AMPK signaling pathway in primary cultured neurons.
Kang RR, Sun Q, Chen KG, Cao QT, Liu C, Liu K, Ma Z, Deng Y, Liu W, Xu B
Environmental pollution (Barking, Essex : 1987) 2020 Jun;261:114207
Environmental pollution (Barking, Essex : 1987) 2020 Jun;261:114207
p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis.
Li J, Li Y, Chen L, Yu B, Xue Y, Guo R, Su J, Liu Y, Sun L
Molecular medicine reports 2020 Jul;22(1):155-164
Molecular medicine reports 2020 Jul;22(1):155-164
Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs.
Niu YJ, Zhou W, Nie ZW, Zhou D, Xu YN, Ock SA, Yan CG, Cui XS
Aging 2020 Jan 20;12(2):1256-1271
Aging 2020 Jan 20;12(2):1256-1271
Myopathy reversion in mice after restauration of mitochondrial complex I.
Pereira CV, Peralta S, Arguello T, Bacman SR, Diaz F, Moraes CT
EMBO molecular medicine 2020 Feb 7;12(2):e10674
EMBO molecular medicine 2020 Feb 7;12(2):e10674
Zinc-α2-glycoprotein promotes browning of white adipose tissue in cold-exposed male mice.
Fan G, Dang X, Li Y, Chen J, Zhao R, Yang X
Molecular and cellular endocrinology 2020 Feb 5;501:110669
Molecular and cellular endocrinology 2020 Feb 5;501:110669
Si-Miao-Yong-An decoction preserves cardiac function and regulates GLC/AMPK/NF-κB and GLC/PPARα/PGC-1α pathways in diabetic mice.
Li L, Chen X, Su C, Wang Q, Li R, Jiao W, Luo H, Tian Y, Tang J, Li X, Liu B, Wang W, Zhang D, Guo S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110817
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110817
Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.
Son JS, Chae SA, Wang H, Chen Y, Bravo Iniguez A, de Avila JM, Jiang Z, Zhu MJ, Du M
Cell reports 2020 Dec 1;33(9):108461
Cell reports 2020 Dec 1;33(9):108461
Excessive Glucocorticoids During Pregnancy Impair Fetal Brown Fat Development and Predispose Offspring to Metabolic Dysfunctions.
Chen YT, Hu Y, Yang QY, Son JS, Liu XD, de Avila JM, Zhu MJ, Du M
Diabetes 2020 Aug;69(8):1662-1674
Diabetes 2020 Aug;69(8):1662-1674
(-)-Hydroxycitric acid regulates energy metabolism by activation of AMPK - PGC1α - NRF1 signal pathway in primary chicken hepatocytes.
Li L, Jiang Z, Yao Y, Yang Z, Ma H
Life sciences 2020 Aug 1;254:117785
Life sciences 2020 Aug 1;254:117785
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762
Life sciences 2020 Aug 1;254:117762
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Zhu R, Wei J, Liu H, Liu C, Wang L, Chen B, Li L, Jia Q, Tian Y, Li R, Zhao D, Mo F, Li Y, Gao S, Wang XD, Zhang D
The Journal of nutritional biochemistry 2020 Apr;78:108335
The Journal of nutritional biochemistry 2020 Apr;78:108335
Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice.
Son JS, Zhao L, Chen Y, Chen K, Chae SA, de Avila JM, Wang H, Zhu MJ, Jiang Z, Du M
Science advances 2020 Apr;6(16):eaaz0359
Science advances 2020 Apr;6(16):eaaz0359
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Wang Y, Gao M, Zhu F, Li X, Yang Y, Yan Q, Jia L, Xie L, Chen Z
Nature communications 2020 Apr 3;11(1):1648
Nature communications 2020 Apr 3;11(1):1648
MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line.
Zhang Q, Ma XF, Dong MZ, Tan J, Zhang J, Zhuang LK, Liu SS, Xin YN
Lipids in health and disease 2020 Apr 16;19(1):76
Lipids in health and disease 2020 Apr 16;19(1):76
Methane-Rich Saline: A Potential Resuscitation Fluid for Hemorrhagic Shock.
Tong Y, Dong Y, Feng Y, Li Z, Jia Y, Zhang X, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2019;2019:4929107
Oxidative medicine and cellular longevity 2019;2019:4929107
MOTS-c inhibits Osteolysis in the Mouse Calvaria by affecting osteocyte-osteoclast crosstalk and inhibiting inflammation.
Yan Z, Zhu S, Wang H, Wang L, Du T, Ye Z, Zhai D, Zhu Z, Tian X, Lu Z, Cao X
Pharmacological research 2019 Sep;147:104381
Pharmacological research 2019 Sep;147:104381
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
Role of the aryl hydrocarbon receptor signaling pathway in promoting mitochondrial biogenesis against oxidative damage in human melanocytes.
