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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- sc-25272 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-25272, RRID:AB_627009
- Product name
- Anti-CD2AP
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human
- Host
- Mouse
Submitted references Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts.
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
van Duijn TJ, Anthony EC, Hensbergen PJ, Deelder AM, Hordijk PL
The Journal of biological chemistry 2010 Jun 25;285(26):20137-46
The Journal of biological chemistry 2010 Jun 25;285(26):20137-46
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
Fernandez DR, Telarico T, Bonilla E, Li Q, Banerjee S, Middleton FA, Phillips PE, Crow MK, Oess S, Muller-Esterl W, Perl A
Journal of immunology (Baltimore, Md. : 1950) 2009 Feb 15;182(4):2063-73
Journal of immunology (Baltimore, Md. : 1950) 2009 Feb 15;182(4):2063-73
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Supportive validation
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- Main image
- Experimental details
- Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.
- Validation comment
- Two independent antibodies targeting one protein yielding similar staining patterns. Staining pattern consistent with experimental and/or bioinformatic data.
