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- References [15]
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- Product number
- 18333-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18333-1-AP, RRID:AB_2176586
- Product name
- RAD18 antibody
- Antibody type
- Polyclonal
- Description
- RAD18 antibody (Cat. #18333-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Advancing inducible gene-inactivation systems to explore synthetic lethality.
Chromatin assembly factor 1 subunit A promotes TLS pathway by recruiting E3 ubiquitin ligase RAD18 in cancer cells.
Risk of cervical squamous cell carcinoma associated with a single nucleotide polymorphism in the RAD18 gene in the Chinese population and its significance as a predictive biomarker.
ADAR1 enhances tumor proliferation and radioresistance in non-small cell lung cancer by interacting with Rad18.
Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair.
Hepatocellular Carcinoma LINC01116 Outcompetes T Cells for Linoleic Acid and Accelerates Tumor Progression.
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis.
UBE2B promotes ovarian cancer growth via promoting RAD18 mediated ZMYM2 monoubiquitination and stabilization.
A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis.
Regulation of the DNA damage response on male meiotic sex chromosomes.
RNF168 forms a functional complex with RAD6 during the DNA damage response.
A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci.
DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents.
REV1 and polymerase ζ facilitate homologous recombination repair.
Sánta ÁT, Gráf A, Vincze-Kontár K, Kovács K, Bóna B, Mórocz M, Kiss E, Haracska L
NAR cancer 2026 Mar;8(1):zcag004
NAR cancer 2026 Mar;8(1):zcag004
Chromatin assembly factor 1 subunit A promotes TLS pathway by recruiting E3 ubiquitin ligase RAD18 in cancer cells.
Wen B, Zheng HX, Heng JH, Tang Q, Deng DX, Zhang ZD, Liao LD, Xu LY, Li EM
Cell death & disease 2025 Mar 1;16(1):147
Cell death & disease 2025 Mar 1;16(1):147
Risk of cervical squamous cell carcinoma associated with a single nucleotide polymorphism in the RAD18 gene in the Chinese population and its significance as a predictive biomarker.
Zhang R, Kong J, Li Y, Wang H, Cheng Q, Zhou C, Yu M, Wang Y, Ye F
Medicine 2025 Aug 22;104(34):e44017
Medicine 2025 Aug 22;104(34):e44017
ADAR1 enhances tumor proliferation and radioresistance in non-small cell lung cancer by interacting with Rad18.
Tian C, Li C, Wang J, Liu Y, Gao J, Hong X, Gu F, Zhang K, Hu Y, Fan H, Liu L, Zeng Y
Cellular oncology (Dordrecht, Netherlands) 2025 Apr;48(2):471-485
Cellular oncology (Dordrecht, Netherlands) 2025 Apr;48(2):471-485
Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair.
Aubé F, Fontrodona N, Guiguettaz L, Vallin E, Fabbri L, Lapendry A, Vagner S, Ricci EP, Auboeuf D
NAR cancer 2024 Jun;6(2):zcae019
NAR cancer 2024 Jun;6(2):zcae019
Hepatocellular Carcinoma LINC01116 Outcompetes T Cells for Linoleic Acid and Accelerates Tumor Progression.
Ma K, Chu J, Liu Y, Sun L, Zhou S, Li X, Ji C, Zhang N, Guo X, Liang S, Cui T, Hu Q, Wang J, Liu Y, Liu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(21):e2400676
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(21):e2400676
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
Zhou H, Feng W, Yu J, Shafiq TA, Paulo JA, Zhang J, Luo Z, Gygi SP, Moazed D
Cell reports 2023 Apr 25;42(4):112339
Cell reports 2023 Apr 25;42(4):112339
REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis.
Chen Y, Jie X, Xing B, Wu Z, Yang X, Rao X, Xu Y, Zhou D, Dong X, Zhang T, Yang K, Li Z, Wu G
Cell death & disease 2022 Feb 3;13(2):110
Cell death & disease 2022 Feb 3;13(2):110
UBE2B promotes ovarian cancer growth via promoting RAD18 mediated ZMYM2 monoubiquitination and stabilization.
Zeng X, Zheng W, Sheng Y, Ma H
Bioengineered 2022 Apr;13(4):8000-8012
Bioengineered 2022 Apr;13(4):8000-8012
A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis.
Zhang Q, Cao C, Gong W, Bao K, Wang Q, Wang Y, Bi L, Ma S, Zhao J, Liu L, Tian S, Zhang K, Yang J, Yao Z, Song N, Shi L
Theranostics 2020;10(23):10769-10790
Theranostics 2020;10(23):10769-10790
Regulation of the DNA damage response on male meiotic sex chromosomes.
Lu LY, Xiong Y, Kuang H, Korakavi G, Yu X
Nature communications 2013;4:2105
Nature communications 2013;4:2105
RNF168 forms a functional complex with RAD6 during the DNA damage response.
Liu C, Wang D, Wu J, Keller J, Ma T, Yu X
Journal of cell science 2013 May 1;126(Pt 9):2042-51
Journal of cell science 2013 May 1;126(Pt 9):2042-51
A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci.
Helchowski CM, Skow LF, Roberts KH, Chute CL, Canman CE
Cell cycle (Georgetown, Tex.) 2013 Dec 15;12(24):3749-58
Cell cycle (Georgetown, Tex.) 2013 Dec 15;12(24):3749-58
DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents.
Sharma S, Shah NA, Joiner AM, Roberts KH, Canman CE
Molecular pharmacology 2012 Jun;81(6):778-87
Molecular pharmacology 2012 Jun;81(6):778-87
REV1 and polymerase ζ facilitate homologous recombination repair.
Sharma S, Hicks JK, Chute CL, Brennan JR, Ahn JY, Glover TW, Canman CE
Nucleic acids research 2012 Jan;40(2):682-91
Nucleic acids research 2012 Jan;40(2):682-91
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAD18 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAD18. This antibody recognizes human,mouse,rat antigen. The RAD18 antibody has been validated for the following applications: ELISA, WB, IP analysis.