Wang X, Li S, Liu L, Jian Z, Cui T, Yang Y, Guo S, Yi X, Wang G, Li C, Gao T, Li K
Journal of dermatological science 2019 Oct;96(1):33-41
Journal of dermatological science 2019 Oct;96(1):33-41
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, Liu K, Sun H
Pharmacological research 2019 Oct;148:104414
Pharmacological research 2019 Oct;148:104414
High-intensity interval training changes the expression of muscle RING-finger protein-1 and muscle atrophy F-box proteins and proteins involved in the mechanistic target of rapamycin pathway and autophagy in rat skeletal muscle.
Cui X, Zhang Y, Wang Z, Yu J, Kong Z, Ružić L
Experimental physiology 2019 Oct;104(10):1505-1517
Experimental physiology 2019 Oct;104(10):1505-1517
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Chen TT, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, Yin J, Liu C, Cao J
Biomolecules 2019 Oct 25;9(11)
Biomolecules 2019 Oct 25;9(11)
Maternal Eicosapentaenoic Acid Feeding Decreases Placental Lipid Deposition and Improves the Homeostasis of Oxidative Stress Through a Sirtuin-1 (SIRT1) Independent Manner.
Peng J, Xiong J, Cui C, Huang N, Zhang H, Wu X, Yang Y, Zhou Y, Wei H, Peng J
Molecular nutrition & food research 2019 Nov;63(21):e1900343
Molecular nutrition & food research 2019 Nov;63(21):e1900343
Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy.
Essandoh K, Wang X, Huang W, Deng S, Gardner G, Mu X, Li Y, Kranias EG, Wang Y, Fan GC
The Journal of biological chemistry 2019 Nov 29;294(48):18057-18068
The Journal of biological chemistry 2019 Nov 29;294(48):18057-18068
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
Lv X, Wang X, Wang Y, Zhou D, Li W, Wilson JX, Chang H, Huang G
Aging 2019 Nov 22;11(22):10356-10373
Aging 2019 Nov 22;11(22):10356-10373
(-)-Hydroxycitric Acid Suppresses Lipid Droplet Accumulation and Accelerates Energy Metabolism via Activation of the Adiponectin-AMPK Signaling Pathway in Broiler Chickens.
Li L, Zhang H, Yao Y, Yang Z, Ma H
Journal of agricultural and food chemistry 2019 Mar 20;67(11):3188-3197
Journal of agricultural and food chemistry 2019 Mar 20;67(11):3188-3197
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, Shan Q, Liu S
Environment international 2019 Jul;128:146-157
Environment international 2019 Jul;128:146-157
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, Zhang Y, Li B, Shan Y
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Molecular nutrition & food research 2019 Feb;63(4):e1800795
FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake.
Li L, Zhao H, Chen B, Fan Z, Li N, Yue J, Ye Q
Journal of translational medicine 2019 Dec 13;17(1):418
Journal of translational medicine 2019 Dec 13;17(1):418
Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway.
Liu B, Jin J, Zhang Z, Zuo L, Jiang M, Xie C
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):397-405
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):397-405
The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα.
Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, Montagner A, Chretien D, Rugarli EI, Guillou H, Pende M, Panasyuk G
Nature communications 2019 Apr 5;10(1):1566
Nature communications 2019 Apr 5;10(1):1566
Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice.
Liu M, Zhu H, Dai Y, Pan H, Li N, Wang L, Yang H, Yan K, Gong F
Frontiers in physiology 2018;9:62
Frontiers in physiology 2018;9:62
Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases in Vitro and in Vivo: Regulation of Redox Biology and Mitochondrial Function.
Li X, Cui XX, Chen YJ, Wu TT, Xu H, Yin H, Wu YC
Frontiers in aging neuroscience 2018;10:121
Frontiers in aging neuroscience 2018;10:121
Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS.
Dervishi I, Gozutok O, Murnan K, Gautam M, Heller D, Bigio E, Ozdinler PH
Scientific reports 2018 Oct 3;8(1):14732
Scientific reports 2018 Oct 3;8(1):14732
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression.
Wu G, Wen M, Sun L, Li H, Liu Y, Li R, Wu F, Yang R, Lin Y
RSC advances 2018 Nov 1;8(65):37117-37128
RSC advances 2018 Nov 1;8(65):37117-37128
The Role of Mitochondria in Methamphetamine-induced inhibitory effects on osteogenesis of Mesenchymal Stem Cells.
Shen Y, Wu L, Wang J, Wu X, Zhang X
European journal of pharmacology 2018 May 5;826:56-65
European journal of pharmacology 2018 May 5;826:56-65
AMPK/α-Ketoglutarate Axis Regulates Intestinal Water and Ion Homeostasis in Young Pigs.
He L, Huang N, Li H, Tian J, Zhou X, Li T, Yao K, Wu G, Yin Y
Journal of agricultural and food chemistry 2017 Mar 22;65(11):2287-2298
Journal of agricultural and food chemistry 2017 Mar 22;65(11):2287-2298
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Zhu E, Yang Y, Zhang J, Li Y, Li C, Chen L, Sun B
Oncotarget 2016 Dec 6;7(49):81077-81089
Oncotarget 2016 Dec 6;7(49):81077-81089
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