abx011860

antibody from Abbexa

Targeting: PPARGC1A PGC-1alpha, PGC1, PGC1A, PPARGC1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx011860

Provider

Abbexa

Product name

Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) Antibody

Antibody type

Monoclonal

Description

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.