Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS2939 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Synphilin 1 (R846) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 815-867 of Human Synphilin-1.
- Description
- Synphilin-1 (Ï«-synuclein interacting protein, SNCAIP) is a 919 amino acid protein that associates with Ï« synuclein and promotes the formation of cytosolic inclusions in neuronal cells. The synuclein family members, including Ï«-synuclein and ÉÇ-synuclein, are predominantly expressed in the brain, where they influence synaptic regulation and neuronal plasticity. Synphilin-1 contains modular protein domains, such as ankyrin-like repeats and a coiled-coil domain.While both Ï«-synuclein and synphilin-1 are coexpressed in Lewy bodies of patients with Parkinson£ªs disease, only mutations in the gene for Ï«-synuclein have been determined to confer pathogenicity.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of Synphilin-1 (R846) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate