Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN359008 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Synuclein, alpha Interacting Protein (SNCAIP) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The role of synphilin-1 in synaptic function and protein degradation.
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective.
Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin-1 interaction and inclusion body formation.
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
Siah-1 facilitates ubiquitination and degradation of synphilin-1.
Parkin accumulation in aggresomes due to proteasome impairment.
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.
Interaction of alpha-synuclein and synphilin-1: effect of Parkinson's disease-associated mutations.
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.
Krüger R
Cell and tissue research 2004 Oct;318(1):195-9
Cell and tissue research 2004 Oct;318(1):195-9
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective.
Tanaka M, Kim YM, Lee G, Junn E, Iwatsubo T, Mouradian MM
The Journal of biological chemistry 2004 Feb 6;279(6):4625-31
The Journal of biological chemistry 2004 Feb 6;279(6):4625-31
Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin-1 interaction and inclusion body formation.
Lee G, Tanaka M, Park K, Lee SS, Kim YM, Junn E, Lee SH, Mouradian MM
The Journal of biological chemistry 2004 Feb 20;279(8):6834-9
The Journal of biological chemistry 2004 Feb 20;279(8):6834-9
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
Marx FP, Holzmann C, Strauss KM, Li L, Eberhardt O, Gerhardt E, Cookson MR, Hernandez D, Farrer MJ, Kachergus J, Engelender S, Ross CA, Berger K, Schöls L, Schulz JB, Riess O, Krüger R
Human molecular genetics 2003 Jun 1;12(11):1223-31
Human molecular genetics 2003 Jun 1;12(11):1223-31
Siah-1 facilitates ubiquitination and degradation of synphilin-1.
Nagano Y, Yamashita H, Takahashi T, Kishida S, Nakamura T, Iseki E, Hattori N, Mizuno Y, Kikuchi A, Matsumoto M
The Journal of biological chemistry 2003 Dec 19;278(51):51504-14
The Journal of biological chemistry 2003 Dec 19;278(51):51504-14
Parkin accumulation in aggresomes due to proteasome impairment.
Junn E, Lee SS, Suhr UT, Mouradian MM
The Journal of biological chemistry 2002 Dec 6;277(49):47870-7
The Journal of biological chemistry 2002 Dec 6;277(49):47870-7
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.
Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM
Nature medicine 2001 Oct;7(10):1144-50
Nature medicine 2001 Oct;7(10):1144-50
Interaction of alpha-synuclein and synphilin-1: effect of Parkinson's disease-associated mutations.
Kawamata H, McLean PJ, Sharma N, Hyman BT
Journal of neurochemistry 2001 May;77(3):929-34
Journal of neurochemistry 2001 May;77(3):929-34
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.
Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA
Nature genetics 1999 May;22(1):110-4
Nature genetics 1999 May;22(1):110-4
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